PHARMASEA
Increasing Value and Flow in the Marine Biodiscovery Pipeline
| Coordinatore | KATHOLIEKE UNIVERSITEIT LEUVEN
Organization address
address: Oude Markt 13 contact info |
| Nazionalità Coordinatore | Belgium [BE] |
| Totale costo | 13˙289˙395 € |
| EC contributo | 9˙465˙907 € |
| Programma | FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology |
| Code Call | FP7-KBBE-2012-6-singlestage |
| Funding Scheme | CP-TP |
| Anno di inizio | 2012 |
| Periodo (anno-mese-giorno) | 2012-10-01 - 2016-09-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
KATHOLIEKE UNIVERSITEIT LEUVEN
Organization address
address: Oude Markt 13 contact info |
BE (LEUVEN) | coordinator | 1˙119˙976.00 |
| 2 |
FUNDACION CENTRO DE EXCELENCIA EN INVESTIGACION DE MEDICAMENTOS INNOVADORES EN ANDALUCIA
Organization address
address: AVDA DEL CONOCIMIENTO 3 contact info |
ES (ARMILLA GRANADA) | participant | 818˙294.00 |
| 3 |
THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN
Organization address
address: KING'S COLLEGE REGENT WALK contact info |
UK (ABERDEEN) | participant | 753˙273.00 |
| 4 |
UNIVERSITETET I TROMSOE
Organization address
address: Hansine Hansens veg 14 contact info |
NO (TROMSO) | participant | 746˙667.00 |
| 5 |
SEALIFE PHARMA GMBH
Organization address
address: TECHNOPARK 1 GEB B EG contact info |
AT (TULLN) | participant | 624˙815.00 |
| 6 |
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
Organization address
address: "PAZO DE SAN XEROME, PRAZA DO OBRADOIRO S/N" contact info |
ES (SANTIAGO DE COMPOSTELA) | participant | 612˙176.00 |
| 7 |
ECOAST RESEARCH CENTRE OSTEND BVBA
Organization address
address: POLDERSTRAAT 3 contact info |
BE (DAMME) | participant | 524˙911.00 |
| 8 |
DANMARKS TEKNISKE UNIVERSITET
Organization address
address: Anker Engelundsvej 1, Building 101A contact info |
DK (KONGENS LYNGBY) | participant | 442˙212.00 |
| 9 |
ADVANCED CHEMISTRY DEVELOPMENT UK LIMITED
Organization address
address: NEW STREET SQUARE 5 contact info |
UK (LONDON) | participant | 442˙090.00 |
| 10 |
CONSIGLIO NAZIONALE DELLE RICERCHE
Organization address
address: Piazzale Aldo Moro 7 contact info |
IT (ROMA) | participant | 429˙266.00 |
| 11 |
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK
Organization address
address: Western Road contact info |
IE (CORK) | participant | 418˙152.00 |
| 12 |
STAZIONE ZOOLOGICA ANTON DOHRN
Organization address
address: Villa Comunale contact info |
IT (NAPOLI) | participant | 409˙022.00 |
| 13 |
DEEP TEK LIMITED
Organization address
address: KILBURNS contact info |
UK (NEWPORT ON TAY) | participant | 389˙286.00 |
| 14 |
C-LECTA GMBH
Organization address
address: Deutscher Platz 5b contact info |
DE (Leipzig) | participant | 302˙947.00 |
| 15 |
BIOCOM
Organization address
address: LUTZOWSTRASSE 33-36 contact info |
DE (BERLIN) | participant | 268˙815.00 |
| 16 |
THE ROYAL SOCIETY OF CHEMISTRY
Organization address
address: Milton Road - Thomas Graham House - Science Park contact info |
UK (CAMBRIDGE) | participant | 245˙039.00 |
| 17 |
"Institute of Microbiology, Chinese Academy of Sciences"
Organization address
address: West Beichen Road 1 contact info |
CN (Beijing) | participant | 148˙508.00 |
| 18 |
ASOCIACION INSTITUTO NACIONAL DE BIODIVERSIDAD
Organization address
address: "400 M. NORTE, 300 M. OESTE DEL CEMENTERIO" contact info |
CR (SANTO DOMINGO DE HEREDIA) | participant | 148˙508.00 |
| 19 |
Instituto de Dinamica Celular y Biotecnologia
Organization address
address: CALLE BEAUCHEF 850 contact info |
CL (SANTIAGO) | participant | 148˙508.00 |
| 20 |
UNIVERSITY OF THE WESTERN CAPE
Organization address
address: MODDERDAMM ROAD contact info |
ZA (BELLVILLE) | participant | 148˙508.00 |
| 21 |
WUHAN UNIVERSITY
Organization address
address: LUOJIA HILL contact info |
CN (WUHAN) | participant | 148˙508.00 |
| 22 |
BIOBRIDGE LIMITED
Organization address
address: ST. BARNABAS ROAD 45 contact info |
UK (CAMBRIDGE) | participant | 116˙699.00 |
| 23 |
UNION INTERNATIONALE POUR LA CONSERVATION DE LA NATURE ET DE SES RESSOURCES
Organization address
address: RUE MAUVERNEY 28 contact info |
CH (GLAND) | participant | 59˙727.00 |
| 24 |
AQUAPHARM BIODISCOVERY LIMITED
Organization address
address: Glenfinlas Street contact info |
UK (EDINBURGH) | participant | 0.00 |
| 25 |
UNIVERSITY OF WAIKATO
Organization address
address: HILLCREST ROAD BLOCK B contact info |
NZ (HAMILTON) | participant | 0.00 |
Mappa
Word cloud
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Obiettivo del progetto (Objective)
