Coordinatore | ST. ANNA KINDERKREBSFORSCHUNG
Organization address
address: ZIMMERMANNPLATZ 10 contact info |
Nazionalità Coordinatore | Austria [AT] |
Totale costo | 7˙630˙575 € |
EC contributo | 5˙844˙418 € |
Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
Code Call | FP7-HEALTH-2013-INNOVATION-1 |
Funding Scheme | CP-FP |
Anno di inizio | 2014 |
Periodo (anno-mese-giorno) | 2014-02-01 - 2018-01-31 |
# | ||||
---|---|---|---|---|
1 |
ST. ANNA KINDERKREBSFORSCHUNG
Organization address
address: ZIMMERMANNPLATZ 10 contact info |
AT (WIEN) | coordinator | 1˙681˙240.00 |
2 |
MEDIZINISCHE UNIVERSITAET WIEN
Organization address
address: SPITALGASSE 23 contact info |
AT (WIEN) | participant | 1˙000˙918.00 |
3 |
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V
Organization address
address: Hansastrasse 27C contact info |
DE (MUENCHEN) | participant | 980˙616.60 |
4 |
GENEDATA AG
Organization address
address: MARGARETHENSTRASSE 38 contact info |
CH (BASEL) | participant | 968˙287.20 |
5 |
MOLZYM GMBH & CO KG
Organization address
address: KURFURSTENALLEE 23 A 23A contact info |
DE (BREMEN) | participant | 837˙485.80 |
6 |
JAVNA USTANOVA UNIVERZITET U TUZLI UNIVERSITAS STUDIORUM TUZLAENSIS
Organization address
address: DR TIHOMILA MARKOVICA 1 contact info |
BA (TUZLA) | participant | 375˙870.40 |
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'Invasive fungal disease (IFD) is a leading cause of morbidity and mortality in the growing number of immunocompromised individuals, including particularly cancer patients, and bone-marrow or organ transplant recipients. The majority of IFD events are still caused by Candida and Aspergillus species, but there is an increasing incidence of resistant or previously uncommon moulds, yeasts and Zygomycetes. Timely pathogen detection is a prerequisite for effective therapy in patients with IFD. FUNGITECT will focus on this medical priority and develop, validate and market a specific set of novel molecular diagnostic tests for IFD targeting fungal DNA-, RNA- and protein motifs, as well as the enzymatic activity of fungal pathogens. Additionally, FUNGITECT will provide a unique opportunity to establish and implement highly effective diagnostic assays supported by Next-Generation Sequencing and a bioinformatics service platform, facilitating optimized treatment strategies adapted to individual patient requirements with the following paramount aims: i) to provide the diagnostic basis for stratified and timely administration of the most appropriate antifungal therapy permitting improved management of patients with IFD, ii) to decrease the rate of overtreatment and the ensuing adverse side effects including fungal resistance, and iii) to help reduce the enormous healthcare costs for clinical antifungal therapy. The consortium includes leading academic research institutions, SMEs and Industry already successfully positioned in the market.'
Finding biomarkers of anti-microbial drug resistance via a systems biology analysis of fungal pathogen interactions with the human immune system
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