Explore the words cloud of the LYSOCIL project. It provides you a very rough idea of what is the project "LYSOCIL" about.
The following table provides information about the project.
Coordinator |
UNIVERSIDADE NOVA DE LISBOA
Organization address contact info |
Coordinator Country | Portugal [PT] |
Total cost | 967˙572 € |
EC max contribution | 967˙572 € (100%) |
Programme |
1. H2020-EU.4.b. (Twinning of research institutions) |
Code Call | H2020-WIDESPREAD-05-2017-Twinning |
Funding Scheme | CSA |
Starting year | 2018 |
Duration (year-month-day) | from 2018-11-01 to 2021-10-31 |
Take a look of project's partnership.
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1 | UNIVERSIDADE NOVA DE LISBOA | PT (LISBOA) | coordinator | 626˙878.00 |
2 | FONDAZIONE TELETHON | IT (ROMA) | participant | 183˙068.00 |
3 | WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER | DE (MUENSTER) | participant | 157˙625.00 |
The high diversity, low numbers and scattered distribution of patients affected rare diseases (RDs) represent a big challenge for biomedical research and health care, the patients and their families. International cooperation is paramount to understand the etiology and find better diagnostic procedures for RDs. LYSOCIL addresses that need through a scientific strategy to reinforce research and innovation excellence in the study of lysosomal diseases and ciliopathies, with a special attention on the diagnosis and etiology of these diseases. The Chronic Diseases Research Center of the NOVA Medical School (UNL-NMS-CEDOC) aims to be at the forefront of European and international scientific excellence in chronic RDs. Towards this goal, UNL-NMS-CEDOC is twinning with two internationally leading research institutions, the Münster University (WWU) and the Telethon Institute of Genetics and Medicine (TIGEM - FTELE.IGM). LYSOCIL will leverage on WWU and TIGEM’s outstanding multidisciplinary knowledge and experience, research and training best practices, as well as collaborative networks to enhance the research capacity and innovation potential of CEDOC-NMS. LYSOCIL is an integrated network of interactions (exchange and training of researchers, satellite meetings, Winter Retreats, virtual think tanks, etc.), articulated with the individual and joint scientific agendas of the partners, to power the research capacity of CEDOC-NMS and of its local and national ecosystems. LYSOCIL expects to increase by 20% in multiple indicators by 2021, including the number of citations; h-index of UNL-NMS-CEDOC researchers; percentage of publications in top impact journals; number of international collaborations and publications. By stimulating novel and long-lasting interactions between UNL-NMS-CEDOC, WWU and TIGEM (FTELE.GM) l unlock the research potential within and outside CEDOC-NMS, with an overall increase in the Portuguese and European RD research competitiveness.
year | authors and title | journal | last update |
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2019 |
Carole Oudot, Andreia Gomes, Valérie Nicolas, Morgane Le Gall, Philippe Chaffey, Cédric Broussard, Giuseppe Calamita, Maria Mastrodonato, Patrizia Gena, Jean-Luc Perfettini, Jocelyne Hamelin, Antoinette Lemoine, Rodolphe Fischmeister, Helena L.A. Vieira, Claudia N. Santos, Catherine Brenner CSRP3 mediates polyphenols-induced cardioprotection in hypertension published pages: 29-42, ISSN: 0955-2863, DOI: 10.1016/j.jnutbio.2019.01.001 |
The Journal of Nutritional Biochemistry 66 | 2020-04-01 |
2019 |
David J. Smith, Thomas D. Montenegro-Johnson, Susana S. Lopes Symmetry-Breaking Cilia-Driven Flow in Embryogenesis published pages: 105-128, ISSN: 0066-4189, DOI: 10.1146/annurev-fluid-010518-040231 |
Annual Review of Fluid Mechanics 51/1 | 2020-04-01 |
2019 |
Martin D. Burkhalter, Arthi Sridhar, Pedro Sampaio, Raquel Jacinto, Martina S. Burczyk, Cornelia Donow, Max Angenendt, Maja Hempel, Paul Walther, Petra Pennekamp, Heymut Omran, Susana S. Lopes, Stephanie M. Ware, Melanie Philipp Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis published pages: 2841-2855, ISSN: 0021-9738, DOI: 10.1172/jci98890 |
Journal of Clinical Investigation 129/7 | 2020-04-01 |
2019 |
Daniel Noronha Osório, Ricardo Viana-Soares, João Pedro Marto, Marcelo D. Mendonça, Hugo P. Silva, Cláudia Quaresma, Miguel Viana-Baptista, Hugo Gamboa, Helena L. A. Vieira Autonomic nervous system response to remote ischemic conditioning: heart rate variability assessment published pages: , ISSN: 1471-2261, DOI: 10.1186/s12872-019-1181-5 |
BMC Cardiovascular Disorders 19/1 | 2020-04-01 |
