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DOREMI

Low Dose Research towards Multidisciplinary Integration

Coordinatore	SATEILYTURVAKESKUS Organization address address: Laippatie 4 city: HELSINKI postcode: 881 contact info Titolo: Prof. Nome: Sisko Cognome: Salomaa Email: send email Telefono: +358 9 75988495 Fax: +358 9 75988498
Nazionalità Coordinatore	Finland [FI]
Totale costo	21˙291˙320 €
EC contributo	12˙999˙999 €
Programma	FP7-EURATOM-FISSION EURATOM: Nuclear fission and radiation protection
Code Call	FP7-Fission-2009
Funding Scheme	NoE
Anno di inizio	2010
Periodo (anno-mese-giorno)	2010-01-01 - 2015-12-31

Partecipanti

#	participant	country	role	EC contrib. [€]
1	SATEILYTURVAKESKUS Organization address address: Laippatie 4 city: HELSINKI postcode: 881 contact info Titolo: Prof. Nome: Sisko Cognome: Salomaa Email: send email Telefono: +358 9 75988495 Fax: +358 9 75988498	FI (HELSINKI)	coordinator	2˙022˙523.10
2	COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES Organization address address: RUE LEBLANC 25 city: PARIS 15 postcode: 75015 contact info Titolo: Mr. Nome: Oliver Cognome: Leroy Email: send email Telefono: +33 1 46549789 Fax: +33 1 46549180	FR (PARIS 15)	participant	1˙335˙700.20
3	HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH Organization address address: Ingolstaedter Landstrasse 1 city: MUENCHEN postcode: 85764 contact info Titolo: Dr. Nome: Juergen Cognome: Ertel Email: send email Telefono: +49 89 3187 3022 Fax: +49 89 3187 3866	DE (MUENCHEN)	participant	1˙320˙271.10
4	INSTITUT DE RADIOPROTECTION ET DE SURETE NUCLEAIRE Organization address address: Avenue de la Division Leclerc 31 city: FONTENAY AUX ROSES postcode: 92260 contact info Titolo: Mr. Nome: Didier Cognome: Mestraletti Email: send email Telefono: +33 1 58 35 83 31 Fax: +33 1 58 35 85 09	FR (FONTENAY AUX ROSES)	participant	1˙070˙542.00
5	UNIVERSITA DEGLI STUDI DI PAVIA Organization address address: STRADA NUOVA 65 city: PAVIA postcode: 27100 contact info Titolo: Dr. Nome: Maria Cognome: Brunelli Email: send email Telefono: +39 0382 987577 Fax: +39 0382 987752	IT (PAVIA)	participant	1˙040˙090.80
6	STOCKHOLMS UNIVERSITET Organization address address: Universitetsvaegen 10 city: STOCKHOLM postcode: 10691 contact info Titolo: Prof. Nome: Mats Cognome: Harms-Ringdahl Email: send email Telefono: +46 8 164109 Fax: +46 8 164315	SE (STOCKHOLM)	participant	664˙358.00
7	STUDIECENTRUM VOOR KERNENERGIE Organization address address: Herrmann Debrouxlaan 40 city: Brussel postcode: 1160 contact info Titolo: Dr. Nome: Sarah Cognome: Baatout Email: send email Telefono: 3214332729 Fax: 3214321056	BE (Brussel)	participant	517˙840.20
8	BUNDESAMT FUER STRAHLENSCHUTZ Organization address address: Willy-Brandt-Strasse 5 city: SALZGITTER postcode: 38226 contact info Titolo: Ms. Nome: Susan Cognome: Fischer Email: send email Telefono: +49 0 30 18333 1537 Fax: +49 30 18333 1525	DE (SALZGITTER)	participant	500˙102.75
9	OXFORD BROOKES UNIVERSITY Organization address address: HEADINGTON CAMPUS GIPSY LANE city: OXFORD postcode: OX3 OBP contact info Titolo: Mr. Nome: Mike Cognome: Barrett Email: send email Telefono: +44 1865 483243 Fax: +44 1865 488133	UK (OXFORD)	participant	389˙466.94
10	DUBLIN INSTITUTE OF TECHNOLOGY Organization address address: RATHMINES ROAD LOWER 143-149 city: DUBLIN postcode: 6 contact info Titolo: Dr. Nome: John Cognome: Donovan Email: send email Telefono: +353 1 402 8016 Fax: +353 1 402 3393	IE (DUBLIN)	participant	336˙453.50
11	ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Organization address address: 's Gravendijkwal 230 city: ROTTERDAM postcode: 3015CE contact info Titolo: Ms. Nome: Riet Cognome: Van Zeijl Email: send email Telefono: +31 10 70 43 154 Fax: +31 10 70 44 743	NL (ROTTERDAM)	participant	318˙000.00
