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MURAB SIGNED

MRI and Ultrasound Robotic Assisted Biopsy

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

MURAB project word cloud

Explore the words cloud of the MURAB project. It provides you a very rough idea of what is the project "MURAB" about.

murab components industrial expertise umcn breast place intends diagnostics ultrasound resonance disease workflow magnetic pushing medical cancer images right revolutionise elastography visible diseases imaging mri screening detection zgt kuka ambition probe technologies lesions treatment considering patients clinical deformation safe body robotics exact modalities muscle drastically techniques precision tissue save location cope robot procedure tissues muw combined slam clinically thanks researched paradigm technique create small siemens active validated innovation tas innovative match navigate lives market

Project "MURAB" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITEIT TWENTE Organization address address: DRIENERLOLAAN 5 city: ENSCHEDE postcode: 7522 NB website: www.utwente.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Netherlands [NL]
Project website	http://www.murabproject.eu
Total cost	4˙343˙307 €
EC max contribution	3˙982˙307 € (92%)
Programme	1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
Code Call	H2020-ICT-2015
Funding Scheme	RIA
Starting year	2016
Duration (year-month-day)	from 2016-01-01 to 2020-06-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITEIT TWENTE UNIVERSITEIT TWENTE Organization address address: DRIENERLOLAAN 5 city: ENSCHEDE postcode: 7522 NB website: www.utwente.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ENSCHEDE)	coordinator	1˙210˙800.00
2	KUKA DEUTSCHLAND GMBH KUKA DEUTSCHLAND GMBH Organization address address: ZUGSPITZSTRASSE 140 city: AUGSBURG postcode: 86165 website: www.kuka-robotics.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (AUGSBURG)	participant	1˙250˙000.00
3	STICHTING KATHOLIEKE UNIVERSITEIT STICHTING KATHOLIEKE UNIVERSITEIT Organization address address: GEERT GROOTEPLEIN NOORD 9 city: NIJMEGEN postcode: 6525 EZ website: www.radboudumc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (NIJMEGEN)	participant	741˙207.00
4	UNIVERSITA DEGLI STUDI DI VERONA UNIVERSITA DEGLI STUDI DI VERONA Organization address address: VIA DELL ARTIGLIERE 8 city: VERONA postcode: 37129 website: www.univr.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (VERONA)	participant	491˙875.00
5	STICHTING ZIEKENHUISGROEP TWENTE STICHTING ZIEKENHUISGROEP TWENTE Organization address address: ZILVERMEEUW 1 city: ALMELO postcode: 7609 PP website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ALMELO)	participant	149˙000.00
6	MEDIZINISCHE UNIVERSITAET WIEN MEDIZINISCHE UNIVERSITAET WIEN Organization address address: SPITALGASSE 23 city: WIEN postcode: 1090 website: www.meduniwien.ac.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (WIEN)	participant	139˙425.00
7	SIEMENS NEDERLAND NV SIEMENS NEDERLAND NV Organization address address: PRINSES BEATRIXLAAN 800 city: 'S-GRAVENHAGE postcode: 2595BN website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL ('S-GRAVENHAGE)	participant	0.00

Map

Project objective

The MURAB project has the ambition to revolutionise the way cancer screening and muscle diseases are researched for patients and has the potential to save lives by early detection and treatment. The project intends to create a new paradigm in which, the precision of great medical imaging modalities like MRI and Ultrasound are combined with the precision of robotics in order to target the right place in the body. This will be achieved by identifying a target using Magnetic Resonance Imaging (MRI) and then use a robot with an ultrasound (US) probe to match the images and navigate to the right location. This will be done thanks to a new innovative technique, which will be developed in the project and called Tissue Active Slam (TAS) which will use different techniques and modalities, like elastography, in order to cope with the deformation of the tissues. Such a procedure has the potential to drastically improve the clinical workflow and save lives by ensuring an exact targeting of (small) lesions, which are visible under MRI and not under US. Technologies developed within MURAB also have the potential to improve other clinical procedures. Clinically, two applications will be targeted and validated in the project: breast cancer diagnostics (MUW and ZGT) and muscle disease diagnostics (UMCN). Considering the potential for the market, industrial partners are involved with expertise in the delivery of safe robotics components and applications (KUKA), as well as with great knowledge and ambition in pushing innovation to the medical market (SIEMENS).

Deliverables

List of deliverables.
Final Design Robotic Head	Demonstrators, pilots, prototypes	2020-04-07 20:42:07
Professional Video on the MURAB Concept	Websites, patent fillings, videos etc.	2020-04-07 20:42:07
Progress report on US/MR image registration	Documents, reports	2020-04-07 20:42:07
Review on local feature extraction in 3D medical images	Documents, reports	2020-04-07 20:42:07
Data Management Plan	Documents, reports	2020-04-07 20:42:07
Establishment of the Advisory Board	Other	2020-04-07 20:42:07
MURAB Web Page	Websites, patent fillings, videos etc.	2020-04-07 20:42:07
Robot flange	Demonstrators, pilots, prototypes	2020-04-07 20:42:07
Consideration and recommendation on preclinical tests	Documents, reports	2020-04-07 20:42:07
Finalization of the system architecture	Documents, reports	2020-04-07 20:42:07
Review on non-rigid local deformation models in 3D medical images.	Documents, reports	2020-04-07 20:42:07
Review on state estimators applicable for SLAM-like problems.	Documents, reports	2020-04-07 20:42:07
ORDP: Data Management Plan	Open Research Data Pilot	2020-04-07 20:42:07
Review on state space models that describe inertial behaviour.	Documents, reports	2020-04-07 20:42:07

