PHARMAGEN

Innovative multidisciplinary approach to pharma generic production

Coordinatore	SERICHIM S.r.l.    more  Organization address address: Piazzale Marinotti 1 city: Torviscosa postcode: 33050 contact info Titolo: Dr. Nome: Fausto Cognome: Ferrazzi Email: send email Telefono: +39 0431 381415 Fax: +39 0431 381400
Nazionalità Coordinatore	Italy [IT]
Totale costo	1˙496˙765 €
EC contributo	1˙041˙612 €
Programma	FP7-SME Specific Programme "Capacities": Research for the benefit of SMEs
Code Call	FP7-SME-2008-1
Funding Scheme	BSG-SME
Anno di inizio	2009
Periodo (anno-mese-giorno)	2009-05-01   -   2011-04-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	SERICHIM S.r.l.  Organization address address: Piazzale Marinotti 1 city: Torviscosa postcode: 33050 contact info Titolo: Dr. Nome: Fausto Cognome: Ferrazzi Email: send email Telefono: +39 0431 381415 Fax: +39 0431 381400	IT (Torviscosa)	coordinator	73˙694.00
2	FLAMMA  Organization address address: via Bedeschi 22 city: Chignolo d'isola postcode: 24040 contact info Titolo: Dr. Nome: Rossella Cognome: Padroncelli Email: send email Telefono: +39 035 499 1811 Fax: +39 035 499 1812	IT (Chignolo d'isola)	participant	351˙447.50
3	Carbopharm GmbH  Organization address address: Industriestrasse 10 city: Lannach postcode: 8502 contact info Titolo: Dr. Nome: Chirstian Cognome: Jucker Email: send email Telefono: +43 313683083 Fax: +43 313683083	AT (Lannach)	participant	230˙210.90
4	APOTECNIA S.A.  Organization address address: Carretera de Zeneta 149 city: Murcia postcode: 30588 contact info Titolo: Dr. Nome: Trinidad Cognome: Pedro Email: send email Telefono: +34 968854266 Fax: +34 968854361	ES (Murcia)	participant	223˙201.80
5	FLAMMA S.P.A.  Organization address address: VIA BEDESCHI 22 city: CHIGNOLO D ISOLA postcode: 24040 contact info Titolo: Dr. Nome: Rossella Cognome: Pedroncelli Email: send email Telefono: +39 035 499 1811 Fax: +39 035 499 1812	IT (CHIGNOLO D ISOLA)	participant	88˙325.00
6	MERCHAV ENGINEERING LTD  Organization address address: FRIESCHMAN ST 33 city: KIRYAT ATA postcode: 28110 contact info Titolo: Mr. Nome: Zvi Cognome: Merchav Email: send email Telefono: +972 4 8454428 Fax: +972 4 8454429	IL (KIRYAT ATA)	participant	58˙220.80
7	Process Systems Enterprise Ltd  Organization address address: "6th Floor East, Hammersmith Bridge Road 26-28" city: London postcode: W6 7HA contact info Titolo: Prof. Nome: Nilay Cognome: Shah Email: send email Telefono: +44 20 8563 0888 Fax: +44 20 8563 0999	UK (London)	participant	6˙528.00
8	licensing development and trading international s.r.l.  Organization address address: Via Camperio 9 city: milano postcode: 20123 contact info Titolo: Dr. Nome: Garavaglia Cognome: Antonio Email: send email Telefono: +39 338 6006038	IT (milano)	participant	5˙664.00
9	Ashe Morris Ltd  Organization address address: "AGP, Sterling House, Centre Park" city: Warrington postcode: WA1 1GG contact info Titolo: Mr. Nome: Ashe Cognome: Robert Email: send email Telefono: +44 2083874134 Fax: +44 2082084137	UK (Warrington)	participant	4˙320.00

Mappa

 Word cloud

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 Obiettivo del progetto (Objective)

'The motivation of PHARMAGEN stems from a recognition that bulk Active Pharmaceutical Ingredients (API) manufacturers need to employ new synthesis routes and better manufacturing techniques for the manufacture of generics drugs. It is also recognised that a key enabling technology for achieving this goal entails greater use of continuous processes. A successful outcome will deliver processes which are more energy efficient, have higher yields, better controllability and quality, greater flexibility of output and faster development time. Most importantly, development of effective continuous processing methods will give European manufacturers a significant competitive advantage over Asian producers who have been progressively eroding the European know how and market share leadership in the API market. The PHARMAGEN project aims to improve the competitiveness of the participants by developing continuous production routes for three specific APIs selected by the SMEs. Batch pharmaceutical processes and continuous petrochemicals source their raw materials from the same basic chemical pool. Despite this, yield indexes (= wt reactants/wt final product, representing the effectiveness of the processes) for high throughput plants are typically in the region of 1,2 - 1,5, compared to more 10, for pharmaceutical batch processes. Thus, traditional pharmaceutical processes are characterised by waste levels of 90% plus. The PHARMAGEN project will allow participating SMEs to develop new and better chemical synthesis methods based on continuous processing. Further innovative modelling and process control will be developed. This will give European pharmaceuctical manufacturers a competitive advantage. Continuous processes can allow very high control level respect discontinuous ones, and this aspect is of paramount value for quality assurance in the manufacture of products for the human consumption.'