Explore the words cloud of the InCeM project. It provides you a very rough idea of what is the project "InCeM" about.
The following table provides information about the project.
Coordinator |
UNIVERSITAETSKLINIKUM AACHEN
Organization address contact info |
Coordinator Country | Germany [DE] |
Project website | https://incem.rwth-aachen.de |
Total cost | 3˙866˙665 € |
EC max contribution | 3˙866˙665 € (100%) |
Programme |
1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers) |
Code Call | H2020-MSCA-ITN-2014 |
Funding Scheme | MSCA-ITN-ETN |
Starting year | 2015 |
Duration (year-month-day) | from 2015-01-01 to 2018-12-31 |
Take a look of project's partnership.
Cell migration (cell motility) is a fundamental biological process that is pivotal in (i) tissue formation and repair (health) and (ii) tissue invasion during carcinogenesis (disease). Understanding and controlling cell migration will have major clinical impact. Clarifying mechanisms driving cell motility has been challenging due to the complex underlying cellular mechanisms; these involve multiple components coordinated by structural, chemical and physical signals in terms of time and space. To accomplish breakthroughs in this field, researchers are needed who (i) master cutting-edge experimental techniques for monitoring the different cellular processes at high resolution and (ii) have competencies in theoretical science for integrating the resulting data sets into mechanistic mathematical models for predicting motile cell behaviour. The Research Training Network on Integrated Component Cycling in Epithelial Cell Motility (InCeM) aims to endow up-and-coming researchers with exactly these competencies. They will be able to develop and apply innovative devices for microscopic recording, image processing techniques, data analysis tools and modelling procedures for mechanistic understanding of cell migration. InCeM will focus on epithelial cells, since inducing motility in this cell type is clinically relevant for wound healing and cancer invasion. The ultimate goal is to control and manipulate cell migration for clinical applications. A dedicated multidisciplinary team of 11 beneficiaries from universities (4), research institutions (4) and industry (3), based in 5 European countries and Israel, together with 17 associated partners from the public and private sector, will train 15 Early Stage Researchers (ESRs) to use the relevant technologies and sciences and will offer business training to prepare them for successful careers in both academic and non-academic environments.
PhD theses | Documents, reports | 2019-07-10 14:42:08 |
Sustainability | Documents, reports | 2019-07-10 14:42:08 |
Communication 1 | Documents, reports | 2019-07-10 14:42:08 |
Communication | Documents, reports | 2019-07-10 14:42:08 |
Take a look to the deliverables list in detail: detailed list of InCeM deliverables.
year | authors and title | journal | last update |
---|---|---|---|
2018 |
D. J. Huels, L. Bruens, M. C. Hodder, P. Cammareri, A. D. Campbell, R. A. Ridgway, D. M. Gay, M. Solar-Abboud, W. J. Faller, C. Nixon, L. B. Zeiger, M. E. McLaughlin, E. Morrissey, D. J. Winton, H. J. Snippert, J. van Rheenen, O. J. Sansom Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells published pages: Article number 1, ISSN: 2041-1723, DOI: 10.1038/s41467-018-03426-2 |
Nature Communications 9/1 | 2019-07-10 |
2017 |
Massimo Frittelli, Anotida Madzvamuse, Ivonne Sgura, Chandrasekhar Venkataraman Lumped finite elements for reaction–cross-diffusion systems on stationary surfaces published pages: 3008-3023, ISSN: 0898-1221, DOI: 10.1016/j.camwa.2017.07.044 |
Computers & Mathematics with Applications 74/12 | 2019-07-10 |
2018 |
Maria Alieva, Jacco van Rheenen, Marike L. D. Broekman Potential impact of invasive surgical procedures on primary tumor growth and metastasis published pages: 319-331, ISSN: 0262-0898, DOI: 10.1007/s10585-018-9896-8 |
Clinical & Experimental Metastasis 35/4 | 2019-07-10 |
2016 |
A. Madzvamuse, A. H. Chung Analysis and Simulations of Coupled Bulk-surface Reaction-Diffusion Systems on Exponentially Evolving Volumes published pages: 4-32, ISSN: 1760-6101, DOI: 10.1051/mmnp/201611502 |
Mathematical Modelling of Natural Phenomena 11/5 | 2019-07-10 |
