BonePain
European Training Network on Bone Pain
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0BonePain project word cloud
Explore the words cloud of the BonePain project. It provides you a very rough idea of what is the project "BonePain" about.
Project "BonePain" data sheet
The following table provides information about the project.
| Coordinator |
KOBENHAVNS UNIVERSITET
Organization address contact info |
| Coordinator Country | Denmark [DK] |
| Project website | http://www.bonepain.eu |
| Total cost | 3˙558˙676 € |
| EC max contribution | 3˙558˙676 € (100%) |
| Programme |
1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers) |
| Code Call | H2020-MSCA-ITN-2014 |
| Funding Scheme | MSCA-ITN-ETN |
| Starting year | 2015 |
| Duration (year-month-day) | from 2015-01-01 to 2018-12-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | KOBENHAVNS UNIVERSITET | DK (KOBENHAVN) | coordinator | 580˙163.00 |
| 2 | UNIVERSITY COLLEGE LONDON | UK (LONDON) | participant | 819˙863.00 |
| 3 | NORDIC BIOSCIENCE A/S | DK (HERLEV) | participant | 580˙163.00 |
| 4 | THE ROYAL VETERINARY COLLEGE | UK (LONDON) | participant | 546˙575.00 |
| 5 | KAROLINSKA INSTITUTET | SE (STOCKHOLM) | participant | 527˙318.00 |
| 6 | UNIVERSITAIR MEDISCH CENTRUM UTRECHT | NL (UTRECHT) | participant | 255˙374.00 |
| 7 | GRUNENTHAL GMBH | DE (AACHEN) | participant | 249˙216.00 |
| 8 | NORDIC BIOSCIENCE COMPOUND DEVELOPMENT A/S | DK (Helev) | participant | 0.00 |
| 9 | TRANSPHARMATION LTD | UK (LONDON) | partner | 0.00 |
Map
Project objective
The aim is to create an innovative European PhD training network in bone pain. Millions in Europe and beyond suffer from bone pain, a debilitating complication of many musculoskeletal disorders such as arthritis and bone metastasis. However, being a truly multidisciplinary subject spanning neuroscience, bone biology, and even cancer research, it demands a multidisciplinary approach. Despite a huge negative impact on the quality of life of the patients and on society as a whole, no specific treatment is available. To address this societal challenge and the strong innovation potential, we want to form the first European platform to promote frontline research, innovation and education within bone pain. The network encompasses 5 academic and 2 industrial beneficiaries and 1 industrial partner all committed to creating an outstanding wide-ranging yet integrated training program for early stages researchers to elucidate the mechanisms of bone pain and develop new medicines. We will use in vivo models of arthritic pain, cancer-induced bone pain and fracture pain to investigate the pathophysiology and novel treatment strategies. In vivo electrophysiology will be used for studying the physiology and pharmacology of pain transmission and its modulation. Transgenic mouse models will be used to tease out the specific neuronal receptor subtypes involved. Sophisticated behaviour tests will evaluate response to novel treatments. We will create a biobank of human cancer-infiltrated bone to identify specific patterns of neuronal receptor expression and to validate therapeutic targets in humans. In an extensive training effort covering both specific research skills and transferable skills, the students will obtain an interdisciplinary, state-of-the-art and innovative training from the participants, several of which have experience from international networks. The students will benefit from secondments with industrial partners and with some of the foremost pain researchers in Europe
Deliverables
| Degree Award | Documents, reports | 2020-01-20 16:54:37 |
| Public outreach | Other | 2020-01-20 16:54:37 |
| Papers | Other | 2020-01-20 16:54:37 |
| Website (2) | Websites, patent fillings, videos etc. | 2020-01-20 16:54:37 |
| Dissemination training | Other | 2020-01-20 16:54:37 |
| International aspect | Other | 2020-01-20 16:54:37 |
| Midterm review Meeting | Documents, reports | 2020-01-20 16:54:36 |
| Recruitment | Other | 2020-01-20 16:54:36 |
| Website (1) | Websites, patent fillings, videos etc. | 2020-01-20 16:54:36 |
| Ethics | Documents, reports | 2020-01-20 16:54:36 |
Take a look to the deliverables list in detail: detailed list of BonePain deliverables.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2017 |
Ramin Raoof, Hanneke L D M Willemen, Niels Eijkelkamp Divergent roles of immune cells and their mediators in pain published pages: 429-440, ISSN: 1462-0324, DOI: 10.1093/rheumatology/kex308 |
Rheumatology 57/3 | 2020-01-20 |
| 2019 |
