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FBI SIGNED

Multimodal, Functional Bio-Photonic Imaging

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

FBI project word cloud

Explore the words cloud of the FBI project. It provides you a very rough idea of what is the project "FBI" about.

restricted world biomedical 15 modalities techniques fbi capture free combining biomarker outcomes interdisciplinary onset biological solutions components limited lesions spectroscopy staging intrinsic forming standalone network integration respectively fosters microangiography endoscopy detection photonic coherence efficient commercial clinical sciences barriers proposes trained said therapy treatment esrs contrast grading multimodal industry laser biochemical mechanisms rates issue educating lack huge scanning earlier feasible sources suspicious unmet combine diagnosis analysed tomography education relations translation label depending accordingly endoscopes optical translating raman companies invasive significantly shown photon platform simultaneously clinics morphological recurrence imaging time disease optoacoustic academic

Project "FBI" data sheet

The following table provides information about the project.

Coordinator	DANMARKS TEKNISKE UNIVERSITET Organization address address: ANKER ENGELUNDSVEJ 1 BYGNING 101 A city: KGS LYNGBY postcode: 2800 website: www.dtu.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Denmark [DK]
Project website	https://fbi-itn.eu/
Total cost	3˙902˙716 €
EC max contribution	3˙902˙716 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2016
Funding Scheme	MSCA-ITN-ETN
Starting year	2016
Duration (year-month-day)	from 2016-10-01 to 2020-09-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	DANMARKS TEKNISKE UNIVERSITET DANMARKS TEKNISKE UNIVERSITET Organization address address: ANKER ENGELUNDSVEJ 1 BYGNING 101 A city: KGS LYNGBY postcode: 2800 website: www.dtu.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (KGS LYNGBY)	coordinator	580˙163.00
2	MEDIZINISCHE UNIVERSITAET WIEN MEDIZINISCHE UNIVERSITAET WIEN Organization address address: SPITALGASSE 23 city: WIEN postcode: 1090 website: www.meduniwien.ac.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (WIEN)	participant	767˙802.00
3	ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE Organization address address: BATIMENT CE 3316 STATION 1 city: LAUSANNE postcode: 1015 website: www.epfl.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (LAUSANNE)	participant	530˙453.00
4	TECHNISCHE UNIVERSITEIT EINDHOVEN TECHNISCHE UNIVERSITEIT EINDHOVEN Organization address address: GROENE LOPER 3 city: EINDHOVEN postcode: 5612 AE website: www.tue.nl/en contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (EINDHOVEN)	participant	510˙748.00
5	TECHNISCHE UNIVERSITAET MUENCHEN TECHNISCHE UNIVERSITAET MUENCHEN Organization address address: Arcisstrasse 21 city: MUENCHEN postcode: 80333 website: www.tu-muenchen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUENCHEN)	participant	498˙432.00
6	NKT PHOTONICS A/S NKT PHOTONICS A/S Organization address address: BLOKKEN 84 city: BIRKEROD postcode: 3460 website: www.nktphotonics.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (BIRKEROD)	participant	290˙081.00
7	PHILIPS ELECTRONICS NEDERLAND BV PHILIPS ELECTRONICS NEDERLAND BV Organization address address: HIGH TECH CAMPUS 52 city: EINDHOVEN postcode: 5656 AG website: www.philips.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (EINDHOVEN)	participant	255˙374.00
8	ITHERA MEDICAL GMBH ITHERA MEDICAL GMBH Organization address address: ZIELSTATTSTRASSE 13 city: MUNCHEN postcode: 81379 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUNCHEN)	participant	249˙216.00
9	EKSPLA UAB EKSPLA UAB Organization address address: SAVANORIU PR 231 city: VILNIUS postcode: 2300 website: www.ekspla.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	LT (VILNIUS)	participant	220˙442.00
10	FEMTOLASERS PRODUKTIONS GMBH FEMTOLASERS PRODUKTIONS GMBH Organization address address: Kleinengerdorferstrasse 24 city: KORNEUBURG postcode: 2100 website: www.femtolasers.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (KORNEUBURG)	participant	0.00
11	ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM Organization address address: MEIBERGDREEF 15 city: AMSTERDAM postcode: 1105AZ website: www.amc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	partner	0.00
12	ALBERT-LUDWIGS-UNIVERSITAET FREIBURG ALBERT-LUDWIGS-UNIVERSITAET FREIBURG Organization address address: FAHNENBERGPLATZ city: FREIBURG postcode: 79098 website: www.uni-freiburg.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (FREIBURG)	partner	0.00
13	CARL ZEISS AG CARL ZEISS AG Organization address address: CARL ZEISS STRASSE 22 city: OBERKOCHEN postcode: 73447 website: www.zeiss.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (OBERKOCHEN)	partner	0.00
14	IMASONIC SAS IMASONIC SAS Organization address address: ZA RUE DES SAVOUROTS city: VORAY SUR L'OGNON postcode: 70190 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (VORAY SUR L'OGNON)	partner	0.00
15	SMART PHOTONICS BV SMART PHOTONICS BV Organization address address: HIGH TECH CAMPUS 29 city: EINDHOVEN postcode: 5656 AE website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (EINDHOVEN)	partner	0.00