'The PharmaSea project focuses on obstacles in marine biodiscovery research, development and commercialization and brings together a broad interdisciplinary team of academic and industry researchers and specialists to address and overcome these. The partners are ideally placed to demonstrate how to widen the bottlenecks and increase the flow of ideas and products derived from the marine microbiome towards a greater number of successes in a larger number of application areas. Despite the tremendous potential of marine biodiscovery, exploitation, particularly at a commercial scale, has been hampered by a number of constraints. These relate to access (physical and legal), genetics of the organisms, compound isolation, structure elucidation, early reliable validation of biological activity and best mechanisms of flow-through into exploitation. PharmaSea will solve these chronic bottlenecks by developing essential actions beyond the state of the art and linking them with best practice and appropriate pragmatic approaches. The robust pipeline structure established within PharmaSea will process a wide genetic basis including marine microbial strain collections held by partners and new strain collections from extreme environments (deep, cold and hot vent habitats) to produce new products with desirable characteristics for development by the SME partners in three accessible market sectors, health (infection, inflammation, CNS diseases), personal care and nutrition. The global aim of PharmaSea is to produce two compounds at larger scale and advance them to pre-clinical evaluation. To address relevant challenges in marine biodiscovery related to policy and legal issues, PharmaSea will bring together practitioners, legal experts, policy advisors/makers and other stakeholders, focusing on the feasibility of harmonising, aligning and complementing current legal frameworks with recommendations and ready to use solutions tailored to marine biodiscovery.'
Introduzione (Teaser)
The world's oceans are home to more living organisms, especially microorganisms, than any other environment on the planet. However, successful exploitation of this exceptional resource has been limited, despite its enormous potential for harvesting unique biological compounds with benefits for all of humanity.
Descrizione progetto (Article)
The purpose of the project 'Increasing value and flow in the marine biodiscovery pipeline' (http://www.pharma-sea.eu/ (PHARMASEA)) is to discover new marine bacteria and novel compounds. In addition, the consortium will improve the effectiveness of the biodiscovery pipeline, thereby making bioresources attractive to industry.
Project partners will achieve their aim by processing genetic material from in-house collections of microbial strains, while seeking out new strains from extreme marine environments. These will be used to develop new products for the pharmaceutical, food and nutrition, and cosmetic sectors. The main disease areas to be addressed are microbial infection, diseases of the central nervous system and inflammation.
By sampling some of the deepest parts of the ocean floor, PHARMASEA hopes to utilise microorganisms that are new to science. Deep ocean trenches are 'islands of diversity' with a unique chemistry and where evolution may have developed differently. Because so little of this extreme environment has been explored, PHARMASEA is breaking new ground.
The final goal of this exciting initiative is to produce two compounds from newly discovered microorganisms on a large scale. These compounds will be taken forward to pre-clinical evaluation for treating infection or diseases of the central nervous system. Other outputs will include a validated model biodiscovery pipeline, new chemometric tools, data mining techniques and data sets.
Furthermore, PHARMASEA will develop solutions to improving access to marine bioresources in different habitats and jurisdictions, and equitable sharing of the benefits from their exploitation. A toolbox will also be created to navigate legal aspects in order to simplify and speed up the marine biodiscovery process.
PHARMASEA is not just expected to have a major impact on scientific progress, it will also influence policy and enhance economic performance. It will also strengthen the competiveness of the European Research Area (ERA) by increasing technological know-how through interdisciplinary and international cooperation, thereby contributing to Europe's knowledge-based economy.