ACTIVE SNIFFING

The Algorithmic and Neuronal Basis of Active Sensing in the Case of Odor-Trail Tracking

 Coordinatore EBERHARD KARLS UNIVERSITAET TUEBINGEN 

 Organization address address: GESCHWISTER-SCHOLL-PLATZ
city: TUEBINGEN
postcode: 72074

contact info
Titolo: Dr.
Nome: Matthias
Cognome: Bethge
Email: send email
Telefono: +49 7071 29 89017
Fax: +49 7071 29 25015

 Nazionalità Coordinatore Germany [DE]
 Totale costo 252˙290 €
 EC contributo 252˙290 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2013-IOF
 Funding Scheme MC-IOF
 Anno di inizio 2014
 Periodo (anno-mese-giorno) 2014-08-01   -   2017-07-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    EBERHARD KARLS UNIVERSITAET TUEBINGEN

 Organization address address: GESCHWISTER-SCHOLL-PLATZ
city: TUEBINGEN
postcode: 72074

contact info
Titolo: Dr.
Nome: Matthias
Cognome: Bethge
Email: send email
Telefono: +49 7071 29 89017
Fax: +49 7071 29 25015

DE (TUEBINGEN) coordinator 252˙290.40

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

behavioral    sensory    trail    animal    guided    natural    reveal    navigation    population    active    yet    behaving    basis    behavior    sensing    encoded    odor    tracking    neuronal   

 Obiettivo del progetto (Objective)

'In its natural environment, any behaving animal is constantly bombarded with sensory information that must be parsed quickly by the animal to act appropriately. Yet, the nervous system is limited in the amount of information it can handle. Thus, to avoid sensory overload, specific aspects of these information streams have to be actively attended to by the animal. Such focusing is called active sensing and is a fundamental operational mode of many sensory systems. One ethologically important model for active sensing that has received increasing attention is odor-guided navigation in rodents. During odor-trail tracking, sniffing rates rise up to four times above the normal respiration frequency and each sniff selectively determines which part of the external world is sampled. Yet, an algorithmic understanding of their search strategy as well as its neuronal basis is lacking. My aims are to understand the neural representation of odors during this natural behavior and to reveal the neuronal basis of odor tracking behavior by following a multidisciplinary research program. I will develop an experimental setup that can flexibly deliver tightly controlled odor trails on a custom-build treadmill. By generating specifically tailored odor stimuli, I will be able to probe odor-guided navigation in real time and thus uncover the tracking algorithm. Moreover, I will record neuronal population activity from the early olfactory areas in mice that are following the trail. Such population activity in behaving animals can now be measured because of recent developments in miniature microscopes and genetically encoded calcium probes. I will show which aspects of the stimulus and behavioral variables are encoded by applying feature selection methods. Furthermore, by linking the behavioral decisions an animal takes during tracking to the recorded population response I will reveal which aspects of neuronal activity contribute to the tracking behavior in a mechanistic way.'

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