2019 |
Cláudia Figueiredo-Pereira, Regina Menezes, Sofia Ferreira, Cláudia N Santos, Helena L A Vieira Carbon monoxide released by CORM-A1 prevents yeast cell death via autophagy stimulation published pages: , ISSN: 1567-1364, DOI: 10.1093/femsyr/foz051 |
FEMS Yeast Research 19/5 | 2020-04-01 |
2019 |
Paolo Sanzà , Richard D. Evans, Deborah A. Briggs, Marta Cantero, Lluis Montoliu, Shyamal Patel, Elena V. Sviderskaya, Aymelt Itzen, Ana C. Figueiredo, Miguel C. Seabra, Alistair N. Hume Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a published pages: jcs212035, ISSN: 0021-9533, DOI: 10.1242/jcs.212035 |
Journal of Cell Science 132/9 | 2020-04-01 |
2019 |
Mahmoud R. Fassad, Mitali P. Patel, Amelia Shoemark, Thomas Cullup, Jane Hayward, Mellisa Dixon, Andrew V. Rogers, Sarah Ollosson, Claire Jackson, Patricia Goggin, Robert A. Hirst, Andrew Rutman, James Thompson, Lucy Jenkins, Paul Aurora, Eduardo Moya, Philip Chetcuti, Chris O\'Callaghan, Deborah J Morris-Rosendahl, Christopher M. Watson, Robert Wilson, Siobhan Carr, Woolf Walker, Andreia Pitno, Su Clinical utility of NGS diagnosis and disease stratification in a multiethnic primary ciliary dyskinesia cohort published pages: jmedgenet-2019-1, ISSN: 0022-2593, DOI: 10.1136/jmedgenet-2019-106501 |
Journal of Medical Genetics | 2020-04-01 |
2019 |
Matthew J. Hayes, Thomas Burgoyne, Silene T. Wavre-Shapton, Tanya Tolmachova, Miguel C. Seabra, Clare E. Futter Remodeling of the Basal Labyrinth of Retinal Pigment Epithelial Cells With Osmotic Challenge, Age, and Disease published pages: 2515, ISSN: 1552-5783, DOI: 10.1167/iovs.19-26784 |
Investigative Opthalmology & Visual Science 60/7 | 2020-04-01 |
2019 |
Stefanie Kuhns, CecÃlia Seixas, Sara Pestana, Bárbara Tavares, Renata Nogueira, Raquel Jacinto, José S Ramalho, Jeremy C Simpson, Jens S Andersen, Arnaud Echard, Susana S Lopes, Duarte C Barral, Oliver E Blacque Rab35 controls cilium length, function and membrane composition published pages: , ISSN: 1469-221X, DOI: 10.15252/embr.201847625 |
EMBO reports 20/10 | 2020-04-01 |
2019 |
Hugo Moreiras, Francisco J. C. Pereira, Matilde V. Neto, Liliana Bentoâ€Lopes, Tiago C. Festas, Miguel C. Seabra, Duarte C. Barral The exocyst is required for melanin exocytosis from melanocytes and transfer to keratinocytes published pages: 366-371, ISSN: 1755-1471, DOI: 10.1111/pcmr.12840 |
Pigment Cell & Melanoma Research 33/2 | 2020-04-01 |
2019 |
Elisabeth M. Storck, Julia Morales-Sanfrutos, Remigiusz A. Serwa, Nattawadee Panyain, Thomas Lanyon-Hogg, Tanya Tolmachova, Leandro N. Ventimiglia, Juan Martin-Serrano, Miguel C. Seabra, Beata Wojciak-Stothard, Edward W. Tate Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics published pages: 552-561, ISSN: 1755-4330, DOI: 10.1038/s41557-019-0237-6 |
Nature Chemistry 11/6 | 2020-04-01 |
2019 |
Cristina Casalou, Alexandra Faustino, Fernanda Silva, Inês C. Ferreira, Daniela Vaqueirinho, Andreia Ferreira, Pedro Castanheira, Teresa Barona, José S. Ramalho, Jacinta Serpa, Ana Félix, Duarte C. Barral Arl13b Regulates Breast Cancer Cell Migration and Invasion by Controlling Integrin-Mediated Signaling published pages: 1461, ISSN: 2072-6694, DOI: 10.3390/cancers11101461 |
Cancers 11/10 | 2020-04-01 |
2019 |
Hugo Moreiras, Mafalda Lopesâ€daâ€Silva, Miguel C. Seabra, Duarte C. Barral Melanin processing by keratinocytes: A nonâ€microbial type of hostâ€pathogen interaction? published pages: 301-304, ISSN: 1398-9219, DOI: 10.1111/tra.12638 |
Traffic 20/4 | 2020-04-01 |
2015 |
Cláudia S F Queiroga, Alessandro Vercelli, Helena L A Vieira Carbon monoxide and the CNS: challenges and achievements published pages: 1533-1545, ISSN: 0007-1188, DOI: 10.1111/bph.12729 |
British Journal of Pharmacology 172/6 | 2019-05-23 |
2015 |
Sara R. Oliveira, Helena L.A. Vieira, Carlos B. Duarte Effect of carbon monoxide on gene expression in cerebrocortical astrocytes: Validation of reference genes for quantitative real-time PCR published pages: 80-89, ISSN: 1089-8603, DOI: 10.1016/j.niox.2015.07.003 |
Nitric Oxide 49 | 2019-05-23 |
2015 |
Ana S. Almeida, Cláudia Figueiredo-Pereira, Helena L. A. Vieira Carbon monoxide and mitochondria – modulation of cell metabolism, redox response and cell death published pages: , ISSN: 1664-042X, DOI: |
Frontiers in Physiology 6 | 2019-05-23 |
2015 |
Sara R. Oliveira, Cláudia S. F. Queiroga, Helena L. A. Vieira Mitochondria and carbon monoxide: cytoprotection and control of cell metabolism - a role for Ca2+? published pages: , ISSN: 0022-3751, DOI: |
The Journal of Physiology | 2019-05-23 |
2015 |