12	AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE,L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE Organization address address: Lungotevere Grande Ammiraglio Thaon di Revel 76 city: ROMA postcode: 196 contact info Titolo: Dr. Nome: Valentina Cognome: Vaccaro Email: send email Telefono: +39 06 94005006 Fax: +39 06 36272376	IT (ROMA)	participant	303˙913.00
13	ACADEMISCH ZIEKENHUIS LEIDEN Organization address address: Albinusdreef 2 city: LEIDEN postcode: 2333 ZA contact info Titolo: Ms. Nome: Liesbeth Cognome: Dorama Email: send email Telefono: +31 71 5297351 Fax: +31 71 5268275	NL (LEIDEN)	participant	299˙808.00
14	Department of Health Organization address address: Quarry House, Quarry Hill city: Leeds postcode: LS2 7UE contact info Titolo: Mrs. Nome: Anne Cognome: Dempsey Email: send email Telefono: +44 1235 825433 Fax: +44 1235 833891	UK (Leeds)	participant	290˙153.72
15	FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL Organization address address: Calle Doctor Aiguader 88 city: BARCELONA postcode: 8003 contact info Titolo: Ms. Nome: Anna Cognome: Sillero Email: send email Telefono: +34 93 2147370	ES (BARCELONA)	participant	268˙030.50
16	ISTITUTO SUPERIORE DI SANITA Organization address address: Viale Regina Elena 299 city: ROMA postcode: 161 contact info Titolo: Dr. Nome: Rosa Maria Cognome: Martoccia Email: send email Telefono: 390650000000 Fax: 390650000000	IT (ROMA)	participant	262˙198.40
17	INSTITUT CURIE Organization address address: 26, rue d'Ulm city: PARIS postcode: 75248 contact info Titolo: Ms. Nome: Corinne Cognome: Cumin Email: send email Telefono: +33 1 56 24 66 20 Fax: +33 1 56 24 66 27	FR (PARIS)	participant	214˙794.00
18	UNIVERSITAET DER BUNDESWEHR MUENCHEN. Organization address address: WERNER HEISENBERG WEG 39 city: NEUBIBERG postcode: 85577 contact info Titolo: Prof. Nome: Günther Cognome: Dollinger Email: send email Telefono: 498960000000	DE (NEUBIBERG)	participant	210˙294.00
19	UNIVERSITAET DES SAARLANDES Organization address address: CAMPUS city: SAARBRUECKEN postcode: 66041 contact info Titolo: Prof. Nome: Claudia E. Cognome: Rübe Email: send email Telefono: +49 6841 1634614 Fax: +49 6841 1621401	DE (SAARBRUECKEN)	participant	189˙999.60
20	SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI Organization address address: Tsar Osvoboditel Blvd. 15 city: SOFIA postcode: 1504 contact info Titolo: Mr. Nome: Bojil Cognome: Dobrev Email: send email Telefono: +359 2 865 4686	BG (SOFIA)	participant	187˙350.00
21	ORSZAGOS FREDERIC JOLIOT-CURIE SUGARBIOLOGIAI ES SUGAREGESZSEGUGYI KUTATO INTEZET Organization address address: ANNA U 5 city: BUDAPEST postcode: 1221 contact info Titolo: Ms. Nome: Helga Cognome: Tamás Email: send email Telefono: +36 1 4822000 Fax: +36 1 4822003	HU (BUDAPEST)	participant	156˙972.00
22	HEALTH PROTECTION AGENCY HPA Organization address address: Central Office - 7th Floor, Holborn Gate - High Holborn 330 city: LONDON postcode: WC1V 7PP contact info Titolo: Ms. Nome: Beryl Cognome: Short Email: send email Telefono: +44 1235 822794 Fax: +44 1235 820 580	UK (LONDON)	participant	127˙658.00
23	UNIVERSITATSKLINIKUM ERLANGEN Organization address address: Maximiliansplatz 2 city: ERLANGEN postcode: 91054 contact info Titolo: Ms. Nome: Katrin Cognome: Faber Email: send email Telefono: +49 9131 85 35902 Fax: +49 9131 85 35903	DE (ERLANGEN)	participant	126˙000.00
24	Wojskowy Instytut Higieny i Epidemiologii Organization address address: Kozielska 4 city: Warsaw postcode: 01-163 contact info Titolo: Prof. Nome: Marek K. Cognome: Janiak Email: send email Telefono: +48 22 6818518 Fax: +48 22 8104391	PL (Warsaw)	participant	107˙440.00
25	JOHANN WOLFGANG GOETHE UNIVERSITAET FRANKFURT AM MAIN Organization address address: GRUNEBURGPLATZ 1 city: FRANKFURT AM MAIN postcode: 60323 contact info Titolo: Ms. Nome: Kseniya Cognome: Polozheyeva Email: send email Telefono: +49 69 6301 6848 Fax: +49 069 6301 81089	DE (FRANKFURT AM MAIN)	participant	105˙600.00
26	UNIVERSITAET ROSTOCK Organization address address: UNIVERSITATSPLATZ 1 city: ROSTOCK postcode: 18051 contact info Titolo: Prof. Nome: Guido Cognome: Hildebrandt Email: send email Telefono: +49 381 494 9001 Fax: +49 381 494 9002	DE (ROSTOCK)	participant	103˙800.00