Teresa Fernandez-Zafra, Tianle Gao, Alexandra Jurczak, Katalin Sandor, Zoe Hore, Nilesh M. Agalave, Jie Su, Johanna Estelius, Jon Lampa, Tomas Hokfelt, Zsuzsanna Wiesenfeld-Hallin, Xiaojun Xu, Franziska Denk, Camilla I. Svensson Exploring the transcriptome of resident spinal microglia after collagen antibody–induced arthritis published pages: 224-236, ISSN: 0304-3959, DOI: 10.1097/j.pain.0000000000001394 |
PAIN 160/1 | 2020-01-20 |
| 2018 |
M.A. Bangash, Sascha R.A. Alles, Sonia Santana-Varela, Queensta Millet, Shafaq Sikandar, Larissa de Clauser, Freija ter Heegde, Abdella M. Habib, Vanessa Pereira, Jane E. Sexton, Edward C. Emery, Shengnan Li, Ana P. Luiz, Janka Erdos, Samuel J. Gossage, Jing Zhao, James J. Cox, John N. Wood Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditions published pages: 78, ISSN: 2398-502X, DOI: 10.12688/wellcomeopenres.14641.1 |
Wellcome Open Research 3 | 2020-01-20 |
| 2018 |
Ryan Patel, Carlota Montagut-Bordas, Anthony H Dickenson Calcium channel modulation as a target in chronic pain control published pages: 2173-2184, ISSN: 0007-1188, DOI: 10.1111/bph.13789 |
British Journal of Pharmacology 175/12 | 2020-01-20 |
| 2018 |
Marta Diaz-delCastillo, David P.D. Woldbye, Anne Marie Heegaard Neuropeptide Y and its Involvement in Chronic Pain published pages: 162-169, ISSN: 0306-4522, DOI: 10.1016/j.neuroscience.2017.08.050 |
Neuroscience 387 | 2020-01-20 |
| 2019 |
Freija ter Heegde, Ana P. Luiz, Sonia Santana-Varela, Iain P. Chessell, Fraser Welsh, John N. Wood, Chantal Chenu Non-invasive mechanical joint loading as an alternative model for osteoarthritic pain published pages: , ISSN: 2326-5191, DOI: 10.1002/art.40835 |
Arthritis & Rheumatology | 2020-01-20 |
| 2017 |
Maja R. RadojÄić, Christian S. Thudium, Kim Henriksen, Keith Tan, Rolf Karlsten, Amanda Dudley, Iain Chessell, Morten A. Karsdal, Anne-Christine Bay-Jensen, Michel D. Crema, Ali Guermazi Biomarker of extracellular matrix remodelling C1M and proinflammatory cytokine interleukin 6 are related to synovitis and pain in end-stage knee osteoarthritis patients published pages: 1254-1263, ISSN: 0304-3959, DOI: 10.1097/j.pain.0000000000000908 |
PAIN 158/7 | 2020-01-20 |
| 2017 |
Camilla Kristine Appel, Simone Gallego-Pedersen, Line Andersen, Sophie Blancheflor Kristensen, Ming Ding, Sarah Falk, Manasi Sayilekshmy, Charlotte Gabel-Jensen, Anne-Marie Heegaard The Src family kinase inhibitor dasatinib delays pain-related behaviour and conserves bone in a rat model of cancer-induced bone pain published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-017-05029-1 |
Scientific Reports 7/1 | 2020-01-20 |
| 2017 |
Kirsty Bannister, Mateusz Kucharczyk, Anthony H. Dickenson Hopes for the Future of Pain Control published pages: 117-128, ISSN: 2193-8237, DOI: 10.1007/s40122-017-0073-6 |
Pain and Therapy 6/2 | 2020-01-20 |
| 2019 |
Anna Katri, Aneta Dąbrowska, Henrik Löfvall, Ming Ding, Morten A. Karsdal, Kim V. Andreassen, Christian S. Thudium, Kim Henriksen Combining naproxen and a dual amylin and calcitonin receptor agonist improves pain and structural outcomes in the collagen-induced arthritis rat model published pages: , ISSN: 1478-6362, DOI: 10.1186/s13075-019-1819-9 |
Arthritis Research & Therapy 21/1 | 2020-01-20 |
| 2019 |
Ryan Patel, Mateusz Kucharczyk, Carlota Montagut-Bordas, Stevie Lockwood, Anthony H. Dickenson Neuropathy following spinal nerve injury shares features with the irritable nociceptor phenotype: A back-translational study of oxcarbazepine published pages: 183-197, ISSN: 1090-3801, DOI: 10.1002/ejp.1300 |
European Journal of Pain 23/1 | 2020-01-20 |
| 2018 |
Emerson Krock, Alexandra Jurczak, Camilla I. Svensson Pain pathogenesis in rheumatoid arthritis—what have we learned from animal models? published pages: S98-S109, ISSN: 0304-3959, DOI: 10.1097/j.pain.0000000000001333 |
PAIN 159 | 2020-01-20 |
| 2016 |
Bas DB, Rudjito R, Wigerblad G, Su Jie and Svensson CI Involvement of inflammatory mediators in arthritis-induced pain:what do experimental models tell us? published pages: , ISSN: , DOI: |
Ch. 21. Pain 2016: Refresher course, 16th World Congress on Pain | 2020-01-20 |
| 2018 |
Marta Diaz-delCastillo, Søren H. Christiansen, Camilla K. Appel, Sarah Falk, David P.D. Woldbye, Anne-Marie Heegaard Neuropeptide Y is Up-regulated and Induces Antinociception in Cancer-induced Bone Pain published pages: 111-119, ISSN: 0306-4522, DOI: 10.1016/j.neuroscience.2018.05.025 |
Neuroscience 384 | 2020-01-20 |
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "BONEPAIN" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "BONEPAIN" are provided by the European Opendata Portal: CORDIS opendata.