ENEFP
European Network on Directed Evolution of Functional Proteins
| Coordinatore | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Organization address
address: The Old Schools, Trinity Lane contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Totale costo | 2˙400˙000 € |
| EC contributo | 2˙400˙000 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-2007-1-1-ITN |
| Funding Scheme | MC-ITN |
| Anno di inizio | 2008 |
| Periodo (anno-mese-giorno) | 2008-10-15 - 2012-10-14 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Organization address
address: The Old Schools, Trinity Lane contact info |
UK (CAMBRIDGE) | coordinator | 0.00 |
| 2 |
Nome Ente NON disponibile
Organization address
address: Domstrasse 11 contact info |
DE (GREIFSWALD) | participant | 0.00 |
| 3 |
BEN-GURION UNIVERSITY OF THE NEGEV
Organization address
address: Office of the President - Main Campus contact info |
IL (BEER SHEVA) | participant | 0.00 |
| 4 |
Biotechnology Research And Information Network Aktiengesellschaft
Organization address
city: Zwingenberg contact info |
DE (Zwingenberg) | participant | 0.00 |
| 5 |
COVALYS BIOSCIENCES AG
Organization address
address: Benkenstrasse 254 contact info |
CH (Witterswil) | participant | 0.00 |
| 6 |
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Organization address
address: BATIMENT CE 3316 STATION 1 contact info |
CH (LAUSANNE) | participant | 0.00 |
| 7 |
MEDIMMUNE LIMITED*
Organization address
address: The Milstein Building Granta Park contact info |
UK (Cambridge) | participant | 0.00 |
| 8 |
RIJKSUNIVERSITEIT GRONINGEN
Organization address
address: Broerstraat 5 contact info |
NL (GRONINGEN) | participant | 0.00 |
| 9 |
UNIVERSITE CATHOLIQUE DE LOUVAIN
Organization address
address: Place De L'Universite 1 contact info |
BE (LOUVAIN LA NEUVE) | participant | 0.00 |
| 10 |
UNIVERSITE DE STRASBOURG
Organization address
address: rue Blaise Pascal 4 contact info |
FR (Strasbourg) | participant | 0.00 |
Mappa
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Obiettivo del progetto (Objective)
'This project intends to use directed evolution as tool to reproduce Nature's remarkable ability to generate molecular machines - in particular enzymes – that perform at levels near perfection. By harnessing the forces of Darwinian evolution in the laboratory we want to (i) screen large and diverse genome libraries for protein with new and useful functions, (ii) optimize existing proteins for applications in medicine, biotechnology and cell biology and (iii) provide a better understanding of how existing enzymes evolved and study enzyme mechanisms in general. The proposed Network brings together leading academic and industrial groups with diverse and complementary skills: the development of a variety of innovative biotechnology tools for the generation and exploitation of large genomic and man-made libraries, expertise in mechanistic enzymology and an unrivalled technology platform including phage display, in vitro compartmentalization, ribosome display, selective protein labelling and high-throughput screening that will be key to achieve the ambitious goals of this project. The project is a continuation of a highly successful framework 5 network. The partnership has now been extended by two successful SMEs at different stages of their development and one of Europe’s premier medium-sized biotech companies that are keen to utilise and market the expected results of this collaborative effort.'