CREACTIVE

Collaborative REsearch on ACute Traumatic brain Injury in intensiVe care medicine in Europe

Coordinatore	ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI    more  Organization address address: Via Giuseppe La Masa 19 city: MILANO postcode: 20156 contact info Titolo: Dr. Nome: Guido Cognome: Bertolini Email: send email Telefono: +39 0354535313 Fax: +39 0354535354
Nazionalità Coordinatore	Italy [IT]
Totale costo	7˙032˙384 €
EC contributo	5˙443˙350 €
Programma	FP7-HEALTH Specific Programme "Cooperation": Health
Code Call	FP7-HEALTH-2013-INNOVATION-1
Funding Scheme	CP-IP
Anno di inizio	2013
Periodo (anno-mese-giorno)	2013-10-01   -   2018-09-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI  Organization address address: Via Giuseppe La Masa 19 city: MILANO postcode: 20156 contact info Titolo: Dr. Nome: Guido Cognome: Bertolini Email: send email Telefono: +39 0354535313 Fax: +39 0354535354	IT (MILANO)	coordinator	2˙386˙582.00
2	BEN-GURION UNIVERSITY OF THE NEGEV  Organization address address: Office of the President - Main Campus city: BEER SHEVA postcode: 84105 contact info Titolo: Ms. Nome: Daphna Cognome: Tripto Email: send email Telefono: +972 8 6472443 Fax: +972 8 6472930	IL (BEER SHEVA)	participant	703˙680.00
3	SEMMELWEIS EGYETEM  Organization address address: Ulloi ut 26 city: BUDAPEST postcode: 1085 contact info Titolo: Dr. Nome: Akos Cognome: Csomos Email: send email Telefono: +3620 8259016 Fax: +361 3251148	HU (BUDAPEST)	participant	519˙726.00
4	WARSZAWSKI UNIWERSYTET MEDYCZNY  Organization address address: UL. ZWIRKI I WIGURY 61 city: WARSZAWA postcode: 2091 contact info Titolo: Dr. Nome: Malgorzata Cognome: Mikaszewska- Sokolewicz Email: send email Telefono: +48 225021800 Fax: +4822 5022103	PL (WARSZAWA)	participant	478˙470.00
5	PANEPISTIMIAKO GENIKO NOSOKOMEIO IRAKLEIOU  Organization address address: VOUTES city: IRAKLEIO postcode: 71110 contact info Titolo: Prof. Nome: Dimitris Cognome: Georgopoulos Email: send email Telefono: +30 2810392636	EL (IRAKLEIO)	participant	374˙625.00
6	UNIVERZITETNI KLINICNI CENTER LJUBLJANA  Organization address address: ZALOSKA CESTA 002 city: LJUBLJANA postcode: 1000 contact info Titolo: Mr. Nome: Miha Cognome: žemlja Email: send email Telefono: +386 1 522 21 91 Fax: +386 1 522 12 34	SI (LJUBLJANA)	participant	337˙671.00
7	EDEX-EDUCATIONAL EXCELLENCE CORPORATION LIMITED  Organization address address: MAKEDONITISAS AVENUE 46 city: NICOSIA postcode: 1700 contact info Titolo: Prof. Nome: Theodoros Cognome: Kyprianou Email: send email Telefono: +357 22603809 Fax: +357 22604328	CY (NICOSIA)	participant	314˙645.00
8	SPLOSNA BOLNISNICA NOVO MESTO  Organization address address: SMIHELSKA ULICA 1 city: NOVO MESTO postcode: 8000 contact info Titolo: Dr. Nome: Rafael Cognome: Kaps Email: send email Telefono: +386 73916530 Fax: +386 73321091	SI (NOVO MESTO)	participant	256˙671.00
9	OROBIX Srl  Organization address address: VIA LUDOVICO ANTONIO MURATORI 3 city: Bergamo postcode: 24123 contact info Titolo: Dr. Nome: Luca Cognome: Antiga Email: send email Telefono: 393474000000	IT (Bergamo)	participant	71˙280.00

Mappa

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 Obiettivo del progetto (Objective)

'Traumatic brain injury (TBI) is among the leading causes of death and disability and the main cause of death among the under-45s. Most patients with moderate to severe TBI are admitted to intensive care units (ICUs) The “PROSAFE” ICU network was recently established in 6 European countries through EU funding (PHEA 2007331), and has continued to collect high-quality data beyond the grant duration. In 2011, 225 ICUs had joined PROSAFE, recruiting a total of 73,163 patients, 2,694 of whom were admitted for TBI. Hence the network can expect to enrol 7-9,000 moderate to severe TBI patients in 4 years. The PROSAFE consortium has already focused attention on TBI and has just started collecting additional information on this condition in order to develop a prognostic model to identify centres of excellence in TBI management Aims of proposal are to consolidate the existing network in order to better describe the epidemiology of moderate-severe TBI in 7 countries (Greece has now joined the consortium); build a prognostic model based on short- and long-term outcome measures; identify most effective clinical interventions for optimally treating TBI patients, and recognize the determinants of optimal vs suboptimal performance All TBI-CDEs endorsed by InTBIR will be collected, along with other items needed to develop a sensible prognostic model, permitting the consortium to join forces with international collaborative initiatives in the field Availing of the coordinating institute’s biobank and consolidated expertise in biochemical and genetic biomarkers, the aim is to identify prognostic markers and underlying genetic factors influencing response to treatment and final outcome The PROSAFE consortium is thus in a position to guarantee superior quality data collection in 7 countries and ensure it continues beyond the life of the project. These conditions are essential if the consortium is to contribute to Europe playing a key role in the success of the InTBIR initiative'