Map

Project objective

FBI fosters education of ESRs on an emerging, multimodal imaging platform and its translation into clinical and biological applications. In FBI, 15 ESRs are trained at world-leading European academic institutions and companies, thus forming strong interdisciplinary relations between industry, technical sciences and clinical end-users.

Optical imaging has huge potential to address unmet clinical needs by combining non-invasive and real-time capture of biomedical information; thus enabling earlier onset of treatment, reduced therapy costs, reduced recurrence rates, and improved clinical outcomes. Up to now, optical modalities were applied as standalone techniques each targeting one biomarker. Recently it has been shown that diagnosis is significantly improved by combining different contrast mechanisms simultaneously in a multimodal approach, i.e., staging and grading of lesions is feasible.

FBI proposes to combine a selection of modalities depending on the targeted disease. Suspicious lesions are analysed with optical coherence tomography, optoacoustic tomography, multi-photon tomography, and Raman spectroscopy to provide morphological, label-free microangiography, and intrinsic biochemical information, respectively. An important issue is the need for endoscopy: combining said modalities into endoscopes is challenging due to the integration of different imaging concepts, scanning and detection methods, and laser sources. Accordingly, there is a huge need for effectively translating these technical solutions to industry and clinics, which traditionally is restricted by lack of understanding of applications or limited knowledge of new technology.

All these barriers are addressed by FBI through research and development of novel photonic components and systems, through educating ESRs in understanding clinical, biological and commercial challenges, and through developing tailored technical solutions and efficient translation of technology within a strong network.

Deliverables

List of deliverables.
Websites (external and internal for data sharing)	Websites, patent fillings, videos etc.	2020-04-08 10:01:22
Mid Term report	Documents, reports	2020-04-08 10:01:22
Tissue classification technology based on OCT and its combination with US	Documents, reports	2020-04-08 10:01:22
Compact broadband Ti:sapphire laser technology incorporating new pump sources	Documents, reports	2020-04-08 10:01:22
Progress Report	Documents, reports	2020-04-08 10:01:22

