LIPIDOMICNET
Lipid droplets as dynamic organelles of fat deposition and release: Translational research towards human disease
| Coordinatore | KLINIKUM DER UNIVERSITAET REGENSBURG
Organization address
address: FRANZ JOSEF STRAUSS ALLEE 11 contact info |
| Nazionalità Coordinatore | Germany [DE] |
| Totale costo | 16˙022˙988 € |
| EC contributo | 11˙603˙930 € |
| Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
| Code Call | FP7-HEALTH-2007-A |
| Funding Scheme | CP-IP |
| Anno di inizio | 2008 |
| Periodo (anno-mese-giorno) | 2008-05-01 - 2012-10-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
KLINIKUM DER UNIVERSITAET REGENSBURG
Organization address
address: FRANZ JOSEF STRAUSS ALLEE 11 contact info |
DE (REGENSBURG) | coordinator | 0.00 |
| 2 |
ACADEMISCH ZIEKENHUIS LEIDEN
Organization address
address: Albinusdreef 2 contact info |
NL (LEIDEN) | participant | 0.00 |
| 3 |
BIOBASE GMBH
Organization address
address: Halchtersche Strasse 33 contact info |
DE (WOLFENBUETTEL) | participant | 0.00 |
| 4 |
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZURICH
Organization address
address: Raemistrasse 101 contact info |
CH (ZUERICH) | participant | 0.00 |
| 5 |
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Organization address
address: Meyerhofstrasse 1 contact info |
DE (HEIDELBERG) | participant | 0.00 |
| 6 |
FONDAZIONE MARIO NEGRI SUD-CENTRO DI RICERCHE FARMACOLOGICHE EB IOMEDICHE
Organization address
address: Via Nazionale 8/A contact info |
IT (SANTA MARIA IMBARO) | participant | 0.00 |
| 7 |
GOETEBORGS UNIVERSITET
Organization address
address: VASAPARKEN contact info |
SE (GOETEBORG) | participant | 0.00 |
| 8 |
HELSINGIN YLIOPISTO
Organization address
address: YLIOPISTONKATU 4 contact info |
FI (HELSINGIN YLIOPISTO) | participant | 0.00 |
| 9 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
Organization address
address: 101 Rue de Tolbiac contact info |
FR (PARIS) | participant | 0.00 |
| 10 |
INSTITUTE OF SYSTEMS BIOLOGY LTD
Organization address
address: "Krasina Street 54, office 901" contact info |
RU (NOVOSIBIRSK) | participant | 0.00 |
| 11 |
INTEGROMICS SL ITG
Organization address
address: AVENIDA DE INNOVACION GRANADA PARQUE TECNOLOGIA CIENCAS DE LA SALUD 1 BIC contact info |
ES (ARMILLA -GRANADA) | participant | 0.00 |
| 12 |
MAGYAR TUDOMANYOS AKADEMIA SZEGEDI BIOLOGIAI KOZPONTJA
Organization address
address: Temesvari krt. 62 contact info |
HU (SZEGED) | participant | 0.00 |
| 13 |
MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.
Organization address
address: Hofgartenstrasse 8 contact info |
DE (MUENCHEN) | participant | 0.00 |
| 14 |
MEDICAL RESEARCH COUNCIL
Organization address
address: NORTH STAR AVENUE POLARIS HOUSE contact info |
UK (SWINDON) | participant | 0.00 |
| 15 |
PROTAGEN AG
Organization address
address: Otto-Hahn-Strasse 15 contact info |
DE (DORTMUND) | participant | 0.00 |
| 16 |
RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN
Organization address
address: REGINA PACIS WEG 3 contact info |
DE (BONN) | participant | 0.00 |
| 17 |
TECHNISCHE UNIVERSITAET WIEN
Organization address
address: Karlsplatz 13 contact info |
AT (WIEN) | participant | 0.00 |
| 18 |
THE BABRAHAM INSTITUTE
Organization address
address: Babraham Hall contact info |
UK (CAMBRIDGE) | participant | 0.00 |
| 19 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Organization address
address: University Offices, Wellington Square contact info |
UK (OXFORD) | participant | 0.00 |
| 20 |
UNIVERSITAET GRAZ
Organization address
address: UNIVERSITAETSPLATZ 3 contact info |
AT (GRAZ) | participant | 0.00 |
| 21 |
UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS
Organization address
address: Robert-Koch-Strasse 40 contact info |
DE (GOETTINGEN) | participant | 0.00 |
| 22 |
UNIVERSITAT LINZ
Organization address
address: ALTENBERGERSTRASSE 69 contact info |
AT (LINZ) | participant | 0.00 |
| 23 |
UNIVERSITEIT UTRECHT
Organization address
address: Heidelberglaan 8 contact info |
NL (UTRECHT) | participant | 0.00 |
| 24 |
UNIWERSYTET JAGIELLONSKI
Organization address
address: Ul. Golebia 24 contact info |
PL (KRAKOW) | participant | 0.00 |
| 25 |
USTAV EXPERIMENTALNEJ ENDOKRINOLOGIE - SLOVENSKEJ AKADEMIE VIED
Organization address
address: Vlarska 3 contact info |
SK (BRATISLAVA) | participant | 0.00 |
| 26 |
WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER
Organization address
address: SCHLOSSPLATZ 2 contact info |
DE (MUENSTER) | participant | 0.00 |
| 27 |
ZORA BIOSCIENCES LTD
Organization address
address: Biologinkuja 1 contact info |
FI (ESPOO) | participant | 0.00 |
Mappa
Word cloud
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Obiettivo del progetto (Objective)
'Lipids are central to the regulation and control of cellular processes by acting as basic building units for biomembranes, the platforms for the vast majority of cellular functions. Recent developments in lipid mass spectrometry have set the scene for a completely new way to understand the composition of membranes, cells and tissues in space and time by allowing the precise identification and quantification of alterations of the total lipid profile after specific perturbations. In combination with advanced proteome and transcriptome analysis tools and novel imaging techniques using RNA interference, it is now possible to unravel the complex network between lipids, genes and proteins in an integrated lipidomics approach. This project application of the European Lipidomics Initiative (ELife; www.lipidomics.net) will address lipid droplets (LD) as dynamic organelles with regard to composition, metabolism and regulation. LD are the hallmark of energy overload diseases with a major health care impact in Europe. The project will exploit recent advances in lipidomics to establish high-throughput methods to define drugable targets and novel biomarkers related to LD lipid and protein species, their interaction and regulation during assembly, disassembly and storage. Translational research from mouse to man applied to LD pathology is a cornerstone of this project at the interface between research and development. To maximize the value of the assembled data generated throughout the project, “LipidomicNet” as a detailed special purpose Wiki formate data base will be developed and integrated into the existing Lipidomics Expertise Platform (LEP) established through the SSA ELife project (www.lipidomics-expertise.de). ELife collaborates with the NIH initiative LIPID MAPS (www.lipidmaps.org) and the Japanese pendant Lipidbank (www.lipidbank.jp) and is connected to the Danubian Biobank consortium (SSA DanuBiobank, www.danubianbiobank.de) for clinical lipidomics.'
Introduzione (Teaser)
Metabolic overload is a serious problem in developed countries as it is associated with secondary problems, including obesity, type-2 diabetes and atherosclerosis. A European consortium worked to find associations with alterations in the lipid profile and also unravel the complex network of lipids, genes and proteins.
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