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cONCReTE SIGNED

DevelOpmeNt of Cancer RNA TherapEutics

Total Cost €

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EC-Contrib. €

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Partnership

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cONCReTE project word cloud

Explore the words cloud of the cONCReTE project. It provides you a very rough idea of what is the project "cONCReTE" about.

regulate novels concert therapies functional vivo identification quality cancer expression applicability staff molecular biological ing personalized clinical academic scientists sme form governing genes exchange ideal inhibiting ncrna exposed imaging inter accumulation potentially platform aptamers experts epigenetics monitor safe environments animal business cell biology interdisciplinary tumor life non skills patients appropriately drug designed transduction types progression members efficacy tumors teams tools synergetic formulation delivering sectoral models reveal oncology appropriate links joint toxic derivatives stable malignant complementary codingrnas contribution network competitiveness education training performed signal innovative international spreading oncogenic molecules qol class classes cargoes cells therapeutic ncrnas

Project "cONCReTE" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II Organization address address: CORSO UMBERTO I, 40 city: NAPOLI postcode: 80138 website: www.unina.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Italy [IT]
Total cost	2˙060˙800 €
EC max contribution	2˙060˙800 € (100%)
Programme	1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
Code Call	H2020-MSCA-RISE-2019
Funding Scheme	MSCA-RISE
Starting year	2020
Duration (year-month-day)	from 2020-05-01 to 2024-04-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II Organization address address: CORSO UMBERTO I, 40 city: NAPOLI postcode: 80138 website: www.unina.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (NAPOLI)	coordinator	165˙600.00
2	PERCUROS BV PERCUROS BV Organization address address: PLESMANLAAN 1 city: LEIDEN postcode: 2333 BZ website: www.percuros.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (LEIDEN)	participant	174˙800.00
3	JENACELL GMBH JENACELL GMBH Organization address address: GOSCHWITZER STR. 22 city: JENA postcode: 7745 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (JENA)	participant	128˙800.00
4	ASSOCIAZIONE HAND IN HAND ASSOCIAZIONE HAND IN HAND Organization address address: PIAZZA ROMA 2 city: NEMI postcode: 74 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (NEMI)	participant	124˙200.00
5	CLINICA MEDITERRANEA SPA CLINICA MEDITERRANEA SPA Organization address address: VIA ORAZIO 2 city: NAPOLI postcode: 80122 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (NAPOLI)	participant	124˙200.00
6	TACIT BIO INNOVATION LIMITED TACIT BIO INNOVATION LIMITED Organization address address: BENNETT CORNER HOUSE, 33 COLESHILL STREET city: SUTTON COLDFIELD postcode: B72 1SD website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (SUTTON COLDFIELD)	participant	119˙600.00
7	TECOBIOSCIENCES GMBH TECOBIOSCIENCES GMBH Organization address address: HABICHTSTRASSE 21 city: LANDSHUT postcode: 84036 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (LANDSHUT)	participant	119˙600.00
8	CONSIGLIO NAZIONALE DELLE RICERCHE CONSIGLIO NAZIONALE DELLE RICERCHE Organization address address: PIAZZALE ALDO MORO 7 city: ROMA postcode: 185 website: www.cnr.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (ROMA)	participant	110˙400.00
9	ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Organization address address: DR MOLEWATERPLEIN 40 city: ROTTERDAM postcode: 3015 GD website: www.erasmusmc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ROTTERDAM)	participant	110˙400.00
10	FUNDACIO INSTITUT DE RECERCA CONTRA LA LEUCEMIA JOSEP CARRERAS FUNDACIO INSTITUT DE RECERCA CONTRA LA LEUCEMIA JOSEP CARRERAS Organization address address: CARRER MUNTANER 383 3/2 city: BARCELONA postcode: 8021 website: www.carrerasresearch.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARCELONA)	participant	110˙400.00
11	FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA Organization address address: AVENIDA DE PIO XII 55 city: PAMPLONA postcode: 31008 website: www.cima.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (PAMPLONA)	participant	110˙400.00
12	LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN Organization address address: GESCHWISTER SCHOLL PLATZ 1 city: MUENCHEN postcode: 80539 website: www.uni-muenchen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUENCHEN)	participant	110˙400.00
13	PROGREDUM GMBH PROGREDUM GMBH Organization address address: OTTERBERGER STRASSE 73 city: KAISERSLAUTERN postcode: 67659 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (KAISERSLAUTERN)	participant	110˙400.00
14	RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN Organization address address: REGINA PACIS WEG 3 city: BONN postcode: 53113 website: www.uni-bonn.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BONN)	participant	110˙400.00
15	UNIVERSITAET INNSBRUCK UNIVERSITAET INNSBRUCK Organization address address: INNRAIN 52 city: INNSBRUCK postcode: 6020 website: http://www.uibk.ac.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (INNSBRUCK)	participant	110˙400.00
16	UNIVERSITATEA DE MEDICINA SI FARMACIE IULIU HATIEGANU CLUJ-NAPOCA UNIVERSITATEA DE MEDICINA SI FARMACIE IULIU HATIEGANU CLUJ-NAPOCA Organization address address: VICTOR BABES STREET 8 city: Cluj-Napoca postcode: 400012 website: www.umfcluj.ro contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	RO (Cluj-Napoca)	participant	110˙400.00
17	XENOPAT SL XENOPAT SL Organization address address: CALLE FEIXA LLARGA S/N EDIFICI BIOINCUOADORA city: HOSPITALET DE LLOBREGAT postcode: 8907 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (HOSPITALET DE LLOBREGAT)	participant	110˙400.00

Map

Project objective

Non-codingRNAs (ncRNAs) represent a large class of molecules that in concert regulate the expression of genes involved in the key pathways governing cancer development and progression. They represent ideal targets for personalized cancer therapies and if appropriately designed they can provide specific, non-toxic and effective therapeutic tools. The identification of novel therapeutic ncRNAs and the design of their appropriate formulation is a key aspect for their clinical applicability. RISE- cONCReTE aims to form an international and inter-sectoral network of organizations working on a joint research programme on the development of a safe ncRNA-based drug. RISE- cONCReTE teams up experts in the fields of Molecular Oncology, Epigenetics, Signal transduction, Animal models, Therapeutic delivery and Imaging, business, and education. The participants will exchange skills, knowledge and staff members that will be exposed to synergetic and complementary research environments. RISE- cONCReTE will undertake an integrated approach to reveal novels functional links between ncRNAs and oncogenic pathways. We will: a) characterize novel classes of tumor-associated ncRNAs; b) investigate the impact of ncRNAs on key aspects of tumor cell biology; c) develop cargoes (e.g. aptamers) for delivering therapeutic ncRNA derivatives into specific cancer cell types. By using innovative in vivo imaging tools, we will monitor the accumulation of target ncRNAs in cancer cells and evaluate their biological efficacy in inhibiting the growth and spreading of malignant tumors. The resulting approaches will provide stable and effective tools thus potentially improving the quality of life (QOL) of the cancer patients. Further, the joint research and training programme of RISE- cONCReTE will be performed in academic institutions and SME to provide a unique interdisciplinary platform for scientists with a significant contribution to EU competitiveness.

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