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VIRUSCAN SIGNED

Optomechanics for Virology

Total Cost €

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EC-Contrib. €

0

Partnership

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 VIRUSCAN project word cloud

Explore the words cloud of the VIRUSCAN project. It provides you a very rough idea of what is the project "VIRUSCAN" about.

lately    latent    identification    quick    interdisciplinary    africa    west    pathogens    overcome    rapid    protocols    nanoelectromechanics    infective    full    transfusions    infectious    viruses    technologies    nanoscale    infections    applicability    quantum    ebola    physical    mass    biophysics    safety    viruscan    ground    biosensing    gravitational    nucleic    adsorbates    clinical    acid    discern    parallel    viral    act    stages    mechanical    consuming    trustworthy    situations    delivered    nanoelectromechanical    stiffness    detection    spread    time    reducing    constraints    diagnostic    asses    diagnosis    patients    gold    regulator    ones    blood    treatment    demonstrated    zika    served    personalized    life    spectrometry    adjustments    cheaper    physics    emergency    demands    levels    virus    fundamental    infectivity    optomechanics    create    frontier    intrinsic    screening    standard    native    cycle    wave    disentangled    advancements    particles    tackle    community    mutations    pathogen    characterization    antibiotics    brazil    platform   

Project "VIRUSCAN" data sheet

The following table provides information about the project.

Coordinator
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS 

Organization address
address: CALLE SERRANO 117
city: MADRID
postcode: 28006
website: http://www.csic.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website https://viruscanproject.eu/
 Total cost 7˙148˙586 €
 EC max contribution 7˙148˙586 € (100%)
 Programme 1. H2020-EU.1.2.2. (FET Proactive)
 Code Call FETPROACT-2016
 Funding Scheme RIA
 Starting year 2016
 Duration (year-month-day) from 2016-11-01   to  2021-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) coordinator 1˙248˙082.00
2    COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES FR (PARIS 15) participant 1˙098˙870.00
3    NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO NL (DEN HAAG) participant 1˙079˙262.00
4    HEINRICH-PETTE INSTITUT LEIBNIZ INSTITUT FUER EXPERIMENTELLE VIROLOGIE DE (HAMBURG) participant 882˙500.00
5    UNIVERSITE DE PARIS FR (PARIS) participant 856˙486.00
6    FASMATECH EPISTIMONIKI KAI TECHNOLOGIKI ANONYMI ETAIREIA EL (AFIDNES ATTIKIS) participant 800˙572.00
7    SERVICIO MADRILENO DE SALUD ES (MADRID) participant 603˙750.00
8    RIJKSUNIVERSITEIT GRONINGEN NL (GRONINGEN) participant 579˙062.00
9    UNIVERSITE PARIS DIDEROT - PARIS 7 FR (PARIS) participant 0.00

Map

 Project objective

Viral infections diagnosis demands novel, cheaper and rapid technologies to overcome present constraints. Current gold standard for diagnosis of viral infections is based on pathogen-targeted nucleic acid identification; thus, it cannot discern infectious stages from latent ones and it demands time consuming adjustments when mutations occur or new emerging viruses are to be included in the diagnostic protocols. Lately, optomechanics has served to fundamental advancements in physics, from gravitational wave detection to the study of mechanical quantum ground states but it has not yet delivered its full applicability potential. VIRUSCAN aims to apply frontier advancements in optomechanics to the biosensing and diagnostic fields and to create a new interdisciplinary research community with the goal to advance optomechanics, nanoelectromechanics, native mass spectrometry and biophysics towards clinical applications. VIRUSCAN will provide a novel technology capable to identify viral particles and asses their infective potential through the characterization of two physical parameters: mass and stiffness. Stiffness of viral particles has been recently known to act as a regulator of their infectivity at different stages of the virus life cycle. In parallel, advancements in nanoelectromechanical systems have recently demonstrated that stiffness and mass information from nanoscale adsorbates can be disentangled. Targeting intrinsic physical properties of viral particles will allow developing an open platform that will tackle any virus and their mutations. VIRUSCAN will have impact at all levels by: providing a personalized treatment to the patients, reducing the use of not effective antibiotics, increasing safety in blood transfusions, allowing a quick and trustworthy response to emergency situations (e.g. recent EBOLA in West Africa and the ZIKA in Brazil), reducing the spread of viral infections, reducing costs per analysis and screening of a wide range of pathogens.

