Opendata, web and dolomites

LINCE SIGNED

Light INduced Cell control by Exogenous organic semiconductors

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 LINCE project word cloud

Explore the words cloud of the LINCE project. It provides you a very rough idea of what is the project "LINCE" about.

neuroscience    visible    biocompatibility    stimuli    cells    reported    device    biological    regulation    candidates    ionic    optical    modulates    sustain    tools    reversibility    efficacy    pathological    drugs    majority    selectivity    regeneration    stem    physiology    easily    bear    first    biomolecules    astrocytes    sensitivity    modulation    light    box    animal    thermal    vitro    excitation    investigations    invasiveness    differentiation    respect    conduction    standard    temporal    chemical    medical    lower    achievable    search    unprecedented    regenerative    nervous    electronic    materials    sensitive    tissue    mediated    provides    central    semiconductors    vast    medicine    disorders    ideal    vivo    understand    tool    doctors    technologies    polymer    electrical    yield    timeless    optically    organic    hot    active    behavior    neuroscientists    functionalized    resolution    mission    combination    dysfunctions    inherently    combine    os    regulate    spatio    fundamental    nir    possibility    lince    living    neuronal    extremely    biocompatible    significantly    flexible    cell    specificity    functions    broaden    relevance   

Project "LINCE" data sheet

The following table provides information about the project.

Coordinator
FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA 

Organization address
address: VIA MOREGO 30
city: GENOVA
postcode: 16163
website: www.iit.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 1˙866˙250 €
 EC max contribution 1˙866˙250 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-STG
 Funding Scheme ERC-STG
 Starting year 2019
 Duration (year-month-day) from 2019-03-01   to  2024-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA IT (GENOVA) coordinator 1˙866˙250.00

Map

 Project objective

LINCE will develop light-sensitive devices based on organic semiconductors (OS) for optical regulation of living cells functions. The possibility to control the activity of biological systems is a timeless mission for neuroscientists, since it allows both to understand specific functions and to manage dysfunctions. Optical modulation provides, respect to traditional electrical methods, unprecedented spatio-temporal resolution, lower invasiveness, and higher selectivity. However, the vast majority of animal cells does not bear specific sensitivity to light. Search for new materials capable to optically regulate cell activity is thus an extremely hot topic. OS are ideal candidates, since they are inherently sensitive to visible light and highly biocompatible, sustain both ionic and electronic conduction, can be functionalized with biomolecules and drugs. Recently, it was reported that polymer-mediated optical excitation efficiently modulates the neuronal electrical activity. LINCE will significantly broaden the application of OS to address key, open issues of high biological relevance, in both neuroscience and regenerative medicine. In particular, it will develop new devices for: (i) regulation of astrocytes functions, active in many fundamental processes of the central nervous system and in pathological disorders; (ii) control of stem cell differentiation and tissue regeneration; (iii) control of animal behavior, to first assess device biocompatibility and efficacy in vivo. LINCE tools will be sensitive to visible and NIR light, flexible, biocompatible, and easily integrated with any standard physiology set-up. They will combine electrical, chemical and thermal stimuli, offering high spatio-temporal resolution, reversibility, specificity and yield. The combination of all these features is not achievable by current technologies. Overall, LINCE will provide neuroscientists and medical doctors with an unprecedented tool-box for in vitro and in vivo investigations.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "LINCE" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "LINCE" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

KineTic (2020)

New Reagents for Quantifying the Routing and Kinetics of T-cell Activation

Read More  

CARBYNE (2020)

New carbon reactivity rules for molecular editing

Read More  

INSPIRE (2019)

System-wide discovery and analysis of inositol pyrophosphate signaling networks in plants

Read More