NEUROSCHEMA

The neurobiology of schemas: knowledge acquisition and consolidation

 Coordinatore THE UNIVERSITY OF EDINBURGH 

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 Nazionalità Coordinatore United Kingdom [UK]
 Totale costo 3˙051˙404 €
 EC contributo 3˙051˙404 €
 Programma FP7-IDEAS-ERC
Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call ERC-2010-AdG_20100317
 Funding Scheme ERC-AG
 Anno di inizio 2011
 Periodo (anno-mese-giorno) 2011-06-01   -   2016-05-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    STICHTING KATHOLIEKE UNIVERSITEIT

 Organization address address: GEERT GROOTEPLEIN NOORD 9
city: NIJMEGEN
postcode: 6525 EZ

contact info
Titolo: Mr.
Nome: Maarten
Cognome: Van Langen
Email: send email
Telefono: +31 24 3619791
Fax: +31 24 3540529

NL (NIJMEGEN) beneficiary 1˙188˙291.90
2    THE UNIVERSITY OF EDINBURGH

 Organization address address: OLD COLLEGE, SOUTH BRIDGE
city: EDINBURGH
postcode: EH8 9YL

contact info
Titolo: Ms.
Nome: Angela
Cognome: Noble
Email: send email
Telefono: +44 131 650 9024
Fax: +44 131 651 4028

UK (EDINBURGH) hostInstitution 1˙863˙112.10
3    THE UNIVERSITY OF EDINBURGH

 Organization address address: OLD COLLEGE, SOUTH BRIDGE
city: EDINBURGH
postcode: EH8 9YL

contact info
Titolo: Prof.
Nome: Richard Graham Michael
Cognome: Morris
Email: send email
Telefono: +44 131 650 3518
Fax: +44 131 651 1835

UK (EDINBURGH) hostInstitution 1˙863˙112.10

Mappa


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upon    rapid    prior    iquest    traces    magnetic    cognitive    novelty    declarative    neural    mechanisms    memory    neurobiological    schemas    consolidation    learning    associative   

 Obiettivo del progetto (Objective)

'This Co-Investigator Application is an interdisciplinary experimental analysis of the neurobiological mechanisms by which we acquire knowledge. Our approach builds on the foundations of contemporary cognitive neuroscience, particularly ideas about the neural mechanisms of declarative memory, and upon recent findings of the participating laboratories (Morris, Fernández) that have each addressed key issues associated with the rapid acquisition and assimilation of new associative information into existing neural ¿schemas¿. Rapid learning depends upon both novelty and prior knowledge. We propose a coordinated program of research concerning the mechanisms of both determinants. First, we will test that novelty, acting via the release of dopamine, has a direct impact on the mechanisms of cellular consolidation in the hippocampus. Second, with respect to prior knowledge, the retention of new event-related associative information requires the process of systems consolidation within declarative memory, as widely studied, but we further suggest that the organisation of knowledge requires more than just stabilising memory traces within neocortical networks. It also involves the integration of distinct memory traces into neural ¿schemas¿ that, once formed, have a major positive influence on future learning. Our experiments to date are supportive and we outline new research to examine the neurobiological basis of schemas. This will involve animal experimentation including novel behavioural tasks, optogenetics and single-cell recording; and functional magnetic resonance imaging of the human brain using new cognitive tasks combined with pharmacology, transcranial magnetic stimulation, model-free analysis methods, and a translational project reaching into real-world education.'

Altri progetti dello stesso programma (FP7-IDEAS-ERC)

SIMPLELCGPS (2011)

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ACTMECH (2011)

Emergent Active Mechanical Behaviour of the Actomyosin Cell Cortex

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NEUROCHEMS (2009)

From neurons to behavior: analysis of the mechanisms underlying sensory coding and plasticity in chemical senses

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