Thomas Burgoyne, Ingrid P. Meschede, Jemima J. Burden, Maryse Bailly, Miguel C. Seabra, Clare E. Futter Rod disc renewal occurs by evagination of the ciliary plasma membrane that makes cadherin-based contacts with the inner segment published pages: 15922-15927, ISSN: 0027-8424, DOI: 10.1073/pnas.1509285113 |
Proceedings of the National Academy of Sciences 112/52 | 2019-05-03 |
2016 |
Otilia V. Vieira Rab3a and Rab10 are regulators of lysosome exocytosis and plasma membrane repair published pages: 349-351, ISSN: 2154-1248, DOI: 10.1080/21541248.2016.1235004 |
Small GTPases 9/4 | 2019-05-03 |
2018 |
Nanna Dreyer-Andersen, Ana Sofia Almeida, Pia Jensen, Morad Kamand, Justyna Okarmus, Tine Rosenberg, Stig Düring Friis, Alberto MartÃnez Serrano, Morten Blaabjerg, Bjarne Winther Kristensen, Troels Skrydstrup, Jan Bert Gramsbergen, Helena L. A. Vieira, Morten Meyer Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells published pages: e0191207, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0191207 |
PLOS ONE 13/1 | 2019-05-03 |
2018 |
Mark S. Gibson, Neuza Domingues, Otilia V. Vieira Lipid and Non-lipid Factors Affecting Macrophage Dysfunction and Inflammation in Atherosclerosis published pages: , ISSN: 1664-042X, DOI: 10.3389/fphys.2018.00654 |
Frontiers in Physiology 9 | 2019-05-03 |
2018 |
Rita Gorgulho, Raquel Jacinto, Susana S. Lopes, Sofia A. Pereira, Erin M. Tranfield, Gabriel G. Martins, Emilio J. Gualda, Rico J. E. Derks, Ana C. Correia, Evelyne Steenvoorden, Petra Pintado, Oleg A. Mayboroda, Emilia C. Monteiro, Judit Morello Usefulness of zebrafish larvae to evaluate drug-induced functional and morphological renal tubular alterations published pages: 411-423, ISSN: 0340-5761, DOI: 10.1007/s00204-017-2063-1 |
Archives of Toxicology 92/1 | 2019-05-03 |
2017 |
Florent Ubelmann, Tatiana Burrinha, Laura Salavessa, Ricardo Gomes, Cláudio Ferreira, Nuno Moreno, Cláudia Guimas Almeida Bin1 and CD2AP polarise the endocytic generation of betaâ€amyloid published pages: 102-122, ISSN: 1469-221X, DOI: 10.15252/embr.201642738 |
EMBO reports 18/1 | 2019-05-03 |
2018 |
Mathias J. Gerl, Winchil L. C. Vaz, Neuza Domingues, Christian Klose, Michal A. Surma, Júlio L. Sampaio, Manuel S. Almeida, Gustavo Rodrigues, Pedro Araújo-Gonçalves, Jorge Ferreira, Claudia Borbinha, João Pedro Marto, Miguel Viana-Baptista, Kai Simons, Otilia V. Vieira Cholesterol is Inefficiently Converted to Cholesteryl Esters in the Blood of Cardiovascular Disease Patients published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-33116-4 |
Scientific Reports 8/1 | 2019-05-03 |
2018 |
Judit Morello, Rico J. E. Derks, Susana S. Lopes, Evelyne Steenvoorden, Emilia C. Monteiro, Oleg A. Mayboroda, Sofia A. Pereira Zebrafish Larvae Are a Suitable Model to Investigate the Metabolic Phenotype of Drug-Induced Renal Tubular Injury published pages: , ISSN: 1663-9812, DOI: 10.3389/fphar.2018.01193 |
Frontiers in Pharmacology 9 | 2019-05-03 |
2018 |
Sandra I. Anjo, Tania Martins-Marques, Paulo Pereira, Henrique Girão, Bruno Manadas Elucidation of the dynamic nature of interactome networks: A practical tutorial published pages: 116-126, ISSN: 1874-3919, DOI: 10.1016/j.jprot.2017.04.011 |
Journal of Proteomics 171 | 2019-05-03 |
2017 |
Florent Ubelmann, Tatiana Burrinha, Cláudia Guimas Almeida A Novel Protocol to Quantitatively Measure the Endocytic Trafficking of Amyloid Precursor Protein (APP) in Polarized Primary Neurons with Sub-cellular Resolution published pages: , ISSN: 2331-8325, DOI: 10.21769/BioProtoc.2629 |
BIO-PROTOCOL 7/23 | 2019-05-03 |
2017 |
Steve Catarino, Paulo Pereira, Henrique Girão Molecular control of chaperone-mediated autophagy published pages: 663-674, ISSN: 0071-1365, DOI: 10.1042/EBC20170057 |
Essays In Biochemistry 61/6 | 2019-05-03 |
2017 |
Ana Rita Ramalho, Adriana Toscano, Paulo Pereira, Henrique Girão, Lino Gonçalves, Carla Marques Hyperglycemia-induced degradation of HIF-1α contributes to impaired response of cardiomyocytes to hypoxia published pages: 367-373, ISSN: 0870-2551, DOI: 10.1016/j.repc.2016.09.018 |
Revista Portuguesa de Cardiologia 36/5 | 2019-05-03 |
2018 |
Bettina Winckler, Victor Faundez, Sandra Maday, Qian Cai, Cláudia Guimas Almeida, Huaye Zhang The Endolysosomal System and Proteostasis: From Development to Degeneration published pages: 9364-9374, ISSN: 0270-6474, DOI: 10.1523/JNEUROSCI.1665-18.2018 |
The Journal of Neuroscience 38/44 | 2019-05-03 |
2018 |
Sara R. Oliveira, Cláudia Figueiredo-Pereira, Carlos B. Duarte, Helena L. A. Vieira P2X7 Receptors Mediate CO-Induced Alterations in Gene Expression in Cultured Cortical Astrocytes—Transcriptomic Study published pages: , ISSN: 0893-7648, DOI: 10.1007/s12035-018-1302-7 |
