MOBVIR

Host mobility and pathogen virulence in host-pathogen interactions: ecology and evolution

Coordinatore	ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE    more  Organization address address: EGHAM HILL UNIVERSITY OF LONDON city: EGHAM postcode: TW20 0EX contact info Titolo: Ms. Nome: Jenny Cognome: Febry Email: send email Telefono: -444759 Fax: +44-1784 475309
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	169˙008 €
EC contributo	169˙008 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2007-2-1-IEF
Funding Scheme	MC-IEF
Anno di inizio	2008
Periodo (anno-mese-giorno)	2008-11-01   -   2010-10-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE  Organization address address: EGHAM HILL UNIVERSITY OF LONDON city: EGHAM postcode: TW20 0EX contact info Titolo: Ms. Nome: Jenny Cognome: Febry Email: send email Telefono: -444759 Fax: +44-1784 475309	UK (EGHAM)	coordinator	0.00

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 Obiettivo del progetto (Objective)

'Pathogens that spread by contact between hosts are highly dependent on the social and spatial contact network of the host population. For human societies, this contact network has dramatically changed over the last century, for instance because of long-distance air travel. In this project, the effects of changes in host mobility patterns on pathogen dynamics will be explored. In particular, the effect of increased host mobility on pathogen virulence (i.e. pathogen-induced loss of host fitness) will be investigated. This project will use innovative mathematical modelling techniques that merge ecological and evolutionary questions into a common framework. Specifically, the project will consider scenarios where the movements of hosts takes place at several spatial scales, and where changes in host movement patterns can occur. The project thus fits into the current growing interest for the evolutionary impact of spatial and social structure in ecology. Ultimately, the project aims at generating testable predictions that can be used to uncover strategies of virulence management that are adapted to the increased mobility of human populations. The results and methods will be applied to meningococcal disease and to an experimental host-parasite system.'