REINFORCE

Inflammatory Bowel Disease: an EU-NZ integrated approach for characterizing its molecular multifactorial mechanisms

Coordinatore	ALMA MATER STUDIORUM-UNIVERSITA DI BOLOGNA    more  Organization address address: Via Zamboni 33 city: BOLOGNA postcode: 40126 contact info Titolo: Prof. Nome: Patrizia Cognome: Brigidi Email: send email Telefono: +39 051 2099743 Fax: +39 051 2099734
Nazionalità Coordinatore	Italy [IT]
Totale costo	536˙300 €
EC contributo	344˙400 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2010-IRSES
Funding Scheme	MC-IRSES
Anno di inizio	2012
Periodo (anno-mese-giorno)	2012-01-01   -   2014-12-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	ALMA MATER STUDIORUM-UNIVERSITA DI BOLOGNA  Organization address address: Via Zamboni 33 city: BOLOGNA postcode: 40126 contact info Titolo: Prof. Nome: Patrizia Cognome: Brigidi Email: send email Telefono: +39 051 2099743 Fax: +39 051 2099734	IT (BOLOGNA)	coordinator	69˙300.00
2	UNIVERSITY OF EAST ANGLIA  Organization address address: EARLHAM ROAD city: NORWICH postcode: NR4 7TJ contact info Titolo: Ms. Nome: Sue Cognome: Steel Email: send email Telefono: +4401603 591486 Fax: +4401603 591550	UK (NORWICH)	participant	71˙400.00
3	WAGENINGEN UNIVERSITY  Organization address address: DROEVENDAALSESTEEG 4 city: WAGENINGEN postcode: 6708 PB contact info Titolo: Mr. Nome: Tom Cognome: Bessems Email: send email Telefono: +31 317 484478 Fax: +31 317 483342	NL (WAGENINGEN)	participant	71˙400.00
4	INSTITUT CATALA DE LA SALUT  Organization address address: GRAN VIA DE LES CORTS CATALANES 587 city: BARCELONA postcode: 8007 contact info Titolo: Mr. Nome: Lluis Cognome: Masso Email: send email Telefono: +34 934894200 Fax: +34 934894102	ES (BARCELONA)	participant	69˙300.00
5	MEDIZINISCHE UNIVERSITAET INNSBRUCK  Organization address address: Christoph-Probst Platz 1 city: INNSBRUCK postcode: 6020 contact info Titolo: Dr. Nome: Herbert Cognome: Tilg Email: send email Telefono: +43 512 50423374 Fax: +43 512 50423177	AT (INNSBRUCK)	participant	63˙000.00

Mappa

 Word cloud

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 Obiettivo del progetto (Objective)

'Over the past 20 years there has been a dramatic rise in the incidence of Inflammatory bowel disease (IBD), both in EU and NZ. IBD refers primarily to two major disorders such as ulcerative colitis (UC) and Crohn's disease (CD), chronic conditions characterized by inflammatory lesions involving gut mucosa. CD is also an emerging problem amongst children. Etiology of IBD is still unknown, however several studies demonstrate multifactorial mechanisms contributing to its pathogenesis (i.e. immunoregulatory defects, genetic mutations, dysbiosis of commensal enteric microbiota, alterations in mucosal permeability, alimentary factors). The complexity of these factors makes necessary for a researcher to acquire the widest spectrum of advanced techniques enabling the deeper understanding of IBD onset and recurrence and developing useful therapeutic strategies. Both Eu and NZ have significantly contribute to IBD research advances, by developing outstanding research expertise and being equipped with the most advance methodological tools. REINFORCE consortium is a multidisciplinary scientific network, in which each partner is a leader in IBD mechanisms. The high level of synergies within REINFORCE consortium, highlighting the cross-talk among different disciplines, will provide a multidisciplinary training for EU and NZ researchers. This joint exchange programme represents a unique opportunity to lead to a high degree of novelty in IBD training by allowing to build up a new profile of researcher able to tackle the different aspects of IBD. REINFORCE has settled down a series of specific and technical objectives which will guarantee the ESRs and ERs to be provided with training tools ensuring the use of the most advanced molecular and cellular techniques. Training modules will concern: (i) IBD Modulation of Immune response, (ii) IBD Characterization and modulation of gut microbiota, (iii) IBD intestinal epithelial barrier, (iv) Nutrition and genetics on IBD.'

Introduzione (Teaser)

Irritable bowel disease (IBD) is a condition that affects the large intestine and presents with variable symptoms such as abdominal pain and discomfort. Researchers from the EU and New Zealand teamed up to investigate IBD origins and provide improved and integrated treatment protocols.