Molecular Neurobiology | 2019-05-03 |
2017 |
P. Pintado, P. Sampaio, B. Tavares, T. D. Montenegro-Johnson, D. J. Smith, S. S. Lopes Dynamics of cilia length in left–right development published pages: 161102, ISSN: 2054-5703, DOI: 10.1098/rsos.161102 |
Royal Society Open Science 4/3 | 2019-05-03 |
2018 |
Claudia N. Santos, Andreia Gomes, Carole Oudot, Daniela Dias-Pedroso, Ana Rodriguez-Mateos, Helena L.A. Vieira, Catherine Brenner Pure Polyphenols Applications for Cardiac Health and Disease published pages: 2137-2156, ISSN: 1381-6128, DOI: 10.2174/1381612824666180608102344 |
Current Pharmaceutical Design 24/19 | 2019-05-03 |
2017 |
Florent Ubelmann, Tatiana Burrinha, Cláudia Guimas Almeida Measuring the Endocytic Recycling of Amyloid Precursor Protein (APP) in Neuro2a Cells published pages: , ISSN: 2331-8325, DOI: 10.21769/BioProtoc.2635 |
BIO-PROTOCOL 7/23 | 2019-05-03 |
2018 |
Elsa Seixas, Cristina Escrevente, Miguel C. Seabra, Duarte C. Barral Rab GTPase regulation of bacteria and protozoa phagocytosis occurs through the modulation of phagocytic receptor surface expression published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-31171-5 |
Scientific Reports 8/1 | 2019-05-03 |
2018 |
Cláudia Guimas Almeida, Farzaneh Sadat Mirfakhar, Catarina Perdigão, Tatiana Burrinha Impact of late-onset Alzheimer’s genetic risk factors on beta-amyloid endocytic production published pages: 2577-2589, ISSN: 1420-682X, DOI: 10.1007/s00018-018-2825-9 |
Cellular and Molecular Life Sciences 75/14 | 2019-05-03 |
2017 |
Barbara Tavares, Raquel Jacinto, Pedro Sampaio, Sara Pestana, Andreia Pinto, Andreia Vaz, Mónica Roxo-Rosa, Rui Gardner, Telma Lopes, Britta Schilling, Ian Henry, Leonor Saúde, Susana Santos Lopes Notch/Her12 signalling modulates, motile/immotile cilia ratio downstream of Foxj1a in zebrafish left-right organizer published pages: , ISSN: 2050-084X, DOI: 10.7554/eLife.25165 |
eLife 6 | 2019-05-03 |
2018 |
Ioannis S. Dimopoulos, Stephanie C. Hoang, Alina Radziwon, Natalia M. Binczyk, Miguel C. Seabra, Robert E. MacLaren, Rizwan Somani, Matthew T.S. Tennant, Ian M. MacDonald Two-Year Results After AAV2-Mediated Gene Therapy for Choroideremia: The Alberta Experience published pages: 130-142, ISSN: 0002-9394, DOI: 10.1016/j.ajo.2018.06.011 |
American Journal of Ophthalmology 193 | 2019-05-03 |
2015 |
Tânia Martins-Marques, Steve Catarino, Carla Marques, Paulo Pereira, Henrique Girão To beat or not to beat: degradation of Cx43 imposes the heart rhythm published pages: , ISSN: 0300-5127, DOI: |
Biochemical Society transactions | 2019-05-03 |
2018 |
Kanmin Xue, Jasleen K Jolly, Alun R. Barnard, Anna Rudenko, Anna P. Salvetti, Maria I. PatrÃcio, Thomas L. Edwards, Markus Groppe, Harry O. Orlans, Tanya Tolmachova, Graeme C. Black, Andrew R. Webster, Andrew J. Lotery, Graham E. Holder, Susan M. Downes, Miguel C. Seabra, Robert E. MacLaren Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia published pages: 1507-1512, ISSN: 1078-8956, DOI: 10.1038/s41591-018-0185-5 |
Nature Medicine 24/10 | 2019-05-03 |
2018 |
Ana S. Almeida, Nuno L. Soares, Catarina O. Sequeira, Sofia A. Pereira, Ursula Sonnewald, Helena L.A. Vieira Improvement of neuronal differentiation by carbon monoxide: Role of pentose phosphate pathway published pages: 338-347, ISSN: 2213-2317, DOI: 10.1016/j.redox.2018.05.004 |
Redox Biology 17 | 2019-05-03 |
2017 |
Rui Baptista, Carla Marques, Steve Catarino, Francisco J Enguita, Marina C Costa, Paulo Matafome, Mónica Zuzarte, Graça Castro, AbÃlio Reis, Pedro Monteiro, Mariano Pêgo, Paulo Pereira, Henrique Girão MicroRNA-424(322) as a new marker of disease progression in pulmonary arterial hypertension and its role in right ventricular hypertrophy by targeting SMURF1 published pages: 53-64, ISSN: 0008-6363, DOI: 10.1093/cvr/cvx187 |
Cardiovascular Research 114/1 | 2019-05-03 |
2015 |
Silène T. Wavre-Shapton, Alessandra A. Calvi, Mark Turmaine, Miguel C. Seabra, Daniel F. Cutler, Clare E. Futter, Hannah M. Mitchison Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease). published pages: , ISSN: 0964-6906, DOI: |
Human Molecular Genetics | 2019-05-03 |
2018 |
Daniela Dias-Pedroso, Joel Guerra, Andreia Gomes, Carole Oudot, Catherine Brenner, Cláudia N. Santos, Helena L. A. Vieira Phenolic Metabolites Modulate Cardiomyocyte Beating in Response to Isoproterenol published pages: , ISSN: 1530-7905, DOI: 10.1007/s12012-018-9485-8 |
Cardiovascular Toxicology | 2019-05-03 |
