Coordinatore | SERVICIO MADRILENO DE SALUD
Organization address
address: PLAZA CARLOS TRIAS BERTRAN 7 contact info |
Nazionalità Coordinatore | Spain [ES] |
Sito del progetto | http://www.midfrail-study.org/ |
Totale costo | 7˙626˙484 € |
EC contributo | 5˙975˙821 € |
Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
Code Call | FP7-HEALTH-2011-two-stage |
Funding Scheme | CP-FP |
Anno di inizio | 2012 |
Periodo (anno-mese-giorno) | 2012-03-01 - 2016-02-29 |
# | ||||
---|---|---|---|---|
1 |
SERVICIO MADRILENO DE SALUD
Organization address
address: PLAZA CARLOS TRIAS BERTRAN 7 contact info |
ES (MADRID) | coordinator | 1˙325˙523.00 |
2 |
NICHE SCIENCE & TECHNOLOGY LTD
Organization address
address: WOLSEY DRIVE 96 contact info |
UK (KINGSTON UPON THAMES) | participant | 647˙542.30 |
3 |
CARDIFF UNIVERSITY
Organization address
address: Newport Road 30-36 contact info |
UK (CARDIFF) | participant | 492˙000.00 |
4 |
DIABETES FRAIL LIMITED
Organization address
address: OAKMOORE COURT 11 C KINGSWOOD ROAD HAPMTON LOVETT contact info |
UK (DROITWITCH) | participant | 350˙173.80 |
5 |
Nome Ente NON disponibile
Organization address
address: VIALE BENEDUCE 10 contact info |
IT (CASERTA) | participant | 336˙400.00 |
6 |
IGEN BIOTECH SL
Organization address
address: CALLE GUSTAVO FERNANDEZ BALVUENA 11 contact info |
ES (MADRID) | participant | 331˙200.00 |
7 |
UNIVERSITEIT GENT
Organization address
address: SINT PIETERSNIEUWSTRAAT 25 contact info |
BE (GENT) | participant | 327˙600.00 |
8 |
CHU HOPITAUX DE BORDEAUX
Organization address
address: RUE DUBERNAT 12 contact info |
FR (TALENCE) | participant | 314˙385.20 |
9 |
CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE
Organization address
address: "Rue Viguerie, Hotel-Dieu Saint Jacques 2" contact info |
FR (TOULOUSE) | participant | 308˙125.00 |
10 |
UNIVERSITY OF BEDFORDSHIRE
Organization address
address: PARK SQUARE contact info |
UK (LUTON) | participant | 291˙626.20 |
11 |
UNIVERSITAET ULM
Organization address
address: HELMHOLTZSTRASSE 16 contact info |
DE (ULM) | participant | 277˙440.00 |
12 |
UNIVERSITA CATTOLICA DEL SACRO CUORE
Organization address
address: Largo Agostino Gemelli 1 contact info |
IT (MILANO) | participant | 225˙600.00 |
13 |
UNIVERSIDAD DE CASTILLA - LA MANCHA
Organization address
address: CALLE ALTAGRACIA 50 contact info |
ES (CIUDAD REAL) | participant | 216˙800.00 |
14 |
VRIJE UNIVERSITEIT BRUSSEL
Organization address
address: PLEINLAAN 2 contact info |
BE (BRUSSEL) | participant | 204˙480.00 |
15 |
HEXABIO SARL
Organization address
address: AVENUE PASTEUR 286 contact info |
FR (PESSAC) | participant | 162˙400.00 |
16 |
UNIVERZITA KARLOVA V PRAZE
Organization address
address: Ovocny trh 5 contact info |
CZ (PRAHA 1) | participant | 149˙840.00 |
17 |
CONSORCIO DE APOYO A LA INVESTIGACION BIOMEDICA EN RED
Organization address
address: CALLE SINESIO DELGADO 6 contact info |
ES (MADRID) | participant | 14˙685.50 |
Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.
'The prevalence of diabetes in people ≥ 65 years approaches 25% (40% of all patients with diabetes are > 65 years). This number will increase 4-fold in people > 70 years in 2050. Diabetes results in a high personal and social health burden, and a significant public health burden in terms of rising healthcare costs. Diabetes is associated with increased functional decline in older people and may explain up to 20% of their excess risk of disability. Our project focuses on the use of interventions to improve functional status and enhance quality of life. This is justified because there has been a lack of intervention studies in this population and improvements in function and well-being may be of more clinical benefit in older patients than attention to metabolic control alone. The MID-FRAIL STUDY is a Phase IIb open randomized clinical trial to evaluate the effectiveness of a multi-modal intervention (optimizing medical management, resistance-based exercise program and educational/nutritional intervention) in 1,704 frail or pre-frail subjects ≥ 70 years with T2D to prevent functional decline and maintain or improve quality of life and its associated costs. This approach is original (both the intervention and outcomes are unique for studies in diabetes), relevant (it concerns 25% of people with diabetes), pertinent and feasible. The project is highly aligned with objectives pursued by two topics of this call: investigator-driven clinical trials in elderly populations (HEALTH 2011 2.2.2-1) and in diabetes complications (HEALTH.2011.2.4.3-1). The study aims to demonstrate a reduction of 20% in that risk, which will mean an annual prevention of around 700,000 incident cases of some disability in old people, with a major impact on global quality of life and financial costs. This is especially true in older women. Three research-intensive SMEs will play a leading role in this project and it also has the support of Diabetes UK, a major patient and family advocacy organisation'
In older people, diabetes is associated with increased frailty and functional decline. A new study focuses on interventions to improve quality of life by acting on the mechanisms involved in progression to functional decline.
Mechanisms of prevention of type 2 diabetes by lifestyle intervention in subjects with pre-diabetes or at high-risk for progression
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