2017 |
Maria Alieva, Andreia S. Margarido, Tamara Wieles, Erik R. Abels, Burcin Colak, Carla Boquetale, Herke Jan Noordmans, Tom J. Snijders, Marike L. Broekman, Jacco van Rheenen Preventing inflammation inhibits biopsy-mediated changes in tumor cell behavior published pages: 7529, ISSN: 2045-2322, DOI: 10.1038/s41598-017-07660-4 |
Scientific Reports 7/1 | 2019-07-10 |
2019 |
Dmytro Kotsur, Roman Yakobenchuk, Rudolf Leube, Reinhard Windoffer, Julian Mattes An algorithm for individual intermediate filament tracking published pages: , ISSN: , DOI: |
SAMBA: SIPAIM - MICCAI BIOMEDICAL WORKSHOP | 2019-07-10 |
2018 |
Eduard Campillo-Funollet, Chandrasekhar Venkataraman, Anotida Madzvamuse Bayesian Parameter Identification for Turing Systems on Stationary and Evolving Domains published pages: 1-24, ISSN: 0092-8240, DOI: 10.1007/s11538-018-0518-z |
Bulletin of Mathematical Biology | 2019-07-10 |
2018 |
Wakil Sarfaraz, Anotida Madzvamuse Domain-Dependent Stability Analysis of a Reaction–Diffusion Model on Compact Circular Geometries published pages: 1830024, ISSN: 0218-1274, DOI: 10.1142/s0218127418300240 |
International Journal of Bifurcation and Chaos 28/08 | 2019-07-10 |
2017 |
Wakil Sarfaraz, Anotida Madzvamuse Classification of parameter spaces for a reaction-diffusion model on stationary domains published pages: 33-51, ISSN: 0960-0779, DOI: 10.1016/j.chaos.2017.05.032 |
Chaos, Solitons & Fractals 103 | 2019-07-10 |
2017 |
Rudolf E. Leube, Marcin Moch, Reinhard Windoffer Intracellular Motility of Intermediate Filaments published pages: a021980, ISSN: 1943-0264, DOI: 10.1101/cshperspect.a021980 |
Cold Spring Harbor Perspectives in Biology 9/6 | 2019-07-10 |
2018 |
Anne PORA Impact of keratin network regulation on migrating cells published pages: , ISSN: , DOI: |
2019-07-10 | |
2015 |
Toshio Sekimura, Chandrasekhar Venkataraman, Anotida Madzvamuse A Model for Selection of Eyespots on Butterfly Wings published pages: e0141434, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0141434 |
PLOS ONE 10/11 | 2019-07-10 |
2018 |
Katerina Lomanov, Jesus Martinez del Rincon, Paul Miller, Hugh Gribben LAP-based tracking for focal adhesions published pages: , ISSN: , DOI: |
Irish Machine Vision and Image Processing Conference Proceedings 2018: Proceedings Yearly | 2019-07-10 |
2018 |
Arianna Fumagalli, Saskia J E Suijkerbuijk, Harry Begthel, Evelyne Beerling, Koen C Oost, Hugo J Snippert, Jacco van Rheenen, Jarno Drost A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression published pages: 235-247, ISSN: 1754-2189, DOI: 10.1038/nprot.2017.137 |
Nature Protocols 13/2 | 2019-07-10 |
2018 |
Massimo Frittelli, Anotida Madzvamuse, Ivonne Sgura, Chandrasekhar Venkataraman Numerical Preservation of Velocity Induced Invariant Regions for Reaction–Diffusion Systems on Evolving Surfaces published pages: 971-1000, ISSN: 0885-7474, DOI: 10.1007/s10915-018-0741-7 |
Journal of Scientific Computing 77/2 | 2019-07-10 |
2018 |
Laura Murphy, Chandrasekhar Venkataraman, Anotida Madzvamuse Parameter identification through mode isolation for reaction–diffusion systems on arbitrary geometries published pages: 1850053, ISSN: 1793-5245, DOI: 10.1142/s1793524518500535 |
International Journal of Biomathematics 11/04 | 2019-07-10 |
2018 |
Sander C Steenbeek, Thang V Pham, Joep de Ligt, Anoek Zomer, Jaco C Knol, Sander R Piersma, Tim Schelfhorst, Rick Huisjes, Raymond M Schiffelers, Edwin Cuppen, Connie R Jimenez, Jacco van Rheenen Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles published pages: e98357, ISSN: 0261-4189, DOI: 10.15252/embj.201798357 |
The EMBO Journal 37/15 | 2019-07-10 |
2018 |
Gloria Fabris, Alessandro Lucantonio, Nico Hampe, Erik Noetzel, Bernd Hoffmann, Antonio DeSimone, Rudolf Merkel Nanoscale Topography and Poroelastic Properties of Model Tissue Breast Gland Basement Membranes published pages: 1770-1782, ISSN: 0006-3495, DOI: 10.1016/j.bpj.2018.09.020 |
Biophysical Journal 115/9 | 2019-07-10 |
2018 |
Martin Rümmele CSI-Krebs: So findet man die passende Therapie published pages: 4-5, ISSN: , DOI: |
medianet Dossier - health economy 10/2018 | 2019-07-10 |
2018 |