2019 |
J. Solowiej-Wedderburn, D.J. Smith, S.S. Lopes, T.D. Montenegro-Johnson Wall stress enhanced exocytosis of extracellular vesicles as a possible mechanism of left-right symmetry-breaking in vertebrate development published pages: 220-226, ISSN: 0022-5193, DOI: 10.1016/j.jtbi.2018.10.015 |
Journal of Theoretical Biology 460 | 2019-05-03 |
2016 |
Tania Martins-Marques, Maria Joao Pinho, Monica Zuzarte, Carla Oliveira, Paulo Pereira, Joost P. G. Sluijter, Celia Gomes, Henrique Girao Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin published pages: 32538, ISSN: 2001-3078, DOI: 10.3402/jev.v5.32538 |
Journal of Extracellular Vesicles 5/1 | 2019-05-03 |
2015 |
Marta Mauro-Lizcano, Lorena Esteban-MartÃnez, Esther Seco, Ana Serrano-Puebla, Lucia Garcia-Ledo, Cláudia Figueiredo-Pereira, Helena L A Vieira, Patricia Boya New method to assess mitophagy flux by flow cytometry published pages: 833-843, ISSN: 1554-8627, DOI: 10.1080/15548627.2015.1034403 |
Autophagy 11/5 | 2019-05-03 |
2018 |
Maria S. Correia, Hugo Moreiras, Francisco J.C. Pereira, Matilde V. Neto, Tiago C. Festas, Abul K. Tarafder, José S. Ramalho, Miguel C. Seabra, Duarte C. Barral Melanin Transferred to Keratinocytes Resides in Nondegradative Endocytic Compartments published pages: 637-646, ISSN: 0022-202X, DOI: 10.1016/j.jid.2017.09.042 |
Journal of Investigative Dermatology 138/3 | 2019-05-03 |
2015 |
Carolina Thielekeâ€Matos, Mafalda Lopes da Silva, Laura Cabritaâ€Santos, Martim D. Portal, Inês P. Rodrigues, Vanessa Zuzarteâ€Luis, José S. Ramalho, Clare E. Futter, Maria M. Mota, Duarte C. Barral, Miguel C. Seabra Host cell autophagy contributes to Plasmodium liver development published pages: , ISSN: 1462-5814, DOI: |
Cellular Microbiology | 2019-05-03 |
2016 |
Ângela S. Inácio, Neuza S. Domingues, Alexandra Nunes, PatrÃcia T. Martins, Maria J. Moreno, LuÃs M. Estronca, Rui Fernandes, António J. M. Moreno, Maria J. Borrego, João P. Gomes, Winchil L. C. Vaz, OtÃlia V. Vieira Quaternary ammonium surfactant structure determines selective toxicity towards bacteria: mechanisms of action and clinical implications in antibacterial prophylaxis published pages: 641-654, ISSN: 0305-7453, DOI: 10.1093/jac/dkv405 |
Journal of Antimicrobial Chemotherapy 71/3 | 2019-05-03 |
2016 |
Marisa Encarnação, LÃlia Espada, Cristina Escrevente, Denisa Mateus, José Ramalho, Xavier Michelet, Inês Santarino, Victor W. Hsu, Michael B. Brenner, Duarte C. Barral, OtÃlia V. Vieira A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair published pages: 631-640, ISSN: 0021-9525, DOI: 10.1083/jcb.201511093 |
The Journal of Cell Biology 213/6 | 2019-05-03 |
2016 |
Bret Wankel, Jiangyong Ouyang, Xuemei Guo, Krassimira Hadjiolova, Jeremy Miller, Yi Liao, Daniel Kai Long Tham, Rok Romih, Leonardo R. Andrade, Iwona Gumper, Jean-Pierre Simon, Rakhee Sachdeva, Tanya Tolmachova, Miguel C. Seabra, Mitsunori Fukuda, Nicole Schaeren-Wiemers, Wan Jin Hong, David D. Sabatini, Xue-Ru Wu, Xiangpeng Kong, Gert Kreibich, Michael J. Rindler, Tung-Tien Sun Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells published pages: 1621-1634, ISSN: 1059-1524, DOI: 10.1091/mbc.E15-04-0230 |
Molecular Biology of the Cell 27/10 | 2019-05-03 |
2016 |
Ângela S. Inácio, Alexandra Nunes, Catarina Milho, LuÃs Jaime Mota, Maria J. Borrego, João P. Gomes, Winchil L. C. Vaz, OtÃlia V. Vieira In vitro activity of quaternary ammonium surfactants against streptococcal, chlamydial, and gonococcal infective agents published pages: , ISSN: 0066-4804, DOI: |
Antimicrobial agents and chemotherapy | 2019-05-03 |
2016 |
Susana A. Gonçalves, Diana Macedo, Helena Raquel, Pedro D. Simões, Flaviano Giorgini, José S. Ramalho, Duarte C. Barral, LuÃs Ferreira Moita, Tiago Fleming Outeiro shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity published pages: e1005995, ISSN: 1553-7390, DOI: 10.1371/journal.pgen.1005995 |
PLOS Genetics 12/4 | 2019-05-03 |
2015 |
B. Walker, E. Schmid, A. Russo, E.-M. Schmidt, O. Burk, P. Münzer, A. Velic, B. Macek, M. Schaller, M. Schwab, M. C. Seabra, M. Gawaz, F. Lang, O. Borst Impact of the serum- and glucocorticoid-inducible kinase 1 on platelet dense granule biogenesis and secretion published pages: 1325-1334, ISSN: 1538-7933, DOI: 10.1111/jth.12998 |
Journal of Thrombosis and Haemostasis 13/7 | 2019-05-03 |
2015 |
Margaret Alexander, Ruozhen Hu, Marah C. Runtsch, Dominique A. Kagele, Timothy L. Mosbruger, Tanya Tolmachova, Miguel C. Seabra, June L. Round, Diane M. Ward, Ryan M. O’Connell Exosome-delivered microRNAs modulate the inflammatory response to endotoxin published pages: , ISSN: 2041-1723, DOI: 10.1038/ncomms8321 |
