PANCARELIFE
"PanCare Studies in Fertility and Ototoxicity to Improve Quality of Life after Cancer during Childhood, Adolescence and Young Adulthood"
| Coordinatore | UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ
Organization address
address: Langenbeckstrasse 1 contact info |
| Nazionalità Coordinatore | Germany [DE] |
| Sito del progetto | http://www.pancarelife.eu/ |
| Totale costo | 7˙806˙666 € |
| EC contributo | 5˙998˙279 € |
| Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
| Code Call | FP7-HEALTH-2013-INNOVATION-1 |
| Funding Scheme | CP-FP |
| Anno di inizio | 2013 |
| Periodo (anno-mese-giorno) | 2013-11-01 - 2018-10-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ
Organization address
address: Langenbeckstrasse 1 contact info |
DE (Mainz) | coordinator | 887˙824.20 |
| 2 |
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Organization address
address: 's Gravendijkwal 230 contact info |
NL (ROTTERDAM) | participant | 1˙074˙122.40 |
| 3 |
WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER
Organization address
address: SCHLOSSPLATZ 2 contact info |
DE (MUENSTER) | participant | 736˙780.80 |
| 4 |
STICHTING VU-VUMC
Organization address
address: DE BOELELAAN 1105 contact info |
NL (AMSTERDAM) | participant | 599˙162.80 |
| 5 |
UNIVERSITAET ZU LUEBECK
Organization address
address: RATZEBURGER ALLEE 160 contact info |
DE (LUEBECK) | participant | 508˙120.40 |
| 6 |
Academisch Medisch Centrum bij de Universiteit van Amsterdam
Organization address
address: MEIBERGDREEF 9 contact info |
NL (AMSTERDAM) | participant | 439˙247.20 |
| 7 |
BOYNE RESEARCH INSTITUTE LIMITED
Organization address
address: DUKE STREET DUKE HOUSE UNIT ONE contact info |
IE (DROGHEDA) | participant | 305˙303.20 |
| 8 |
UNIVERSITAET BERN
Organization address
address: Hochschulstrasse 4 contact info |
CH (BERN) | participant | 272˙099.20 |
| 9 |
ISTITUTO GIANNINA GASLINI
Organization address
address: VIA GEROLAMO GASLINI 5 contact info |
IT (GENOVA) | participant | 200˙819.20 |
| 10 |
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Organization address
address: Chariteplatz 1 contact info |
DE (BERLIN) | participant | 196˙342.00 |
| 11 |
FAKULTNI NEMOCNICE V MOTOLE
Organization address
address: V UVALU 84 contact info |
CZ (PRAHA 5) | participant | 195˙452.80 |
| 12 |
FAKULTNI NEMOCNICE BRNO
Organization address
address: JIHLAVSKA 20 contact info |
CZ (BRNO) | participant | 195˙155.20 |
| 13 |
PINTAIL LTD
Organization address
address: SPRINGHILL AVENUE 77 contact info |
IE (BLACKROCK) | participant | 159˙889.60 |
| 14 |
CENTRE HOSPITALIER UNIVERSITAIRE SAINT ETIENNE - CHU
Organization address
city: SAINT ETIENNE contact info |
FR (SAINT ETIENNE) | participant | 128˙351.20 |
| 15 |
KRAEFTENS BEKAEMPELSE
Organization address
address: Strandboulevarden 49 contact info |
DK (KOEBENHAVN) | participant | 99˙608.80 |
| 16 |
PRINSES MAXIMA CENTRUM VOOR KINDERONCOLOGIE BV
Organization address
address: DORPSSTR VO STEENSTR 12 contact info |
NL (DE BILT) | participant | 0.00 |
| 17 |
UNIVERSITATSKLINIKUM ERLANGEN
Organization address
address: Maximiliansplatz 2 contact info |
DE (ERLANGEN) | participant | 0.00 |
Mappa
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Obiettivo del progetto (Objective)
'Survival rates after childhood cancer now reach nearly 80% in developed European countries as a result of more effective therapies and better supportive care, leading to a steady increase in the number of survivors in the population. However, the treatments that have improved survival are harsh and cause serious side-effects that can greatly impact survivors’ quality of life in the long term. The goal of PanCareLIFE is that survivors of cancer diagnosed before age 25 should enjoy the same quality of life and opportunities as their peers who have not had cancer. Using observational studies and molecular genetic investigations PanCareLIFE will investigate late effects that impact fertility and hearing impairment (ototoxicity), and will assess health-related quality of life. Information from PanCareLIFE’s studies will be incorporated into new guidelines for fertility preservation. As the number of survivors with late effects in any one country is small, large cohorts are required for accurate estimation of risk. PanCareLIFE has assembled a team of prominent investigators from 8 European countries who will contribute in total over 12,000 well-characterised research subjects to identify risk factors, both genetic and non-genetic, linked to decrements in fertility and ototoxicity. Quality-of-life studies will evaluate the impact of fertility and ototoxicity. PanCareLIFE will advance the state-of-the-art in survivorship studies by evaluation of large cohorts with observational and genetic tools that will provide better knowledge of individual risk factors. Survivors can then be stratified into groups benefitting from personalized, evidence-based, care; future patients may expect effective therapies to have less severe side effects, and plans for a seamless transition to long-term follow-up care can be made. These approaches will result in better quality of life for survivors of cancer diagnosed at a young age.'