BACMT

Functional and structural analysis of bacterial membrane transporters

Coordinatore	UNIVERSITETET I OSLO    more  Organization address address: Problemveien 5-7 city: OSLO postcode: 313 contact info Titolo: Prof. Nome: Rigmor Cognome: Bjorkli Email: send email Telefono: +47 22856586 Fax: +47 22854402
Nazionalità Coordinatore	Norway [NO]
Totale costo	59˙400 €
EC contributo	59˙400 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2009-IRSES
Funding Scheme	MC-IRSES
Anno di inizio	2010
Periodo (anno-mese-giorno)	2010-09-03   -   2014-09-02

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	UNIVERSITETET I OSLO  Organization address address: Problemveien 5-7 city: OSLO postcode: 313 contact info Titolo: Prof. Nome: Rigmor Cognome: Bjorkli Email: send email Telefono: +47 22856586 Fax: +47 22854402	NO (OSLO)	coordinator	39˙600.00
2	UNIVERSITY OF LEEDS  Organization address address: WOODHOUSE LANE city: LEEDS postcode: LS2 9JT contact info Titolo: Ms. Nome: Kathy Cognome: Brownridge Email: send email Telefono: +44 113 34 36050 Fax: +44 113 34 34058	UK (LEEDS)	participant	19˙800.00

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 Obiettivo del progetto (Objective)

'Membrane transport proteins play crucial roles in fundamental cellular processes and functions in all organisms. A substantial proportion of prokaryotic genes are predicted to encode membrane transporters, emphasising the importance of transporters in their lifestyles. In silico analysis of sequenced Acinetobacter baumannii and Bacillus cereus group strains has revealed the presence of an unprecedented high number (over 100) of multidrug resistance (MDR) efflux pumps in these pathogenic bacteria. The current project is a collaboration between three partners, two European and an Australian research group. The project aims to increase our knowledge about the membrane transport processes with regards to their role in microbial pathogenesis and resistance to antimicrobials. The project also aims to illuminate the evolutionary relatedness and structure-function relationships of membrane transport proteins.'