 Publications

year authors and title journal last update
List of publications.
2017 Valerio Pini, Daniel Ramos, Carmen M. Dominguez, Jose Jaime Ruz, Oscar Malvar, Priscila M. Kosaka, Zachary J. Davis, Javier Tamayo, Montserrat Calleja
Optimization of the readout of microdrum optomechanical resonators
published pages: 37-41, ISSN: 0167-9317, DOI: 10.1016/j.mee.2017.10.008
Microelectronic Engineering 183-184 2020-02-19
2018 Ronja Pogan, Carola Schneider, Rudolph Reimer, Grant Hansman, Charlotte Uetrecht
Norovirus-like VP1 particles exhibit isolate dependent stability profiles
published pages: 64006, ISSN: 0953-8984, DOI: 10.1088/1361-648x/aaa43b
Journal of Physics: Condensed Matter 30/6 2020-02-19
2017 Carmen M. Domínguez, Daniel Ramos, Jesús Mingorance, José L. G. Fierro, Javier Tamayo, Montserrat Calleja
Direct Detection of OXA-48 Carbapenemase Gene in Lysate Samples through Changes in Mechanical Properties of DNA Monolayers upon Hybridization
published pages: 968-973, ISSN: 0003-2700, DOI: 10.1021/acs.analchem.7b04094
Analytical Chemistry 90/1 2020-02-19
2018 J. J. Ruz, V. Pini, O. Malvar, P. M. Kosaka, M. Calleja, J. Tamayo
Effect of surface stress induced curvature on the eigenfrequencies of microcantilever plates
published pages: 105213, ISSN: 2158-3226, DOI: 10.1063/1.5053561
AIP Advances 8/10 2020-02-19
2018 Eloise Pariset, Charlotte Parent, Yves Fouillet, Boizot François, Nicolas Verplanck, Frédéric Revol-Cavalier, Aurélie Thuaire, Vincent Agache
Separation of Biological Particles in a Modular Platform of Cascaded Deterministic Lateral Displacement Modules
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-34958-8
Scientific Reports 8/1 2020-02-19
2018 Joanna Luczkowiak, Fatima Lasala, Marta Mora-Rillo, Jose R Arribas, Rafael Delgado
Broad Neutralizing Activity Against Ebolaviruses Lacking the Mucin-Like Domain in Convalescent Plasma Specimens From Patients With Ebola Virus Disease
published pages: S574-S581, ISSN: 0022-1899, DOI: 10.1093/infdis/jiy302
The Journal of Infectious Diseases 218/suppl_5 2020-02-19
2018 Eloise Pariset, Catherine Pudda, François Boizot, Nicolas Verplanck, Frédéric Revol-Cavalier, Jean Berthier, Aurélie Thuaire, Vincent Agache
Purification of complex samples: Implementation of a modular and reconfigurable droplet-based microfluidic platform with cascaded deterministic lateral displacement separation modules
published pages: e0197629, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0197629
PLOS ONE 13/5 2020-02-19
2018 Ronja Pogan, Jasmin Dülfer, Charlotte Uetrecht
Norovirus assembly and stability
published pages: 59-65, ISSN: 1879-6257, DOI: 10.1016/j.coviro.2018.05.003
Current Opinion in Virology 31 2020-02-19
2017 Priscila M. Kosaka, Montserrat Calleja, Javier Tamayo
Optomechanical devices for deep plasma cancer proteomics
published pages: , ISSN: 1044-579X, DOI: 10.1016/j.semcancer.2017.08.011
Seminars in Cancer Biology 2020-02-19

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