Nature Communications 6/1 | 2019-05-03 |
2015 |
Nadine Reichhart, Magdalena Markowski, Shimpei Ishiyama, Andrea Wagner, Sergio Crespo-Garcia, Talitha Schorb, José S. Ramalho, Vladimir M. Milenkovic, Renate Föckler, Miguel C. Seabra, Olaf Strauß Rab27a GTPase modulates L-type Ca(2+) channel function via interaction with the II-III linker of CaV1.3 subunit. published pages: , ISSN: 0898-6568, DOI: |
Cellular Signalling | 2019-05-03 |
2015 |
T. Burgoyne, M. N. O\'Connor, M. C. Seabra, D. F. Cutler, C. E. Futter Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL published pages: 1400-1407, ISSN: 0021-9533, DOI: 10.1242/jcs.164400 |
Journal of Cell Science 128/7 | 2019-05-03 |
2016 |
Cristina Casalou, Alexandra Faustino, Duarte C. Barral Arf proteins in cancer cell migration published pages: 270-282, ISSN: 2154-1248, DOI: 10.1080/21541248.2016.1228792 |
Small GTPases 7/4 | 2019-05-03 |
2016 |
Thomas L. Edwards, Jasleen K. Jolly, Markus Groppe, Alun R. Barnard, Charles L. Cottriall, Tanya Tolmachova, Graeme C. Black, Andrew R. Webster, Andrew J. Lotery, Graham E. Holder, Kanmin Xue, Susan M. Downes, Matthew P. Simunovic, Miguel C. Seabra, Robert E. MacLaren Visual Acuity after Retinal Gene Therapy for Choroideremia published pages: 1996-1998, ISSN: 0028-4793, DOI: 10.1056/NEJMc1509501 |
New England Journal of Medicine 374/20 | 2019-05-03 |
2016 |
Ana S. Almeida, Nuno L. Soares, Melissa Vieira, Jan Bert Gramsbergen, Helena L. A. Vieira Carbon Monoxide Releasing Molecule-A1 (CORM-A1) Improves Neurogenesis: Increase of Neuronal Differentiation Yield by Preventing Cell Death published pages: e0154781, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0154781 |
PLOS ONE 11/5 | 2019-05-03 |
2016 |
Daniela Pedroso, Ana R. Nunes, LucÃlia N. Diogo, Carole Oudot, EmÃlia C. Monteiro, Catherine Brenner, Helena L.A. Vieira Hippocampal neurogenesis response: What can we expect from two different models of hypertension? published pages: 199-206, ISSN: 0006-8993, DOI: 10.1016/j.brainres.2016.05.044 |
Brain Research 1646 | 2019-05-03 |
2015 |
Quanlong Lu, Christine Insinna, Carolyn Ott, Jimmy Stauffer, Petra A. Pintado, Juliati Rahajeng, Ulrich Baxa, Vijay Walia, Adrian Cuenca, Yoo-Seok Hwang, Ira O. Daar, Susana Lopes, Jennifer Lippincott-Schwartz, Peter K. Jackson, Steve Caplan, Christopher J. Westlake Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation published pages: 228-240, ISSN: 1465-7392, DOI: 10.1038/ncb3109 |
Nature Cell Biology 17/3 | 2019-05-03 |
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Tânia Martins-Marques, Steve Catarino, Carla Marques, Paulo Matafome, Teresa Ribeiro-Rodrigues, Rui Baptista, Paulo Pereira, Henrique Girão Heart ischemia results in connexin43 ubiquitination localized at the intercalated discs published pages: 196-201, ISSN: 0300-9084, DOI: 10.1016/j.biochi.2015.02.020 |
Biochimie 112 | 2019-05-03 |
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Daniel J Klionsky, Kotb Abdelmohsen, Akihisa Abe, Md Joynal Abedin, Hagai Abeliovich, Abraham Acevedo Arozena, Hiroaki Adachi, Christopher M Adams, Peter D Adams, Khosrow Adeli, Peter J Adhihetty, Sharon G Adler, Galila Agam, Rajesh Agarwal, Manish K Aghi, Maria Agnello, Patrizia Agostinis, Patricia V Aguilar, Julio Aguirre-Ghiso, Edoardo M Airoldi, Slimane Ait-Si-Ali, Takahiko Akematsu, Emmanuel T Akporiaye, Mohamed Al-Rubeai, Guillermo M Albaiceta, Chris Albanese, Diego Albani, Matthew L Albert, Jesus Aldudo, Hana Algül, Mehrdad Alirezaei, Iraide Alloza, Alexandru Almasan, Maylin Almonte-Beceril, Emad S Alnemri, Covadonga Alonso, Nihal Altan-Bonnet, Dario C Altieri, Silvia Alvarez, Lydia Alvarez-Erviti, Sandro Alves, Giuseppina Amadoro, Atsuo Amano, Consuelo Amantini, Santiago Ambrosio, Ivano Amelio, Amal O Amer, Mohamed Amessou, Angelika Amon, Zhenyi An, Frank A Anania, Stig U Andersen, Usha P Andley, Catherine K Andreadi, Nathalie Andrieu-Abadie, Alberto Anel, David K Ann, Shailendra Anoopkumar-Dukie, Manuela Antonioli, Hiroshi Aoki, Nadezda Apostolova, Saveria Aquila, Katia Aquilano, Koichi Araki, Eli Arama, Agustin Aranda, Jun Araya, Alexandre Arcaro, Esperanza Arias, Hirokazu Arimoto, Aileen R Ariosa, Jane L Armstrong, Thierry Arnould, Ivica Arsov, Katsuhiko Asanuma, Valerie Askanas, Eric Asselin, Ryuichiro Atarashi, Sally S Atherton, Julie D Atkin, Laura D Attardi, Patrick Auberger, Georg Auburger, Laure Aurelian, Riccardo Autelli, Laura Avagliano, Maria Laura Avantaggiati, Limor Avrahami, Suresh Awale, Neelam Azad, Tiziana Bachetti, Jonathan M