Coordinatore | UNIVERSITEIT TWENTE
Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie. |
Nazionalità Coordinatore | Netherlands [NL] |
Totale costo | 1˙496˙400 € |
EC contributo | 1˙496˙400 € |
Programma | FP7-IDEAS-ERC
Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
Code Call | ERC-2012-StG_20111012 |
Funding Scheme | ERC-SG |
Anno di inizio | 2012 |
Periodo (anno-mese-giorno) | 2012-11-01 - 2017-10-31 |
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1 |
UNIVERSITEIT TWENTE
Organization address
address: DRIENERLOLAAN 5 contact info |
NL (ENSCHEDE) | hostInstitution | 1˙496˙400.00 |
2 |
UNIVERSITEIT TWENTE
Organization address
address: DRIENERLOLAAN 5 contact info |
NL (ENSCHEDE) | hostInstitution | 1˙496˙400.00 |
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'Supramolecular helices are a striking expression of chirality which is found at every level of biological materials, from plant cell walls to bones. Helical biomaterials formed out of equilibrium display multiple length scales, adaptation of structure to function and responsiveness to changing environments, a unique set of features that constitutes a fascinating source of inspiration for materials science. However, matching the complexity of these biological architectures by rational design of synthetic systems remains a major contemporary challenge. The aim of this project is to develop sophisticated helical materials with responsive architectures that are of interest in optical communication, energy management, photonic materials and mechanical actuation. The innovative and versatile approach proposed here consists in using light i) to engineer the period, handedness and orientation of the cholesteric helix, and ii) to stabilise the structures formed out of equilibrium by in-situ formation of polymer networks. Three tasks will run concurrently: Task 1: Stimuli-responsive infrared super-reflectors Task 2: Dynamic templates for long range ordering of nano-objects Task 3: Photomechanical actuation of helicoids and spiral ribbons “Phelix” will yield complex systems that reach beyond the state of the art in stimuli-responsive materials, push the frontiers of research on supramolecular helices and shed new light on transmission of chirality across length scales. Ultimately, the omnipresence of helical structures in nature means that biomedical applications could be envisioned also. The proposal builds on my recent investigations on light-responsive helices in cholesteric liquid crystals. I have demonstrated the expertise in liquid crystals, photochemistry and microscopy required for this research and my leadership experience ensures its success.'
The role of Tumour suppressor of lung cancer 1 (TSLC1) signalling in lung repair and cancer-associated epithelial-mesenchymal transitions (EMTs)
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