TRANSCOM
The Commercialisation of Transglutaminase
| Coordinatore | ASTON UNIVERSITY
Organization address
address: ASTON TRIANGLE contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Totale costo | 1˙680˙248 € |
| EC contributo | 1˙680˙248 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-2009-IAPP |
| Funding Scheme | MC-IAPP |
| Anno di inizio | 2010 |
| Periodo (anno-mese-giorno) | 2010-07-01 - 2014-06-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
ASTON UNIVERSITY
Organization address
address: ASTON TRIANGLE contact info |
UK (BIRMINGHAM) | coordinator | 582˙165.00 |
| 2 |
TAMPEREEN YLIOPISTO
Organization address
address: Kalevantie 4 contact info |
FI (TAMPERE) | participant | 284˙064.00 |
| 3 |
X-Link Limited
Organization address
address: "Biocity Nottingham, Pennyfoot Street" contact info |
UK (Nottingham) | participant | 210˙941.00 |
| 4 |
COVALAB SAS
Organization address
address: AVENUE ALBERT EINSTEIN 11 contact info |
FR (VILLEURBANNE) | participant | 193˙781.00 |
| 5 |
Ani Biotech Oy
Organization address
address: Museokatu 13B contact info |
FI (Helsinki) | participant | 170˙239.00 |
| 6 |
DEBRECENI EGYETEM
Organization address
address: EGYETEM TER 1 contact info |
HU (DEBRECEN) | participant | 144˙286.00 |
| 7 |
UD-GENOMED MEDICAL GENOMIC TECHNOLOGIES KUTATAS-FEJLESZTESI ES SZOLGALTATO KFT
Organization address
address: NAGYERDEI KRT 98 contact info |
HU (DEBRECEN) | participant | 94˙772.00 |
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Obiettivo del progetto (Objective)
'The TRANSCOM project is designed to facilitate the exchange of knowledge and technology between 3 leading European research teams and 4 SMEs each with an interest in the protein crosslinking enzymes Transglutaminases. Transglutaminases are a widely distributed group of enzymes that catalyse the post-translational modification of proteins by the formation of isopeptide bonds or by deamidation of proteins. The deregulation of enzyme activity generally associated with major disruptions in cellular/tissue homeostasis can result in a number of human diseases TRANSCOM will be involved in the invention, development and production of diagnostic kits and treatments for health problems related to the activity of transglutaminases. The project will establish the molecular nature of the role of transglutaminases in the pathogenesis of diseases such as coeliac disease, neurodegeneration and intravenous catheter infections which are known to involve their cross-linking activity. The proposed work programme will develop new knowledge to address gaps in our understanding of this field and transfer existing knowledge and skills between sectors. It will build and broaden the capability of the partners with the objective of accelerating the development of new strategies that can be used in diagnosis and treatment of coeliac disease, neurodegeneration and in the prevention of infections like MRSA associated with intravenous catheters.'