CHIMERA

Binding-activated fluorescent DNA/peptide chimeric probes for cancer imaging

Coordinatore	UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA    more  Organization address address: VIA ORAZIO RAIMONDO 18 city: ROMA postcode: 173 contact info Titolo: Dr. Nome: Francesco Cognome: Ricci Email: send email Telefono: +39 6 72594422
Nazionalità Coordinatore	Italy [IT]
Totale costo	119˙700 €
EC contributo	119˙700 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2013-IRSES
Funding Scheme	MC-IRSES
Anno di inizio	2013
Periodo (anno-mese-giorno)	2013-11-01   -   2016-10-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA  Organization address address: VIA ORAZIO RAIMONDO 18 city: ROMA postcode: 173 contact info Titolo: Dr. Nome: Francesco Cognome: Ricci Email: send email Telefono: +39 6 72594422	IT (ROMA)	coordinator	65˙100.00
2	TARTU ULIKOOL  Organization address address: ULIKOOLI 18 city: TARTU postcode: 50090 contact info Titolo: Prof. Nome: Tambet Cognome: Teesalu Email: send email Telefono: +37 2 53974441	EE (TARTU)	participant	54˙600.00

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 Obiettivo del progetto (Objective)

'The overriding goal of this project is to mimic Nature in the design of novel nucleic acid/peptide chimera based nanodevices that can enable cancer imaging. We will design, engineer and optimize highly specific biomolecular nanodevices that undergo binding-induced conformational changes upon target binding and, in doing so, signal the presence of the cancer marker. This scientific goal of great relevance for the clinical implications will be achieved bringing together an international and interdisciplinary group of research teams and building a collaborative environment for research, innovation and technology transfer. This program will allow the exchange of knowledge and expertise through visiting training periods for participating early-stage and experienced researchers. The training will involve each single aspect of probe development and cancer imaging. The research teams involved in this project encompass the requisite expertise and each of them has a particular focus on a single step of optical probe development and testing on cancer cells. This program will help the integration and collaboration among the research teams and the establishment of a long-term collaboration between Europe and key Third Countries.'