Backer, Dong-Hun Bae, Jae-sung Bae, Ok-Nam Bae, Soo Han Bae, Eric H Baehrecke, Seung-Hoon Baek, Stephen Baghdiguian, Agnieszka Bagniewska-Zadworna, Hua Bai, Jie Bai, Xue-Yuan Bai, Yannick Bailly, Kithiganahalli Narayanaswamy Balaji, Walter Balduini, Andrea Ballabio, Rena Balzan, Rajkumar Banerjee, Gábor Bánhegyi, Haijun Bao, Benoit Barbeau, Maria D Barrachina, Esther Barreiro, Bonnie Bartel, Alberto Bartolomé, Diane C Bassham, Maria Teresa Bassi, Robert C Bast, Alakananda Basu, Maria Teresa Batista, Henri Batoko, Maurizio Battino, Kyle Bauckman, Bradley L Baumgarner, K Ulrich Bayer, Rupert Beale, Jean-François Beaulieu, George R. Beck, Christoph Becker, J David Beckham, Pierre-André Bédard, Patrick J Bednarski, Thomas J Begley, Christian Behl, Christian Behrends, Georg MN Behrens, Kevin E Behrns, Eloy Bejarano, Amine Belaid, Francesca Belleudi, Giovanni Bénard, Guy Berchem, Daniele Bergamaschi, Matteo Bergami, Ben Berkhout, Laura Berliocchi, Amélie Bernard, Monique Bernard, Francesca Bernassola, Anne Bertolotti, Amanda S Bess, Sébastien Besteiro, Saverio Bettuzzi, Savita Bhalla, Shalmoli Bhattacharyya, Sujit K Bhutia, Caroline Biagosch, Michele Wolfe Bianchi, Martine Biard-Piechaczyk, Viktor Billes, Claudia Bincoletto, Baris Bingol, Sara W Bird, Marc Bitoun, Ivana Bjedov, Craig Blackstone, Lionel Blanc, Guillermo A Blanco, Heidi Kiil Blomhoff, Emilio Boada-Romero, Stefan Böckler, Marianne Boes, Kathleen Boesze-Battaglia, Lawrence H Boise, Alessandra Bolino, Andrea Boman, Paolo Bonaldo, Matteo Bordi, Jürgen Bosch, Luis M Botana, Joelle Botti, German Bou, Marina Bouché, Marion Bouchecareilh, Marie-Josée Boucher, Michael E Boulton, Sebastien G Bouret, Patricia Boya, Michaël Boyer-Guittaut, Peter V Bozhkov, Nathan Brady, Vania MM Braga, Claudio Brancolini, Gerhard H Braus, José M Bravo-San Pedro, Lisa A Brennan, Emery H Bresnick, Patrick Brest, Dave Bridges, Marie-Agnès Bringer, Marisa Brini, Glauber C Brito, Bertha Brodin, Paul S Brookes, Eric J Brown, Karen Brown, Hal E Broxmeyer, Alain Bruhat, Patricia Chakur Brum, John H Brumell, Nicola Brunetti-Pierri, Robert J Bryson-Richardson, Shilpa Buch, Alastair M Buchan, Hikmet Budak, Dmitry V Bulavin, Scott J Bultman, Geert Bultynck, Vladimir Bumbasirevic, Yan Burelle, Robert E Burke, Margit Burmeister, Peter Bütikofer, Laura Caberlotto, Ken Cadwell, Monika Cahova, Dongsheng Cai, Jingjing Cai, Qian Cai, Sara Calatayud, Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) published pages: 1-222, ISSN: 1554-8627, DOI: 10.1080/15548627.2015.1100356 |
Autophagy 12/1 | 2019-05-03 |
2017 |
Inês B. Santarino, OtÃlia V. Vieira Maturation of phagosomes containing different erythrophagocytic particles in primary macrophages published pages: 1281-1290, ISSN: 2211-5463, DOI: 10.1002/2211-5463.12262 |
FEBS Open Bio 7/9 | 2019-05-03 |
2016 |
João Carlos Ribeiro, Bárbara Oliveiros, Paulo Pereira, Natália António, Thomas Hummel, António Paiva, Eduardo D. Silva Accelerated age-related olfactory decline among type 1 Usher patients published pages: , ISSN: 2045-2322, DOI: 10.1038/srep28309 |
Scientific Reports 6/1 | 2019-05-03 |
2017 |
Inês B. Santarino, Michelle S. Viegas, Neuza S. Domingues, Ana M. Ribeiro, Miguel P. Soares, OtÃlia V. Vieira Involvement of the p62/NRF2 signal transduction pathway on erythrophagocytosis published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-017-05687-1 |
Scientific Reports 7/1 | 2019-05-03 |
2017 |
Teresa M. Ribeiro-Rodrigues, Tiago L. Laundos, Rita Pereira-Carvalho, Daniela Batista-Almeida, Ricardo Pereira, Vanessa Coelho-Santos, Ana P. Silva, Rosa Fernandes, Monica Zuzarte, Francisco J. Enguita, Marina C. Costa, Perpetua Pinto-do-Ó, Marta T. Pinto, Pedro Gouveia, Lino Ferreira, Justin C. Mason, Paulo Pereira, Brenda R. Kwak, Diana S. Nascimento, Henrique Girão Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis published pages: 1338-1350, ISSN: 0008-6363, DOI: 10.1093/cvr/cvx118 |
Cardiovascular Research 113/11 | 2019-05-03 |
2017 |
Neuza Domingues, LuÃs M.B.B. Estronca, João Silva, Marisa R. Encarnação, Rita Mateus, Diogo Silva, Inês B. Santarino, Margarida Saraiva, Maria I.L. Soares, Teresa M.V.D. Pinho e Melo, António Jacinto, Winchil L.C. Vaz, OtÃlia V. Vieira Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages published pages: 210-220, ISSN: 1388-1981, DOI: 10.1016/j.bbalip.2016.10.009 |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1862/2 | 2019-05-03 |
2016 |