Take a look to the deliverables list in detail: detailed list of FBI deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2020	Mikael T. ErkkilÃ¤, David Reichert, Nancy Hecker-Denschlag, Marco Wilzbach, Christoph Hauger, Rainer A. Leitgeb, Johanna Gesperger, Barbara Kiesel, Thomas Roetzer, Georg Widhalm, Wolfgang Drexler, Angelika Unterhuber, Marco Andreana Surgical microscope with integrated fluorescence lifetime imaging for 5-aminolevulinic acid fluorescence-guided neurosurgery published pages: 1, ISSN: 1083-3668, DOI: 10.1117/1.jbo.25.7.071202	Journal of Biomedical Optics 25/07	2020-04-08
2020	David Reichert, Mikael T. ErkkilÃ¤, Gerhard Holst, Nancy Hecker-Denschlag, Marco Wilzbach, Christoph Hauger, Wolfgang Drexler, Johanna Gesperger, Barbara Kiesel, Thomas Roetzer, Angelika Unterhuber, Georg Widhalm, Rainer A. Leitgeb, Marco Andreana Towards real-time wide-field fluorescence lifetime imaging of 5-ALA labeled brain tumors with multi-tap CMOS cameras published pages: 1598, ISSN: 2156-7085, DOI: 10.1364/boe.382817	Biomedical Optics Express 11/3	2020-04-08
2020	Fabian Placzek, Eliana Cordero Bautista, Simon Kretschmer, Lara M. Wurster, Florian Knorr, Gerardo GonzÃ¡lez-Cerdas, Mikael T. ErkkilÃ¤, Patrick Stein, Ã‡aÄŸlar Ataman, Gregers G. Hermann, Karin Mogensen, Thomas Hasselager, Peter E. Andersen, Hans Zappe, JÃ¼rgen Popp, Wolfgang Drexler, Rainer A. Leitgeb, Iwan W. Schie Morpho-molecular ex vivo detection and grading of non-muscle-invasive bladder cancer using forward imaging probe based multimodal optical coherence tomography and Raman spectroscopy published pages: , ISSN: 0003-2654, DOI: 10.1039/c9an01911a	The Analyst	2020-04-08
2017	Rastko PajkoviÄ‡, Kevin Williams, Erwin Bente Tuning of an integrated tunable laser for swept source optical coherence tomography Tuning of an Integrated Tunable Laser for Swept Source Optical Coherence Tomography published pages: 164-167, ISSN: , DOI:	Tuning of an integrated tunable laser for swept source optical coherence tomography	2020-04-08
2019	Hailong He, Antonios Stylogiannis, Parastoo Afshari, Tobias Wiedemann, Katja Steiger, Andreas Buehler, Christian Zakian, Vasilis Ntziachristos Capsule optoacoustic endoscopy for esophageal imaging published pages: , ISSN: 1864-063X, DOI: 10.1002/jbio.201800439	Journal of Biophotonics 12/10	2020-04-08
2020	Pierre-Marc Dansette, Raimundas Burokas, Laurynas Veselis, Audrius ZaukeviÄius, Andrejus Michailovas, Nerijus Rusteika Peculiarities of second harmonic generation with chirped femtosecond pulses at high conversion efficiency published pages: 124462, ISSN: 0030-4018, DOI: 10.1016/j.optcom.2019.124462	Optics Communications 455	2020-04-08
2019	R. A. Leitgeb En face optical coherence tomography: a technology review [Invited] published pages: 2177, ISSN: 2156-7085, DOI: 10.1364/BOE.10.002177	Biomedical Optics Express 10/5	2020-04-08
2019	Daniela Bovenkamp, Alexander Micko, Jeremias PÃ¼ls, Fabian Placzek, Romana HÃ¶ftberger, Greisa Vila, Rainer Leitgeb, Wolfgang Drexler, Marco Andreana, Stefan Wolfsberger, Angelika Unterhuber Line Scan Raman Microspectroscopy for Label-Free Diagnosis of Human Pituitary Biopsies published pages: 3577, ISSN: 1420-3049, DOI: 10.3390/molecules24193577	Molecules 24/19	2020-04-08
2019	Roger FonollÃ , Thom Scheeve, Maarten R. Struyvenberg, Wouter L. Curvers, Albert J. de Groof, Fons van der Sommen, Erik J. Schoon, Jacques J.G.H.M. Bergman, Peter H.N. de With Ensemble of Deep Convolutional Neural Networks for Classification of Early Barrettâ€™s Neoplasia Using Volumetric Laser Endomicroscopy published pages: 2183, ISSN: 2076-3417, DOI: 10.3390/app9112183	Applied Sciences 9/11	2020-04-08
2016	Lars Kirsten, Simon BaumgÃ¤rtner, Mikael Timo ErkkilÃ¤, Jonas Golde, Max Kemper, Thomas Stoppe, Matthias Bornitz, Marcus Neudert, Thomas Zahnert, Edmund Koch Doppler optical coherence tomography as a promising tool for detecting fluid in the human middle ear published pages: , ISSN: 2364-5504, DOI: 10.1515/cdbme-2016-0098	Current Directions in Biomedical Engineering 2/1	2020-04-08
