TRIBE

Transgressive Inheritance in plant Breeding and Evolution

Coordinatore	THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE    more Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	2˙487˙857 €
EC contributo	2˙487˙857 €
Programma	FP7-IDEAS-ERC Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	ERC-2013-ADG
Funding Scheme	ERC-AG
Anno di inizio	2014
Periodo (anno-mese-giorno)	2014-02-01   -   2019-01-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE  Organization address address: The Old Schools, Trinity Lane city: CAMBRIDGE postcode: CB2 1TN contact info Titolo: Ms. Nome: Liesbeth Cognome: Krul Email: send email Telefono: +44 1223 333543 Fax: +44 1223 332988	UK (CAMBRIDGE)	hostInstitution	2˙487˙857.00
2	THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE  Organization address address: The Old Schools, Trinity Lane city: CAMBRIDGE postcode: CB2 1TN contact info Titolo: Prof. Nome: David Cognome: Baulcombe Email: send email Telefono: +441223 3339386 Fax: +441223 332988	UK (CAMBRIDGE)	hostInstitution	2˙487˙857.00

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 Obiettivo del progetto (Objective)

'New varieties of plant and animal are produced by hybridisation of closely related varieties or species. This process generates 'transgressive' traits that are outside the parental range. Transgressive phenotypes in hybrids may involve complementation of genetic differences between the two parents, heterozygous advantage, genetic rearrangements and, from our recent work, epigenetic effects associated with RNA silencing. TRIBE will investigate these effects using tomato for which there is a recently published full genome sequences and for which there are well characterised genetic resources based on hybrids between cultivated tomato and its wild relatives. We propose to map the genome and epigenome of F2-F4 generation hybrids between S. lycopersicum and its wild relative S. pennelli and, in parallel, to find out the level of expression of all genes including those producing small silencing RNAs. These data will provide the first systematic analysis of genomes, their expression and epigenetic modifications in the four post hybridisation generations. TRIBE will also explore details of epigenetic mechanisms associated with transgressive traits with a view to their enhancement or suppression to facilitate conventional plant breeding involving wide crosses between crops and their wild relatives. It will also explore the possibility that there is a legacy of epigenetic marks in tomato that have been induced by ancestral hybridisation events. The final outcome of TRIBE will be a test of the hypothesis that hybridisation is important in evolution because it allows not only the formation of new combinations of genes: it is also a process that induces new heritable variation via epigenetic and RNA silencing based mechanisms. It will generate information that will be central to the the exploitation of hybrids in breeding of crops.It will also generate new information about evolutionary mechanisms that can be integrated into our understanding of the tree of life.'