Scott Rata, Maria F. Suarez Peredo Rodriguez, Stephy Joseph, Nisha Peter, Fabio Echegaray Iturra, Fengwei Yang, Anotida Madzvamuse, Jan G. Ruppert, Kumiko Samejima, Melpomeni Platani, Monica Alvarez-Fernandez, Marcos Malumbres, William C. Earnshaw, Bela Novak, Helfrid Hochegger Two Interlinked Bistable Switches Govern Mitotic Control in Mammalian Cells published pages: 3824-3832.e6, ISSN: 0960-9822, DOI: 10.1016/j.cub.2018.09.059 |
Current Biology 28/23 | 2019-07-10 |
2016 |
Anotida Madzvamuse, Hussaini Ndakwo, Raquel Barreira Stability analysis of reaction-diffusion models on evolving domains: The effects of cross-diffusion published pages: 2133-2170, ISSN: 1078-0947, DOI: 10.3934/dcds.2016.36.2133 |
Discrete and Continuous Dynamical Systems 36/4 | 2019-07-10 |
2016 |
Feng Wei Yang, Chandrasekhar Venkataraman, Vanessa Styles, Verena Kuttenberger, Elias Horn, Zeno von Guttenberg, Anotida Madzvamuse A computational framework for particle and whole cell tracking applied to a real biological dataset published pages: , ISSN: 0021-9290, DOI: 10.1016/j.jbiomech.2016.02.008 |
Journal of Biomechanics February 2016 | 2019-07-10 |
2016 |
Anotida Madzvamuse, Andy H.W. Chung The bulk-surface finite element method for reaction–diffusion systems on stationary volumes published pages: 9-21, ISSN: 0168-874X, DOI: 10.1016/j.finel.2015.09.002 |
Finite Elements in Analysis and Design 108 | 2019-07-10 |
2016 |
Anotida Madzvamuse, Sharon R. Lubkin A note on how to develop interdisciplinary collaborations between experimentalists and theoreticians published pages: 20160069, ISSN: 2042-8898, DOI: 10.1098/rsfs.2016.0069 |
Interface Focus 6/5 | 2019-07-10 |
2017 |
Melanie Graessl, Johannes Koch, Abram Calderon, Dominic Kamps, Soumya Banerjee, Tomáš Mazel, Nina Schulze, Jana Kathrin Jungkurth, Rutuja Patwardhan, Djamschid Solouk, Nico Hampe, Bernd Hoffmann, Leif Dehmelt, Perihan Nalbant An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns published pages: 4271-4285, ISSN: 0021-9525, DOI: 10.1083/jcb.201706052 |
The Journal of Cell Biology 216/12 | 2019-07-10 |
2016 |
Rodrigo Hernández Vera, Emil Schwan, Nikos Fatsis-Kavalopoulos, Johan Kreuger A Modular and Affordable Time-Lapse Imaging and Incubation System Based on 3D-Printed Parts, a Smartphone, and Off-The-Shelf Electronics published pages: e0167583, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0167583 |
PLOS ONE 11/12 | 2019-07-10 |
2016 |
A. Madzvamuse, A. H. Chung Analysis and Simulations of Coupled Bulk-surface Reaction-Diffusion Systems on Exponentially Evolving Volumes published pages: 4-32, ISSN: 1760-6101, DOI: 10.1051/mmnp/201611502 |
Mathematical Modelling of Natural Phenomena 11/5 | 2019-07-10 |
2016 |
Yang, F, Venkataraman, C, Styles, V and Madzvamuse, A A robust and efficient adaptive multigrid solver for the optimal control of phase field formulations of geometric evolution laws. published pages: 65-92, ISSN: 1815-2406, DOI: 10.4208/cicp.240715.080716a |
Communications in Computational Physics 2/17 | 2019-07-10 |
2016 |
Nicole Schwarz, Rudolf Leube Intermediate Filaments as Organizers of Cellular Space: How They Affect Mitochondrial Structure and Function published pages: 30, ISSN: 2073-4409, DOI: 10.3390/cells5030030 |
Cells 5/3 | 2019-07-10 |
2017 |
Saskia J.E. Suijkerbuijk, Jacco van Rheenen From good to bad: Intravital imaging of the hijack of physiological processes by cancer cells published pages: 328-337, ISSN: 0012-1606, DOI: 10.1016/j.ydbio.2017.04.015 |
Developmental Biology 428/2 | 2019-07-10 |
2018 |
D. Cusseddu, L. Edelstein-Keshet, J.A. Mackenzie, S. Portet, A. Madzvamuse A coupled bulk-surface model for cell polarisation published pages: , ISSN: 0022-5193, DOI: 10.1016/j.jtbi.2018.09.008 |
Journal of Theoretical Biology | 2019-07-10 |
2017 |
Kritika Sahni, Dmytro Kotsur, Georg Dreissen, Dr. Julian Mattes, Dr. Bernd Hoffmann,
Prof. Dr. Rudolf Merkel, Galiya Sakaeva MIGRATION COMPONENT DYNAMICS AND FRONT-REAR INTERPLAY published pages: , ISSN: , DOI: |
3rd International Symposium on Mechanobiology 2017 | 2019-07-10 |
2017 |
Galiya Sakaeva, Dmytro Kotsur, Kritika Sahni, Georg Dreissen, Julian Mattes, Bernd Hoffmann,
Rudolf Merkel POLARIZED EPITHELIAL CELL MIGRATION DEPENDS ON REAR END STRESS FIBER TENSION published pages: , ISSN: , DOI: |
3rd International Symposium on Mechanobiology 2017 | 2019-07-10 |
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