EIS

Development of a European Implementation Score for measuring implementation of research into healthcare practice using vascular disease as an example

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 Obiettivo del progetto (Objective)

'This collaborative project will develop a European methodology to assess the implementation of research evidence into practice (the European Implementation Score (EIS)), in primary, secondary and specialist care from the perspectives of different target groups (users and carers, voluntary organisations, range of health and social care professionals and health policy makers). The EIS will measure how well new knowledge is implemented into clinical practice in Europe. The EIS will address implementation of research knowledge at different levels of the health care system (micro-, meso- and macro-level) and in different health care settings (e.g. primary care, hospital, specialised care). The focus of the project will be in stroke because of the emerging new evidence of effective new treatments available and because of the national initiatives and governmental policies in this area. We will test the transferability of the develop methods using coronary heart disease as another vascular disease example. General recommendations for measuring effective implementation of research results will be developed from the perspectives of users, health care professionals and health policy, hence widening the theoretical framework for effective implementation from a focus on patients and professionals alone. The different components of the EIS will be refined according to their ability to predict successful implementation of evidence based stroke care in different settings in Europe. The identification of factors determining effective implementation will be data driven, analysing available data from national audits and population-based registers. The EIS will benchmark the current status of implementation of research results in different health care settings at different levels of the health care system and will inform health policy of a possible set of processes required for closing the research/practice gap.'

Introduzione (Teaser)

Implementing policy-driven research at a European level requires efficient and concerted methodologies. A scoring framework for identifying which aspects need to be addressed to improve the overall implementation of new treatments could significantly benefit European health care systems.

Descrizione progetto (Article)

Scientific and medical research aim to advance our understanding of how our body functions in health and disease, and to develop novel treatments. The implementation of research evidence in practice is suboptimal for many disease conditions, urgently requiring a more prompt transfer of research findings into clinical care.

The key goal of the EU-funded http://www.eisproject.com (EIS) initiative was to develop a European methodology for assessing the extent to which research evidence gets translated into clinical practice.

The so-called European Implementation Score (EIS) was envisaged as a measure of research knowledge implementation at different levels of the health care system and in different health care settings.Given the detrimental long-term consequences of cardiovascular diseases for the individual and society, the overall focus of the project was on stroke and implementation of the effective new treatments available. For this purpose, EIS project partners utilised data from 14 stroke registers and 2 coronary heart disease registers.

Application of a mathematical model to evaluate the impact of best practice on several European populations demonstrated reductions in mortality and cost. However, results from different health care systems across Europe indicated variable quality of stroke care, strongly arguing in favour of an EIS-based system.

To refine the components of the EIS scoring system, patients and health care professionals were involved in proposing recommendations. Current national methods for implementing and monitoring effective stroke care were reviewed, alongside drivers of effective research implementation. The consortium also identified performance measures and quality indicators for monitoring the effectiveness of stroke care, including diagnosis standards, prevention of complications and functional restoration.

The transferability of the EIS scoring system was tested in a comparative effectiveness study of acute myocardial infarction in Sweden and the United Kingdom. Results revealed clinically important differences in the uptake of effective treatments and outcomes between the two countries.

With the incidence of stroke predicted to rise dramatically in the next 20 years, the EIS collaborative project aimed to improve the health of EU citizens. Implementation of effective interventions such as stroke unit care and thrombolysis into health care systems in Europe is expected to provide quality care across the continent and reduce the burden of the disease.