ISOLATE
Developing single cell technologies for systems biology
| Coordinatore | GOETEBORGS UNIVERSITET
Organization address
address: VASAPARKEN contact info |
| Nazionalità Coordinatore | Sweden [SE] |
| Totale costo | 2˙994˙929 € |
| EC contributo | 2˙994˙929 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-2011-ITN |
| Funding Scheme | MC-ITN |
| Anno di inizio | 2012 |
| Periodo (anno-mese-giorno) | 2012-01-01 - 2015-12-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
GOETEBORGS UNIVERSITET
Organization address
address: VASAPARKEN contact info |
SE (GOETEBORG) | coordinator | 1˙021˙134.00 |
| 2 |
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZURICH
Organization address
address: Raemistrasse 101 contact info |
CH (ZUERICH) | participant | 493˙960.00 |
| 3 |
RIJKSUNIVERSITEIT GRONINGEN
Organization address
address: Broerstraat 5 contact info |
NL (GRONINGEN) | participant | 492˙065.00 |
| 4 |
SYDDANSK UNIVERSITET
Organization address
address: CAMPUSVEJ 55 contact info |
DK (ODENSE M) | participant | 290˙246.00 |
| 5 |
KINASEDETECT APS
Organization address
address: STATIONSVEJ 80 contact info |
DK (ARSLEV) | participant | 256˙050.00 |
| 6 |
UNIVERSITY OF YORK
Organization address
address: HESLINGTON contact info |
UK (YORK NORTH YORKSHIRE) | participant | 196˙229.02 |
| 7 |
LABORATORY IMAGING SPOL SRO
Organization address
address: NA PASECE 201/3 contact info |
CZ (PRAHA) | participant | 180˙275.00 |
| 8 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Organization address
address: University Offices, Wellington Square contact info |
UK (OXFORD) | participant | 64˙970.00 |
Mappa
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Obiettivo del progetto (Objective)
'Biological cells are entities with highly complex, non-linear control circuits. They can thus express intricate behavior, such as stochasticity-induced multistability, oscillations, responses at different time scales, hysteretic behavior, memory, etc. Biology is only about to start to investigate these phenomena, which all occur at single cell level and often result in phenotypic heterogeneity. It is required to experimentally probe single cells, as population-level analyses will mask most of the behaviors of individual cells. Development of single cell measurement techniques represents an area for exciting research and development, being the key enabling technique to ultimately understand important complex biological behaviors. The education of highly qualified specialists with multidisciplinary skills is a pivotal prerequisite for addressing these biological problems and, even more importantly, for transferring this knowledge into marketable products. This proposal seeks funding for a truly interdisciplinary European consortium to train researchers to develop and exploit novel technologies for single-cell analysis in the context of system-level metabolic cell behavior. The crucial importance of single cell analysis has been stressed in a recent Science News Focus and the area of metabolism was highlighted in Nature’s “New year, new science' outlook for 2011. ISOLATE represents an Initial Training Network involving eleven trainees. A range of methodologies will be included to provide unique training to fellows in single cell analyses and to investigate complex phenomena. A high degree of multidisciplinarity and the inclusion of key industrial stakeholders make ISOLATE especially suitable for a training program ranging from forefront microtechnology, bioengineering, biophysics, via analytical chemistry to biochemistry and systems biology.'