VECTORIE

Vector-borne Risks for Europe: Risk assessment and control of West Nile and Chikungunya virus (VECTORIE)

Coordinatore	ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM    more  Organization address address: 's Gravendijkwal 230 city: ROTTERDAM postcode: 3015CE contact info Titolo: Mr. Nome: Wim Cognome: Leep Email: send email Telefono: +31 10 704 34 51 Fax: +31 10 704 47 60
Nazionalità Coordinatore	Netherlands [NL]
Sito del progetto	http://vectorie.eu/
Totale costo	3˙791˙100 €
EC contributo	2˙784˙402 €
Programma	FP7-HEALTH Specific Programme "Cooperation": Health
Code Call	FP7-HEALTH-2010-single-stage
Funding Scheme	CP-FP
Anno di inizio	2010
Periodo (anno-mese-giorno)	2010-11-01   -   2014-01-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM  Organization address address: 's Gravendijkwal 230 city: ROTTERDAM postcode: 3015CE contact info Titolo: Mr. Nome: Wim Cognome: Leep Email: send email Telefono: +31 10 704 34 51 Fax: +31 10 704 47 60	NL (ROTTERDAM)	coordinator	691˙400.00
2	WAGENINGEN UNIVERSITY  Organization address address: DROEVENDAALSESTEEG 4 city: WAGENINGEN postcode: 6708 PB contact info Titolo: Mr. Nome: Rudie Cognome: Jullens Email: send email Telefono: +31 317 485829 Fax: +31 317 483457	NL (WAGENINGEN)	participant	562˙180.00
3	LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN  Organization address address: GESCHWISTER SCHOLL PLATZ 1 city: MUENCHEN postcode: 80539 contact info Titolo: Prof. Nome: Gerd Cognome: Sutter Email: send email Telefono: +49 89 2180 2610 Fax: +49 89 2180 99 2610	DE (MUENCHEN)	participant	459˙900.00
4	UNIVERSITE D'AIX MARSEILLE  Organization address address: Boulevard Charles Livon 58 city: Marseille postcode: 13284 contact info Titolo: Ms. Nome: Céline Cognome: Damon Email: send email Telefono: +33 4 91 31 97 97 Fax: +33 6 98 87 72 76	FR (Marseille)	participant	304˙500.00
5	LATVIJAS BIOMEDICINAS PETIJUMU UN STUDIJU CENTRS  Organization address address: RATSUPITES IELA 1 city: RIGA postcode: 1067 contact info Nome: Lilita Cognome: Kundzina Email: send email Telefono: +371 67808204 Fax: +371 67442407	LV (RIGA)	participant	242˙844.75
6	INSTITUT PASTEUR  Organization address address: RUE DU DOCTEUR ROUX 25-28 city: PARIS CEDEX 15 postcode: 75724 contact info Titolo: Dr. Nome: Nadia Cognome: Khelef Email: send email Telefono: +33 1 40 61 33 78 Fax: +33 1 40 61 39 40	FR (PARIS CEDEX 15)	participant	192˙022.00
7	CYTOS BIOTECHLOLOGY AG  Organization address address: "Waggistrasse, 25" city: ZURICH-SCHLIEREN postcode: 8952 contact info Titolo: Mr. Nome: Jakob Cognome: Schlapbach Email: send email Telefono: +41 44 733 4747 Fax: +41 44 733 4740	CH (ZURICH-SCHLIEREN)	participant	168˙155.25
8	SZENT ISTVAN UNIVERSITY  Organization address address: Pater Karoly utca 1 city: GODOLLO postcode: 2100 contact info Titolo: Mr. Nome: Imre Cognome: Tatár Email: send email Telefono: +36 28 522 000 Fax: +36 28 522 008	HU (GODOLLO)	participant	163˙400.00
9	UNIVERSITE DE LA MEDITERRANEE D'AIX-MARSEILLE II  Organization address address: Boulevard Charles Livon, Jardin du Pharo 58 city: MARSEILLE postcode: 13284 contact info Titolo: Ms. Nome: Céline Cognome: Damon Email: send email Telefono: +33 4 91 31 97 97 Fax: +33 6 98 87 72 76	FR (MARSEILLE)	participant	0.00

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 Obiettivo del progetto (Objective)

'VECTORIE provides for a multidisciplinary approach combining the expertise of (basic) virology, entomology and advanced vaccinology to monitor the spread of and diagnose, prevent and treat infections caused by West Nile virus (WNV) and Chikungunya virus (CHIKV). VECTORIE therefore addresses Europe’s need to prepare for these vector-borne diseases along three strands:

Vector biology: WNV and CHIKV are emerging mosquito-borne viral diseases. Generating novel knowledge on avian and mammalian host susceptibility and vector competence of the two main vectors of WNV and CHIKV, will lead to important insights necessary for determining the type of surveillance system appropriate for European countries to detect and predict emerging WNV and/or CHIKV outbreaks.

Virulence & pathogenesis: VECTORIE addresses the need for understanding how CHIKV and the four WNV lineages circulating in Europe differ in their capacity to cause neuroinvasive disease. These studies will improve Europe’s ability to monitor the spread of these infections and will lead to diagnostic and prognostic tools as well as novel intervention strategies.

Vaccination strategies: The severity of WNV and CHIKV neuroinvasive disease, the long term sequelae reported from infected individuals and the negative impact of these infections on the blood transfusion system collectively justify the development of safe and effective vaccines against these infections. VECTORIE brings together a platform of technologies using either virus-like particles or Modified vaccinia Ankara vaccine candidates, for the development of novel mono- and bivalent vaccine candidates against WNV and CHIKV.

VECTORIE’s integrated approach will largely contribute to adequate risk assessment and risk mitigation of the emerging health threat caused by WNV and CHIKV infections in Europe.'