AgeConsolidate SIGNED
The Missing Link of Episodic Memory Decline in Aging: The Role of Inefficient Systems Consolidation
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0AgeConsolidate project word cloud
Explore the words cloud of the AgeConsolidate project. It provides you a very rough idea of what is the project "AgeConsolidate" about.
Project "AgeConsolidate" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSITETET I OSLO
Organization address contact info |
| Coordinator Country | Norway [NO] |
| Total cost | 1˙999˙481 € |
| EC max contribution | 1˙999˙481 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2016-COG |
| Funding Scheme | ERC-COG |
| Starting year | 2017 |
| Duration (year-month-day) | from 2017-05-01 to 2022-04-30 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSITETET I OSLO | NO (OSLO) | coordinator | 1˙999˙481.00 |
Map
Project objective
Which brain mechanisms are responsible for the faith of the memories we make with age, whether they wither or stay, and in what form? Episodic memory function does decline with age. While this decline can have multiple causes, research has focused almost entirely on encoding and retrieval processes, largely ignoring a third critical process– consolidation. The objective of AgeConsolidate is to provide this missing link, by combining novel experimental cognitive paradigms with neuroimaging in a longitudinal large-scale attempt to directly test how age-related changes in consolidation processes in the brain impact episodic memory decline. The ambitious aims of the present proposal are two-fold: (1) Use recent advances in memory consolidation theory to achieve an elaborate model of episodic memory deficits in aging (2) Use aging as a model to uncover how structural and functional brain changes affect episodic memory consolidation in general The novelty of the project lies in the synthesis of recent methodological advances and theoretical models for episodic memory consolidation to explain age-related decline, by employing a unique combination of a range of different techniques and approaches. This is ground-breaking, in that it aims at taking our understanding of the brain processes underlying episodic memory decline in aging to a new level, while at the same time advancing our theoretical understanding of how episodic memories are consolidated in the human brain. To obtain this outcome, I will test the main hypothesis of the project: Brain processes of episodic memory consolidation are less effective in older adults, and this can account for a significant portion of the episodic memory decline in aging. This will be answered by six secondary hypotheses, with 1-3 experiments or tasks designated to address each hypothesis, focusing on functional and structural MRI, positron emission tomography data and sleep experiments to target consolidation from different angles.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2018 |
Inge K. Amlien, Markus H. Sneve, Didac Vidal-Piñeiro, Kristine B. Walhovd, Anders M. Fjell The Lifespan Trajectory of the Encoding-Retrieval Flip: A Multimodal Examination of Medial Parietal Cortex Contributions to Episodic Memory published pages: 8666-8679, ISSN: 0270-6474, DOI: 10.1523/jneurosci.1702-17.2018 |
The Journal of Neuroscience 38/40 | 2020-01-27 |
| 2019 |
Anders M. Fjell, Markus H. Sneve, Donatas Sederevicius, Øystein Sørensen, Stine K. Krogsrud, Athanasia M. Mowinckel, Kristine B. Walhovd Volumetric and microstructural regional changes of the hippocampus underlying development of recall performance after extended retention intervals published pages: 100723, ISSN: 1878-9293, DOI: 10.1016/j.dcn.2019.100723 |
Developmental Cognitive Neuroscience 40 | 2020-01-27 |
| 2019 |
Inge K. Amlien, Markus H. Sneve, Didac Vidal-Piñeiro, Kristine B. Walhovd, Anders M. Fjell Elaboration Benefits Source Memory Encoding Through Centrality Change published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-019-39999-1 |
Scientific Reports 9/1 | 2020-01-27 |
| 2019 |
Anders M Fjell, Øystein Sørensen, Inge K Amlien, David Bartrés-Faz, Didac Maciá Bros, Nikolaus Buchmann, Ilja Demuth, Christian A Drevon, Sandra Düzel, Klaus P Ebmeier, Ane-Victoria Idland, Tim C Kietzmann, Rogier Kievit, Simone Kühn, Ulman Lindenberger, Athanasia M Mowinckel, Lars Nyberg, Darren Price, Claire E Sexton, Cristina Solé-Padullés, Sara Pudas, Donatas Sederevicius, Sana Suri, G Self-reported sleep relates to hippocampal atrophy across the adult lifespan – results from the Lifebrain consortium published pages: , ISSN: 0161-8105, DOI: 10.1093/sleep/zsz280 |
Sleep | 2020-01-27 |
| 2018 |
Didac Vidal-Piñeiro, Markus H Sneve, Lars H Nyberg, Athanasia M Mowinckel, Donatas Sederevicius, Kristine B Walhovd, Anders M Fjell Maintained Frontal Activity Underlies High Memory Function Over 8 Years in Aging published pages: , ISSN: 1047-3211, DOI: 10.1093/cercor/bhy177 |
Cerebral Cortex | 2019-05-23 |
| 2017 |
Didac Vidal-Piñeiro, Markus H. Sneve, Andreas B. Storsve, James M. Roe, Kristine B. Walhovd, Anders M. Fjell Neural correlates of durable memories across the adult lifespan: brain activity at encoding and retrieval published pages: 20-33, ISSN: 0197-4580, DOI: 10.1016/j.neurobiolaging.2017.08.017 |
Neurobiology of Aging 60 | 2019-05-23 |
| 2018 |
Espen Langnes, Didac Vidal-Piñeiro, Markus H Sneve, Inge K Amlien, Kristine B Walhovd, Anders M Fjell Development and Decline of the Hippocampal Long-Axis Specialization and Differentiation During Encoding and Retrieval of Episodic Memories published pages: , ISSN: 1047-3211, DOI: 10.1093/cercor/bhy209 |
Cerebral Cortex | 2019-05-23 |
| 2018 |
Anders M Fjell, Chi-Hua Chen, Donatas Sederevicius, Markus H Sneve, Håkon Grydeland, Stine K Krogsrud, Inge Amlien, Lia Ferschmann, Hedda Ness, Line Folvik, Dani Beck, Athanasia M Mowinckel, Christian K Tamnes, René Westerhausen, Asta K Håberg, Anders M Dale, Kristine B Walhovd Continuity and Discontinuity in Human Cortical Development and Change From Embryonic Stages to Old Age published pages: , ISSN: 1047-3211, DOI: 10.1093/cercor/bhy266 |
Cerebral Cortex | 2019-05-23 |
| 2018 |
Markus H Sneve, Håkon Grydeland, Marcello G P Rosa, Tomáš Paus, Tristan Chaplin, Kristine Walhovd, Anders M Fjell High-Expanding Regions in Primate Cortical Brain Evolution Support Supramodal Cognitive Flexibility published pages: , ISSN: 1047-3211, DOI: 10.1093/cercor/bhy268 |
Cerebral Cortex | 2019-05-23 |
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "AGECONSOLIDATE" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "AGECONSOLIDATE" are provided by the European Opendata Portal: CORDIS opendata.