Take a look to the deliverables list in detail: detailed list of MURAB deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2017	A.S.S. Meel-van den Abeelen, G. Weijers, J.C.M. van Zelst, J.M. Thijssen, R.M. Mann, C.L. de Korte 3D quantitative breast ultrasound analysis for differentiating fibroadenomas and carcinomas smaller than 1 cm published pages: 141-147, ISSN: 0720-048X, DOI: 10.1016/j.ejrad.2017.01.006	European Journal of Radiology 88	2020-04-07
2016	D. Dall\'Alba, F. Bovo, D. Zerbato, A. Forgione, P. Fiorini Towards an intra-operative calibration-preserving freehand ultrasound system published pages: , ISSN: , DOI:	Computer Aided Radiology and Surgery	2020-04-07
2017	Bogdan M. Maris, FranÃ§oise J. Siepel, Diego Dallâ€™Alba, Vincent Groenhuis, Paolo Fiorini, Stefano Stramigioli MURAB: MRI and ultrasound robotic assisted biopsy published pages: , ISSN: , DOI:		2020-04-07
2018	Johannes Lachner Combining MRI and Ultrasound for robotic assisted biopsy in breast cancer and muscle diseases published pages: , ISSN: , DOI:	22/02/18	2020-04-07
2018	Allmendinger, Felix Program the Task, not the Robot! published pages: , ISSN: , DOI:	02/09/18	2020-04-07
2017	Allmendinger, Felix Operational Space Control from an Industrial Point of View published pages: , ISSN: , DOI:	23/10/17	2020-04-07
2019	Anton Nikolaev, Hendrik H. G. Hansen, Eleonora Tagliabue, Bogdan Mihai Maris, Vincent Groenhuis, Chris L. de Korte Ultrasound-guided breast biopsy of ultrasound occult lesions using multimodality image co-registration and tissue displacement tracking published pages: Poster, ISSN: , DOI:		2020-04-07
2019	Bogdan Maris, Eros Ghignoni, Paolo Fiorini Convolutional network for multi-planar pose prediction in medical imaging published pages: , ISSN: , DOI:		2020-04-07
2018	Francesco Visentin, Vincent Groenhuis, Bogdan Maris, Diego Dallâ€™Alba, FranÃ§oise Siepel, Stefano Stramigioli, Paolo Fiorini Iterative simulations to estimate the elastic properties from a series of MRI images followed by MRI-US validation published pages: , ISSN: 0140-0118, DOI: 10.1007/s11517-018-1931-z	Medical & Biological Engineering & Computing	2020-04-07
2018	Eleonora Tagliabue, Bogdan Maris, Andrea Roberti, Anton nikolaev, Leon De Jong, Paolo Fiorini Patient specific FE modeling for deformable breast registration published pages: , ISSN: , DOI:		2020-04-07
2019	Lachner J, Schettino V, Allmendinger F, Fiore MD, Ficuciello F, Siciliano B, Stramigioli S The influence of coordinates in robotic manipulability analysis published pages: , ISSN: , DOI:	IEEE Robotics and Automation Letters (RA-L)	2020-04-07
2018	L. de Jong1, M. K. Welleweerd2, J. van Zelst1, F. J. Siepel2, S. Stramigioli2, J. J. Futterer1, R. M. Mann1, C. L. de Korte1; 1Nijmegen/NL, 2Enschede/NL Breast lesion markers for 3D ultrasound examinations of the breast published pages: , ISSN: , DOI: 10.1594/ecr2018/c-2956	01/03/2018	2020-04-07
2019	Leon de Jong, Anton Nikolaev, Anna Greco, Jurgen FÃ¼tterer, Chris de Korte Automated 3D Ultrasound for Quantitative Assessment of Mechanical Properties of Skeletal Muscle published pages: Poster 20, ISSN: , DOI:	24/01/2019	2020-04-07
2017	Bogdan M. Maris, FranÃ§oise J. Siepel, Diego Dallâ€™Alba, Vincent Groenhuis, Paolo Fiorini, Stefano Stramigioli MURAB: A new robotic system for high precision biopsy published pages: , ISSN: , DOI:	September 24â€“28, 2017	2020-04-07
2018	Johannes Lachner Safety related task level control with redundant manipulator in medical application published pages: , ISSN: , DOI:	CURAC PhD workshop 24/05/18	2020-04-07
2018	Vincent Groenhuis, Francesco Visentin, FranÃ§oise J. Siepel, Bogdan M. Maris, Diego Dallâ€™alba, Paolo Fiorini, Stefano Stramigioli Analytical derivation of elasticity in breast phantoms for deformation tracking published pages: 1641-1650, ISSN: 1861-6410, DOI: 10.1007/s11548-018-1803-x	International Journal of Computer Assisted Radiology and Surgery 13/10	2020-04-07
2017	Francesco Visentin, Bogdan Maris, Paolo Fiorini Breast Tissue Parameter Estimation Using Finite Element Analysis published pages: , ISSN: , DOI:		2020-04-07
2019	Eleonora Tagliabue, Diego Dallâ€™Alba, Enrico Magnabosco, Chiara Tenga, Paolo Fiorini A position-based framework for the prediction of probe-induced lesion displacement in Ultrasound-guided breast biopsy published pages: , ISSN: , DOI:		2020-04-07

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