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ErasmusBlink

ErasmusBlink: A low cost and easy to use measurement system for medical research with diagnostic potential

Total Cost €

EC-Contrib. €

Partnership

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ErasmusBlink project word cloud

Explore the words cloud of the ErasmusBlink project. It provides you a very rough idea of what is the project "ErasmusBlink" about.

academic platform solid pharmaceutical customer disciplines species memory animals successful prepare shown humans erasmusblink detect clinical deficits correlations scientific setup neuroscientists collaborations acquire market care erc recording setups virtually industrial functional skills commercialization requirement daily serve programming poc diseases purposes cover physiological eyeblink reproducible medical conditioning clinicians behavioral basic neurosciences extremely mechanisms nutritional commercially noldus sciences life players survey tests first wearable alleviating neurological psychiatric uncover total fundamental experiments learning

Project "ErasmusBlink" data sheet

The following table provides information about the project.

Coordinator	ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Organization address address: DR MOLEWATERPLEIN 40 city: ROTTERDAM postcode: 3015 GD website: www.erasmusmc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Netherlands [NL]
Total cost	149˙938 €
EC max contribution	149˙938 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2016-PoC
Funding Scheme	ERC-POC
Starting year	2017
Duration (year-month-day)	from 2017-09-01 to 2018-08-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Organization address address: DR MOLEWATERPLEIN 40 city: ROTTERDAM postcode: 3015 GD website: www.erasmusmc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ROTTERDAM)	coordinator	149˙938.00

Map

Project objective

Neuroscientists and clinicians use a wide range of behavioral tests to investigate the physiological mechanisms of learning and memory formation. One of the most objective and reliable tests is eyeblink conditioning, as it is extremely simple, it can be done in both humans and animals, it measures many aspects of how we learn in our daily life, and it can detect memory deficits in many neurological and psychiatric diseases. However, so far there are no low-cost reliable eyeblink conditioning setups commercially available. Therefore, we propose for this ERC-POC application to prepare the commercialization of ErasmusBlink as a low-cost, wearable eyeblink conditioning recording and analysis setup that can be used in virtually all species. With ErasmusBlink one can do reliable and reproducible eyeblink conditioning experiments for scientific, medical and industrial purposes. ErasmusBlink will be the first ‘total care’ package, alleviating the potential customer from the requirement of the technical and programming skills, which one currently needs to acquire before being able to do eyeblink conditioning experiments. Our market survey will cover three major fields: Basic neurosciences (1), clinical and pharmaceutical research (2), and nutritional sciences (3). For all three fields eyeblink conditioning parameters have been shown to uncover important and fundamental functional processes and correlations. Our current academic collaborations with key players in each of these disciplines and with industrial partners like Noldus IT serve as a solid platform to ensure a successful commercialization of ErasmusBlink.

Publications

List of publications.
year	authors and title	journal	last update
2019	M.M. ten Brinke, H.J. Boele, C.I. De Zeeuw Conditioned climbing fiber responses in cerebellar cortex and nuclei published pages: 26-36, ISSN: 0304-3940, DOI: 10.1016/j.neulet.2018.04.035	Neuroscience Letters 688	2019-05-28
2016	Hille Koppen, Henk-Jan Boele, Inge H Palm-Meinders, Bastiaan J Koutstaal, Corinne GC Horlings, Bas K Koekkoek, Jos van der Geest, Albertine E Smit, Mark A van Buchem, Lenore J Launer, Gisela M Terwindt, Bas R Bloem, Mark C Kruit, Michel D Ferrari, Chris I De Zeeuw Cerebellar function and ischemic brain lesions in migraine patients from the general population published pages: 177-190, ISSN: 0333-1024, DOI: 10.1177/0333102416643527	Cephalalgia 37/2	2019-05-28
2018	Gili Ezra-Nevo, Francesca Prestori, Francesca Locatelli, Teresa Soda, Michiel M. ten Brinke, Mareen Engel, Henk-Jan Boele, Laura Botta, Dena Leshkowitz, Assaf Ramot, Michael Tsoory, Inbal E. Biton, Jan Deussing, Egidio D\'Angelo, Chris I. De Zeeuw, Alon Chen Cerebellar Learning Properties Are Modulated by the CRF Receptor published pages: 6751-6765, ISSN: 0270-6474, DOI: 10.1523/JNEUROSCI.3106-15.2018	The Journal of Neuroscience 38/30	2019-05-28
2018	Devika Narain, Evan D. Remington, Chris I. De Zeeuw, Mehrdad Jazayeri A cerebellar mechanism for learning prior distributions of time intervals published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-017-02516-x	Nature Communications 9/1	2019-05-28
2017	Karolina LÃ¶wgren, Rasmus BÃ¥Ã¥th, Anders Rasmussen, Henk-Jan Boele, Sebastiaan K. E. Koekkoek, Chris I. De Zeeuw, Germund Hesslow Performance in eyeblink conditioning is age and sex dependent published pages: e0177849, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0177849	PLOS ONE 12/5	2019-05-28
2017	Thomas M. Ernst, Markus ThÃ¼rling, Sarah MÃ¼ller, Fabian Kahl, Stefan Maderwald, Marc Schlamann, Henk-Jan Boele, Sebastiaan K. E. Koekkoek, JÃ¶rn Diedrichsen, Chris I. De Zeeuw, Mark E. Ladd, Dagmar Timmann Modulation of 7Â T fMRI Signal in the Cerebellar Cortex and Nuclei During Acquisition, Extinction, and Reacquisition of Conditioned Eyeblink Responses published pages: 3957-3974, ISSN: 1065-9471, DOI: 10.1002/hbm.23641	Human Brain Mapping 38/8	2019-05-28
2018	Anders Rasmussen, Anna C.H.G. Ijpelaar, Chris I. De Zeeuw, Henk-Jan Boele Caffeine has no effect on eyeblink conditioning in mice published pages: 252-255, ISSN: 0166-4328, DOI: 10.1016/j.bbr.2017.09.013	Behavioural Brain Research 337	2019-05-28
2017	Michiel M ten Brinke, Shane A Heiney, Xiaolu Wang, Martina Proietti-Onori, Henk-Jan Boele, Jacob Bakermans, Javier F Medina, Zhenyu Gao, Chris I De Zeeuw Dynamic modulation of activity in cerebellar nuclei neurons during pavlovian eyeblink conditioning in mice published pages: , ISSN: 2050-084X, DOI: 10.7554/eLife.28132	eLife 6	2019-05-28
2017	Andrea Giovannucci, Aleksandra Badura, Ben Deverett, Farzaneh Najafi, Talmo D Pereira, Zhenyu Gao, Ilker Ozden, Alexander D Kloth, Eftychios Pnevmatikakis, Liam Paninski, Chris I De Zeeuw, Javier F Medina, Samuel S-H Wang Cerebellar granule cells acquire a widespread predictive feedback signal during motor learning published pages: 727-734, ISSN: 1097-6256, DOI: 10.1038/nn.4531	Nature Neuroscience 20/5	2019-05-28

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The information about "ERASMUSBLINK" are provided by the European Opendata Portal: CORDIS opendata.