COSMIC
Community-based scheduled screening and treatment of malaria in pregnancy for improved maternal and infant health: a cluster-randomized trial
| Coordinatore | HET KONINKLIJK INSTITUUT VOOR DE TROPEN
Organization address
address: "Mauritskade, 63" contact info |
| Nazionalità Coordinatore | Netherlands [NL] |
| Sito del progetto | http://www.cosmicmalaria.eu/ |
| Totale costo | 3˙944˙701 € |
| EC contributo | 2˙997˙218 € |
| Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
| Code Call | FP7-HEALTH-2012-INNOVATION-1 |
| Funding Scheme | CP-FP |
| Anno di inizio | 2012 |
| Periodo (anno-mese-giorno) | 2012-09-01 - 2016-08-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
HET KONINKLIJK INSTITUUT VOOR DE TROPEN
Organization address
address: "Mauritskade, 63" contact info |
NL (AMSTERDAM) | coordinator | 468˙815.40 |
| 2 |
CENTRE MURAZ
Organization address
address: Avenue Mamadou Konate contact info |
BF (BOBO-DIOULASSO) | participant | 694˙719.00 |
| 3 |
MEDICAL RESEARCH COUNCIL
Organization address
address: NORTH STAR AVENUE POLARIS HOUSE contact info |
UK (SWINDON) | participant | 619˙592.00 |
| 4 |
Ministere de la sante
Organization address
address: n/a contact info |
BJ (Cotonou) | participant | 566˙998.00 |
| 5 |
PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE
Organization address
address: Nationalestraat 155 contact info |
BE (ANTWERPEN) | participant | 260˙360.40 |
| 6 |
IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE
Organization address
address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD contact info |
UK (LONDON) | participant | 199˙958.00 |
| 7 |
WORLD HEALTH ORGANIZATION.
Organization address
address: Avenue Appia 20 contact info |
CH (GENEVE) | participant | 186˙775.20 |
Mappa
Word cloud
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Obiettivo del progetto (Objective)
'Pregnant women are very susceptible to malaria infection and Malaria in Pregnancy (MiP) is a major cause of maternal anaemia and low birth weight (LBW) that leads to infant mortality, poor growth and development. In low transmission areas, malaria can become severe, resulting in maternal and foetal death. In sub-Saharan Africa (SSA) MiP is responsible for 8–14% of LBW, 3–8% of infant deaths, higher risk of post-partum haemorrhage and >10,000 maternal deaths/year. Prevention like, bed nets and intermittent preventive treatment with sulphadoxine-pyrimethamine (IPTp/SP), is cheap and cost-effective, but coverage achieved by these interventions is low. Therefore, we propose Community Health Workers (CHW) to implement scheduled intermittent screening at community level with RDT of pregnant women and if positive treat with anti-malarials (SST). In addition CHWs will encourage pregnant women to attend antenatal clinics (ANC) for other pregnancy-targeted interventions and IPTp/SP, thereby improving its coverage. This approach combines existing IPTp/SP with SST at village level as an extension of Home based management of malaria (HMM). This low cost (based on existing practice) and simple (diagnosis by RDTs) intervention improves maternal and newborn health and capitalise on an already existing intervention (HMM). The aim of this proposal is to determine the added value (as compared to IPTp/SP alone implemented in health facilities) of community SST of pregnant women implemented through the CHW involved in HMM. Objectives are: 1) Identify bottlenecks for implementation by CHW involved in HMM of SST; 2) determine impact of introducing SST in pregnancy on quality of HMM; 3) determine the impact of SST on ANC attendance and IPTp/SP coverage; 4) determine the impact of SST on LBW, anaemia and placenta malaria; 5) estimate cost-effectiveness of SST as compared to IPTp/SP alone and 6) formulate recommendations for possible implementation of the intervention.'
Introduzione (Teaser)
Low-cost interventions to manage malaria in resource-poor countries are of paramount importance. With a focus on pregnant women, the scope of the COSMIC initiative is to improve maternal and infant health in malaria-endemic countries.