ARABIGANS

Uncovering conserved proliferation pathways between plants and animals

Coordinatore	UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE    more  Organization address address: AVENIDA DE LA UNIVERSIDAD S/N city: ELCHE postcode: 3202 contact info Titolo: Mrs. Nome: Emma Cognome: Benlloch-Marco Email: send email Telefono: +34 966 658 613 Fax: +34 966 658 666
Nazionalità Coordinatore	Spain [ES]
Totale costo	100˙000 €
EC contributo	100˙000 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2009-RG
Funding Scheme	MC-IRG
Anno di inizio	2010
Periodo (anno-mese-giorno)	2010-09-01   -   2014-08-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE  Organization address address: AVENIDA DE LA UNIVERSIDAD S/N city: ELCHE postcode: 3202 contact info Titolo: Mrs. Nome: Emma Cognome: Benlloch-Marco Email: send email Telefono: +34 966 658 613 Fax: +34 966 658 666	ES (ELCHE)	coordinator	100˙000.00

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 Obiettivo del progetto (Objective)

'The study of plant biology is useful in two ways. Under a basic research perspective, it yields basic knowledge on processes that are specific to plants and distinguish them from animals. From an applied perspective, this knowledge can lead to an improvement in the quality or the productivity of crops. Any given aspect of plant biology can be considered to be fully dissected only after the genes that control it have been identified, which makes its eventual controlled perturbation possible. Plant genetic research can also help to understand the conserved functions of such genes in different organisms as well as to establish their biotechnological potential. In this proposal, I aim (1) to identify genes important for leaf morphogenesis in the model plant Arabidopsis thaliana, as inferred from the effects of their loss of function on cell size and cell number; (2) to characterize the effects of their constitutive expression in Arabidopsis thaliana, in order to assess their potential application as plant growth modulators; (3) to characterize the effects of their heterologous expression in an animal model system (Caenorhabditis elegans), in order to assess their potential pharmacological use and the eventual conservation of their functions in the control of cell proliferation; and (4) to knock down the putative orthologs of these genes in Caenorhabditis, in an attempt to establish their potential use as regulators of cell proliferation.'

Introduzione (Teaser)

Researchers have investigated cell proliferation pathways involved in plant leaf development in an attempt to establish cell growth mechanisms shared between plants and animals.