CecÃlia Seixas, Soo Young Choi, Noemi Polgar, Nicole L. Umberger, Michael P. East, Xiaofeng Zuo, Hugo Moreiras, Rania Ghossoub, Alexandre Benmerah, Richard A. Kahn, Ben Fogelgren, Tamara Caspary, Joshua H. Lipschutz, Duarte C. Barral Arl13b and the exocyst interact synergistically in ciliogenesis published pages: 308-320, ISSN: 1059-1524, DOI: 10.1091/mbc.E15-02-0061 |
Molecular Biology of the Cell 27/2 | 2019-05-03 |
2017 |
Jayne Louise Wilson, Frédéric Bouillaud, Ana S. Almeida, Helena L. Vieira, Mohand Ouidir Ouidja, Jean-Luc Dubois-Randé, Roberta Foresti, Roberto Motterlini Carbon monoxide reverses the metabolic adaptation of microglia cells to an inflammatory stimulus published pages: 311-323, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2017.01.022 |
Free Radical Biology and Medicine 104 | 2019-05-03 |
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Ana S. Almeida, Ursula Sonnewald, Paula M. Alves, Helena L.A. Vieira Carbon monoxide improves neuronal differentiation and yield by increasing the functioning and number of mitochondria published pages: 423-435, ISSN: 0022-3042, DOI: 10.1111/jnc.13653 |
Journal of Neurochemistry 138/3 | 2019-05-03 |
2015 |
Tania Martins-Marques, Teresa Ribeiro-Rodrigues, Paulo Pereira, Patrice Codogno, Henrique Girao Autophagy and Ubiquitination in Cardiovascular Diseases published pages: 243-251, ISSN: 1044-5498, DOI: 10.1089/dna.2014.2765 |
DNA and Cell Biology 34/4 | 2019-05-03 |
2015 |
Joao Vasco Ferreira, Ana Rosa Soares, Jose Silva Ramalho, Paulo Pereira, Henrique Girao K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy published pages: , ISSN: 2045-2322, DOI: 10.1038/srep10210 |
Scientific Reports 5/1 | 2019-05-03 |
2015 |
Teresa M. Ribeiro-Rodrigues, Steve Catarino, Maria J. Pinho, Paulo Pereira, Henrique Girao Connexin 43 ubiquitination determines the fate of gap junctions: restrict to survive published pages: , ISSN: 0300-5127, DOI: |
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João T. Proença, Duarte C. Barral, Isabel Gordo Commensal-to-pathogen transition: One-single transposon insertion results in two pathoadaptive traits in Escherichia coli -macrophage interaction published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-017-04081-1 |
Scientific Reports 7/1 | 2019-05-03 |
2017 |
Margaret Alexander, Andrew G. Ramstead, Kaylyn M. Bauer, Soh-Hyun Lee, Marah C. Runtsch, Jared Wallace, Thomas B. Huffaker, Dane K. Larsen, Tanya Tolmachova, Miguel C. Seabra, June L. Round, Diane M. Ward, Ryan M. O’Connell Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli published pages: 3559-3570, ISSN: 0022-1767, DOI: 10.4049/jimmunol.1700904 |
The Journal of Immunology 199/10 | 2019-05-03 |
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Susana S. Lopes, Martin Distel, Claudia Linker, Rita Fior, Rui Monteiro, Isaac H. Bianco, Ruben Portugues, Uwe Strähle, Leonor Saúde Report of the 4th European Zebrafish Principal Investigator Meeting published pages: 590-595, ISSN: 1545-8547, DOI: 10.1089/zeb.2016.1364 |
Zebrafish 13/6 | 2019-05-03 |
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Biochemical Journal 467/2 | 2019-05-03 |
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Biology Open 4/11 | 2019-05-03 |
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T. D. Montenegro-Johnson, D. I. Baker, D. J. Smith, S. S. Lopes Three-dimensional flow in Kupffer’s Vesicle published pages: 705-725, ISSN: 0303-6812, DOI: 10.1007/s00285-016-0967-7 |
Journal of Mathematical Biology 73/3 | 2019-05-03 |
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Ana S. Almeida, Helena L. A. Vieira Role of Cell Metabolism and Mitochondrial Function During Adult Neurogenesis published pages: 1787-1794, ISSN: 0364-3190, DOI: 10.1007/s11064-016-2150-3 |
Neurochemical Research 42/6 | 2019-05-03 |
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Ana Silva, Luana Naia, Alejandro Dominguez, Márcio Ribeiro, Joana Rodrigues, OtÃlia V. Vieira, Volkmar Lessmann, Ana Cristina Rego Overexpression of BDNF and Full-Length TrkB Receptor Ameliorate Striatal Neural Survival in Huntington\'s Disease published pages: 207-218, ISSN: 1660-2854, DOI: 10.1159/000375447 |
Neurodegenerative Diseases 15/4 | 2019-05-03 |
2015 |
Ana Rosa Soares, Tania Martins-Marques, Teresa Ribeiro-Rodrigues, Joao Vasco Ferreira, Steve Catarino, Maria João Pinho, Monica Zuzarte, Sandra Isabel Anjo, Bruno Manadas, Joost P.G. Sluijter, Paulo Pereira, Henrique Girao Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells published pages: , ISSN: 2045-2322, DOI: 10.1038/srep13243 |
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Annual Review of Fluid Mechanics | 2019-02-12 |
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