2017	Lars Kirsten, Joseph Morgenstern, Mikael Timo ErkkilÃ¤, Martin Schindler, Jonas Golde, Julia Walther, Max Kemper, Thomas Stoppe, Matthias Bornitz, Marcus Neudert, Thomas Zahnert, Edmund Koch Functional and morphological imaging of the human tympanic membrane with endoscopic optical coherence tomography published pages: , ISSN: 2364-5504, DOI: 10.1515/cdbme-2017-0021	Current Directions in Biomedical Engineering 3/2	2020-04-08
2019	R. A. Leitgeb En face optical coherence tomography: a technology review [Invited] published pages: 2177, ISSN: 2156-7085, DOI: 10.1364/boe.10.002177	Biomedical Optics Express 10/5	2020-04-08
2019	Lars Kirsten, Martin Schindler, Joseph Morgenstern, Mikael Timo ErkkilÃ¤, Jonas Golde, Julia Walther, Pascal Rottmann, Max Kemper, Matthias Bornitz, Marcus Neudert, Thomas Zahnert, Edmund Koch Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane published pages: 1, ISSN: 1083-3668, DOI: 10.1117/1.JBO.24.3.031017	Journal of Biomedical Optics 24/03	2020-04-08
2018	Daniela Bovenkamp, Ryan Sentosa, Elisabet Rank, Mikael ErkkilÃ¤, Fabian Placzek, Jeremias PÃ¼ls, Wolfgang Drexler, Rainer Leitgeb, Nathalie Garstka, Shahrokh Shariat, Clara Stiebing, Iwan Schie, JÃ¼rgen Popp, Marco Andreana, Angelika Unterhuber Combination of High-Resolution Optical Coherence Tomography and Raman Spectroscopy for Improved Staging and Grading in Bladder Cancer published pages: 2371, ISSN: 2076-3417, DOI: 10.3390/app8122371	Applied Sciences 8/12	2020-04-08
2018	Roger Fonolla Navarro, Fons Van Der Sommen, Peter H N De With, Ramon M Schreuder, Erik J Schoon Polyp malignancy classification with CNN features based on Blue Laser and Linked Color Imaging published pages: , ISSN: , DOI:	Proceedings of NCCV2018	2020-04-08
2018	Martin Schindler, Lars Kirsten, Joseph Morgenstern, Jonas Golde, Mikael ErkkilÃ¤, Julia Walther, Max Kemper, Matthias Bornitz, Marcus Neudert, Thomas Zahnert, Edmund Koch Imaging of the human tympanic membrane by endoscopic optical coherence tomography published pages: 305-308, ISSN: 2364-5504, DOI: 10.1515/cdbme-2018-0074	Current Directions in Biomedical Engineering 4/1	2020-04-08
2018	Orly B. Tarun, Maksim Yu Eremchev, Sylvie Roke Interaction of Oil and Lipids in Freestanding Lipid Bilayer Membranes Studied with Label-Free High-Throughput Wide-Field Second-Harmonic Microscopy published pages: 11305-11310, ISSN: 0743-7463, DOI: 10.1021/acs.langmuir.8b01790	Langmuir 34/38	2020-04-08
2019	Lara M. Wurster, Ronak N. Shah, Fabian Placzek, Simon Kretschmer, Michael Niederleithner, Laurin Ginner, Jason Ensher, Michael P. Minneman, Erich E. Hoover, Hans Zappe, Wolfgang Drexler, Rainer A. Leitgeb, Ã‡aÄŸlar Ataman Endoscopic optical coherence tomography angiography using a forward imaging piezo scanner probe published pages: e201800382, ISSN: 1864-063X, DOI: 10.1002/jbio.201800382	Journal of Biophotonics 2019-01-16	2020-04-08
2019	Mikael T. ErkkilÃ¤, Bianca Bauer, Nancy Hecker-Denschlag, Maria J. Madera Medina, Rainer A. Leitgeb, Angelika Unterhuber, Johanna Gesperger, Thomas Roetzer, Christoph Hauger, Wolfgang Drexler, Georg Widhalm, Marco Andreana Widefield fluorescence lifetime imaging of protoporphyrin IX for fluorescence-guided neurosurgery: an ex vivo feasibility study published pages: , ISSN: 1864-063X, DOI: 10.1002/jbio.201800378	Journal of Biophotonics	2020-04-08
2019	P. Albrodt, M. T. Jamal, A. K. Hansen, O. B. Jensen, G. Blume, K. Paschke, P. Crump, P. Georges, G. Lucas-Leclin Coherent combining of high brightness tapered amplifiers for efficient non-linear conversion published pages: 928, ISSN: 1094-4087, DOI: 10.1364/oe.27.000928	Optics Express 27/2	2020-04-08
2017	Carlos Macias-Romero, Igor Nahalka, Halil I. Okur, Sylvie Roke Optical imaging of surface chemistry and dynamics in confinement published pages: 784-788, ISSN: 0036-8075, DOI: 10.1126/science.aal4346	Science 357/6353	2020-04-08

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