PILGRIM

Preventing community and nosocomial spread and infection with MRSA ST 398 - instruments for accelerated control and integrated risk management of antimicrobial resistance

Coordinatore	THE ROYAL VETERINARY COLLEGE    more  Organization address address: Royal College Street city: LONDON postcode: NW10TU contact info Titolo: Prof. Nome: Katharina Cognome: Stärk Email: send email Telefono: +44 1707 666025 Fax: +44 1707 666574
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	3˙727˙953 €
EC contributo	2˙993˙824 €
Programma	FP7-HEALTH Specific Programme "Cooperation": Health
Code Call	FP7-HEALTH-2007-B
Funding Scheme	CP-FP
Anno di inizio	2009
Periodo (anno-mese-giorno)	2009-01-01   -   2011-12-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	THE ROYAL VETERINARY COLLEGE  Organization address address: Royal College Street city: LONDON postcode: NW10TU contact info Titolo: Prof. Nome: Katharina Cognome: Stärk Email: send email Telefono: +44 1707 666025 Fax: +44 1707 666574	UK (LONDON)	coordinator	0.00
2	ACCELOPMENT AG  Organization address address: SEEFELDSTRASSE 198 city: ZUERICH postcode: 8008 contact info Titolo: Dr. Nome: Jeanette Cognome: Müller Email: send email Telefono: -4556603 Fax: -4556612	CH (ZUERICH)	participant	0.00
3	AGUACURE LIMITED  Organization address address: ALUN ROBERTS BUILDING 9THE FLOOR city: BANGOR postcode: LL57 2UW contact info Nome: John Cognome: Bostock Email: send email Telefono: -389685 Fax: -3885711	UK (BANGOR)	participant	0.00
4	CENTRUM VOOR ONDERZOEK IN DIERGENEESKUNDE EN AGROCHEMIE - CODA  Organization address address: Groeselenberg 99 city: BRUXELLES postcode: 1180 contact info Nome: Eefje Cognome: Tuerlinckx Email: send email Telefono: -3790587 Fax: -3790371	BE (BRUXELLES)	participant	0.00
5	ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM  Organization address address: 's Gravendijkwal 230 city: ROTTERDAM postcode: 3015CE contact info Titolo: Prof. Nome: Henri A. Cognome: Verbrugh Email: send email Telefono: -4633489 Fax: -4633854	NL (ROTTERDAM)	participant	0.00
6	KOBENHAVNS UNIVERSITET	DK	participant	0.00
7	RIJKSINSTITUUT VOOR VOLKSGEZONDHEIDEN MILIEU*NATIONAL INSTITUTEFOR PUBLIC HEALTH AND THE ENVIRONMENTEN  Organization address address: Antonie Van Leeuwenhoeklaan 9 city: BILTHOVEN postcode: 3721 MA contact info Nome: Marjon Cognome: Straver-Hartwigsen Email: send email Telefono: -2747546 Fax: -2744485	NL (BILTHOVEN)	participant	0.00
8	ST GEORGE'S HOSPITAL MEDICAL SCHOOL  Organization address address: Cranmer Terrace city: LONDON postcode: SW17 0RE contact info Titolo: Ms. Nome: Carolyn Cognome: Doughty Email: send email Telefono: -87253492 Fax: -87250770	UK (LONDON)	participant	0.00
9	STATENS SERUM INSTITUT  Organization address address: ARTILLERIVEJ 5 city: KOBENHAVN S postcode: 2300 contact info Titolo: Dr. Nome: Robert Cognome: Skov Email: send email Telefono: -688335 Fax: -683855	DK (KOBENHAVN S)	participant	0.00
10	STICHTING KATHOLIEKE UNIVERSITEIT  Organization address address: GEERT GROOTEPLEIN NOORD 9 city: NIJMEGEN postcode: 6525 EZ contact info Titolo: Mr. Nome: Hendrik-Jan Cognome: Vos Email: send email Telefono: -3618930 Fax: -3540522	NL (NIJMEGEN)	participant	0.00
11	UNIVERSITE LIBRE DE BRUXELLES  Organization address address: Avenue Franklin Roosevelt 50 city: BRUXELLES postcode: 1050 contact info Titolo: Prof. Nome: Philippe Cognome: Vincke Email: send email Telefono: 3225554518 Fax: 3225553110	BE (BRUXELLES)	participant	0.00
12	VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE  Organization address address: TECHNICKA 5 city: PRAHA 6 postcode: 166 28 contact info Titolo: Dr. Nome: Anna Cognome: Mittnerova Email: send email Telefono: -443475 Fax: -443032	CZ (PRAHA 6)	participant	0.00

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 Obiettivo del progetto (Objective)

'Methicillin-resistant Staphylococcus aureus (MRSA) are of increasing concern both as community- and hospital-acquired pathogens. Since 2005, a specific clone, MRSA ST398 is spreading both in livestock populations and occupationally-exposed people resulting in human infection and disease in several EU Member States. The key objective of the PILGRIM project is to provide a range of novel control measures for the accelerated identification and control of emerging resistant bacteria. In order to achieve these we will undertake epidemiological and physiological studies of MRSA ST398 and use molecular approaches in well comparable animal models as well as humans in community and healthcare settings to 1) investigate/explore its biology and ecology, 2) identify and characterise factors determining the transmission pathways and risk from animal to human and between humans, 3) establish genetic differences, host-range and virulence of adhesive and non-adhesive strains as well as differences between ST398 and other MRSA, 3) identify specific genes for the development of new rapid tests to identify specific MRSA strains, 4) provide a Technology Testing Platform for developing and assessing decolonisation and environmental sanitation approaches, 5) integrate results in policy and practice guidelines. This project brings together clinical, genetic, microbiological and public health partners from 6 European countries, internationally renowned for their expertise in complementary ecosystems research. The two SME partners ensure the exploitation of results and the knowledge transfer, enabling associated companies to bring validated solutions to the market. The PILGRIM research will facilitate rapid and cost-effective measures to combat emerging resistant strains in order to prevent and eradicate community and nosocomial infections for better protection of citizens and patients in Europe and beyond.'