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ACDC SIGNED

Artificial Cells with Distributed Cores to Decipher Protein Function

Total Cost €

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EC-Contrib. €

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Partnership

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 ACDC project word cloud

Explore the words cloud of the ACDC project. It provides you a very rough idea of what is the project "ACDC" about.

integration    living    explore    job    cells    intellectual    metabolism    interdisciplinary       union    microfluidics    demand    academia    toward    hierarchical    medicine    microwave    assembled    cellular    liquid    reconfigurable    environments    team    architectures    disease    artificial    configurable    apps    outreach    class    threat    supramolecular    theranostics    international    compartmental    membrane    expression    sensing    economic    ethical    enterprise    creation    framework    bio    chip    dna    vitro    heavily    wetware    public    re    organelles    platform    cell    acdc    start    collective    commercial    channels    embodiment    technological    microscale    integrating    compartmentalisation    envision    exemplars    communication    precision    diverse    chemical    actuation    translation    nontrivial    building    vision    health    technologies    core    functional    bioremediation    industry    valuable    programmable    advantage    miniaturization    assembly    secondary    55    personalized    resonators    gene    performance    finds    lab    constructs    engagement    first    mathematical    inter    cores    dimensions    workplan    compounds    property    construct    responsive    tissues    generation    recapitulates    concentrating    detection    bioagent    sectors    mobile   

Project "ACDC" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI TRENTO 

Organization address
address: VIA CALEPINA 14
city: TRENTO
postcode: 38122
website: www.unitn.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 4˙376˙295 €
 EC max contribution 4˙376˙295 € (100%)
 Programme 1. H2020-EU.1.2.2. (FET Proactive)
 Code Call H2020-FETPROACT-2018-01
 Funding Scheme RIA
 Starting year 2019
 Duration (year-month-day) from 2019-01-01   to  2023-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI TRENTO IT (TRENTO) coordinator 1˙198˙437.00
2    CARDIFF UNIVERSITY UK (CARDIFF) participant 1˙144˙596.00
3    EXPLORA SRL IT (ROMA) participant 729˙500.00
4    ZURCHER HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN CH (WINTERTHUR) participant 630˙550.00
5    ELVESYS FR (PARIS) participant 512˙125.00
6    MUSEO DELLE SCIENZE IT (TRENTO) participant 161˙086.00

Map

 Project objective

We envision a future where ‘chemical apps’ on mobile devices produce on demand valuable compounds for health and performance as well as apps for bioagent threat detection and disease. To take concrete and defined steps toward this future vision, we will exploit the miniaturization provided by lab on a chip technology and construct responsive architectures and metabolism based on living cells and tissues. We will build programmable and re-configurable, (bio)chemical processes, with precision, order, and as hierarchical cellular constructs, in the same way as living systems. We will enable microscale, liquid-based, chemical compartmentalisation (cores), and inter-compartmental (core-core) communication, just as one finds in organelles, cells and tissues. ACDC will focus on developing this next generation technology through a detailed workplan that heavily involves the nontrivial tasks of integrating diverse state of the art technologies including microfluidics, microwave resonators, DNA-based supramolecular assembly, in vitro gene expression and the integration of membrane channels into a functional platform. In a future embodiment of this project, artificial cell technology will be used as programmable and reconfigurable matter for specific applications, including theranostics and personalized medicine as well as sensing and actuation in the environments for bioremediation. As the first steps towards that future vision, we aim to produce an artificial technological construct and process that recapitulates some aspects of living systems on the microscale, and therefore this project will produce exemplars of secondary living technologies concentrating on the wetware class [1] but also a multi-level mathematical framework. We have assembled an international, interdisciplinary team from academia, industry and public engagement. Our outreach and engagement programme will define the impact in both the public and economic sectors with ethical dimensions considered. Further, building upon 55 years of collective start-up enterprise experience, we will explore the translation of new intellectual property generated into commercial advantage and job creation for the European Union.

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The information about "ACDC" are provided by the European Opendata Portal: CORDIS opendata.

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