DISCO
From DISCOvery to products: A next generation pipeline for the sustainable generation of high-value plant products
| Coordinatore | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE
Organization address
address: EGHAM HILL UNIVERSITY OF LONDON contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Totale costo | 8˙644˙534 € |
| EC contributo | 6˙485˙847 € |
| Programma | FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology |
| Code Call | FP7-KBBE-2013-7-single-stage |
| Funding Scheme | CP-TP |
| Anno di inizio | 2013 |
| Periodo (anno-mese-giorno) | 2013-11-01 - 2017-10-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE
Organization address
address: EGHAM HILL UNIVERSITY OF LONDON contact info |
UK (EGHAM) | coordinator | 977˙036.00 |
| 2 |
MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.
Organization address
address: Hofgartenstrasse 8 contact info |
DE (MUENCHEN) | participant | 659˙600.00 |
| 3 |
TECHNISCHE UNIVERSITAT DORTMUND
Organization address
address: AUGUST SCHMIDT STRASSE 4 contact info |
DE (DORTMUND) | participant | 569˙400.00 |
| 4 |
THE JAMES HUTTON INSTITUTE
Organization address
address: ERROL ROAD INVERGOWRIE contact info |
UK (DUNDEE) | participant | 532˙153.00 |
| 5 |
EUROPEAN RESEARCH AND PROJECT OFFICE GMBH
Organization address
address: Science Park 1, Stuhlsatzenhausweg 69 contact info |
DE (SAARBRUECKEN) | participant | 503˙950.00 |
| 6 |
FUNDACION FRAUNHOFER CHILE RESEARCH
Organization address
address: Avenida Mariano Sanchez Fontecilla 310 contact info |
CL (Santiago de Chile) | participant | 453˙213.00 |
| 7 |
AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE,L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE
Organization address
address: Lungotevere Grande Ammiraglio Thaon di Revel 76 contact info |
IT (ROMA) | participant | 437˙845.00 |
| 8 |
ISRAELI BIOTECHNOLOGY RESEARCH LTD
Organization address
address: PEKERIS 4 LEV HATAMAR BUILDING contact info |
IL (REHOVOT) | participant | 381˙600.00 |
| 9 |
FERMENTED PRODUCT PARTNER
Organization address
address: RUE HERMAN MEGANCK 21 contact info |
BE (GEMBLOUX-LES ISNES) | participant | 366˙080.00 |
| 10 |
THE HEBREW UNIVERSITY OF JERUSALEM.
Organization address
address: GIVAT RAM CAMPUS contact info |
IL (JERUSALEM) | participant | 349˙136.00 |
| 11 |
SB DRUG DISCOVERY LIMITED
Organization address
address: TELFORD PAVILION BLOCK H TODD CAMPUS contact info |
UK (GLASGOW) | participant | 316˙050.00 |
| 12 |
THE AGRICULTURAL RESEARCH ORGANISATION OF ISRAEL - THE VOLCANI CENTRE
Organization address
address: Derech Hamcabim 68 contact info |
IL (BET DAGAN) | participant | 310˙824.00 |
| 13 |
PROPLANTA SRL
Organization address
address: STR IOAN BUDAI DELEANU 28 contact info |
RO (Cluj Napoca) | participant | 300˙320.00 |
| 14 |
IGA TECHNOLOGY SERVICES SRL
Organization address
address: VIA LINUSSIO 51 contact info |
IT (UDINE) | participant | 280˙640.00 |
| 15 |
Boehringer Ingelheim Pharma GmbH & Co. KG
Organization address
address: Birkendorfer Strasse 65 contact info |
DE (Biberach an der Riss) | participant | 48˙000.00 |
Mappa
Word cloud
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Obiettivo del progetto (Objective)
'Plant natural products have been utilised by human civilisation for millennia, providing vital medicines and essential dietary components. More recently bioactive compounds from plant sources have been used in cosmetics, as health supplements and are important components of feedstuffs. Despite significant investments new activities and new sustainable biosources are required to alleviate our reliance on chemical synthesis. In the DISCO project we aim to address these issues and create a framework that can act as a generic pipeline capable of taking discovery through application and validation, to translation and industrial valorisation. Key aspects of the project will be concerned with (i) translating discovery into industrial feasibility and/or commercialisation, (ii) transfer our knowledge gained optimising isoprenoid/terpenoid production to other important terpenoids and different classes of natural products, (iii) maintaining and incorporating the very latest technologies into both the discovery and translational pipelines and (iv) develop “green factories” with integrated biorefining pipelines to reduce or eliminate chemical refining and thus environmental impact. The bioactive molecules and their biochemical pathways targeted include, carotenoids (including apo-carotenoids), terpenoids and tropane alkaloid. For example; ketocarotenoids which are used as colorants in feedstuffs especially aquaculture; colourless carotenes such as phytoene and phytofluene, which are important bioactive ingredients of cosmetics; apo-carotenoids from saffron which are colorants and potent bioactives; the terpenoid solanesol which is used in the production of Coenzyme Q10 and the alkaloid scopolamine which is used as analgesic. The project will have real-life impacts reducing environmental impact, provide new material to benefit human activities and stimulate economic development.'