27	UNIWERSYTET JAGIELLONSKI Organization address address: Ul. Golebia 24 city: KRAKOW postcode: 31007 contact info Titolo: Mr. Nome: Janusz Cognome: Kornecki Email: send email Telefono: +48 510 006 998 Fax: +48 12 2974615	PL (KRAKOW)	participant	92˙559.85
28	BRUNEL UNIVERSITY Organization address address: Kingston Lane city: UXBRIDGE postcode: UB83PH contact info Titolo: Ms. Nome: Teresa Cognome: Waller Email: send email Telefono: +44 1895 266206 Fax: +44 1895 269748	UK (UXBRIDGE)	participant	90˙873.00
29	LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN Organization address address: GESCHWISTER SCHOLL PLATZ 1 city: MUENCHEN postcode: 80539 contact info Titolo: Dr. Nome: Anna Cognome: Friedl Email: send email Telefono: +49 89 218075807 Fax: +49 89 2180 75 840	DE (MUENCHEN)	participant	90˙040.00
30	NUVIA LIMITED Organization address address: KELBOURN COURT DATEN PARK city: WARRINGTON postcode: WA3 6TW contact info Titolo: Ms. Nome: Julie Cognome: Makin Email: send email Telefono: +44 1235 514877 Fax: +44 1235 514857	UK (WARRINGTON)	participant	86˙387.00
31	AWE PLC Organization address address: ALDERMASTON city: READING postcode: RG7 4PR contact info Titolo: Mr. Nome: Rob Cognome: Glenn Email: send email Telefono: +44 118 982 5544 Fax: +44 118 981 5320	UK (READING)	participant	71˙561.30
32	STATNI USTAV RADIACNI OCHRANY v.v.i. Organization address address: BARTOSKOVA 28 city: Praha postcode: 14000 contact info Titolo: Mr. Nome: Vladislav Cognome: Huna Email: send email Telefono: +420 226518145 Fax: +420 241410215	CZ (Praha)	participant	62˙828.00
33	INSTYTUT MEDYCYNY PRACY NOFERA Organization address address: Teresy Street 8 city: LODZ postcode: 91348 contact info Titolo: Ms. Nome: Katarzyna Cognome: Kalska-Sochacka Email: send email Telefono: +48 42 631 48 39 Fax: +48 42 631 49 07	PL (LODZ)	participant	36˙390.00
34	INSTITUTE FOR ENVIRONMENTAL SCIENCES KOUEKI ZAIDAN HOUJIN Organization address address: IENOMAE 1-7 OBUCHI city: ROKKASHO MURA postcode: 039 3212 contact info Titolo: Dr. Nome: Tetsuya Cognome: Ono Email: send email Telefono: +81 175 71 1200 Fax: +81 175 72 3690	JP (ROKKASHO MURA)	participant	0.00
35	NASJONALT FOLKEHELSEINSTITUTT Organization address address: Lovisenberggata 8 city: OSLO postcode: 403 contact info Titolo: Ms. Nome: Lise Timm Cognome: Haug Email: send email Telefono: 4721076248 Fax: 4721076686	NO (OSLO)	participant	0.00
36	NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET Organization address address: UNIVERSITETSTUNET 3 city: AS postcode: 1430 contact info Titolo: Mr. Nome: Jan-Olav Cognome: Aasbo Email: send email Telefono: 4794965090 Fax: +47 64967505	NO (AS)	participant	0.00
37	NORWEGIAN RADIATION PROTECTION AUTHORITY Organization address address: GRINI NAERINGSPARK 13 city: OSTERAAS postcode: 1332 contact info Titolo: Ms. Nome: Lisbeth Hoydahl Cognome: Gundeid Email: send email Telefono: +47 67162582 Fax: +47 67147407	NO (OSTERAAS)	participant	0.00

Mappa

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risk questions gramme sensitivity expert transitional cutting platform jpr joint agenda infrastructure jpa members tissue doremi multidisciplinary join radiation training health sra cross network individual supporting strategic cancer epidemiological shape curve expanded shorter policy quality sustainable pro infrastructures hleg radioprotection doses dose internal integration group covering melodi national

Obiettivo del progetto (Objective)

'The aim of DoReMi is to promote the sustainable integration of low dose risk research in Europe in order to aid the effective resolution of the key policy questions identified by the High Level Expert Group (HLEG) on Low Dose Risk Research (www.hleg.de). DoReMi provides an operational tool for the development of the proposed MELODI platform (Multidisciplinary European Low Dose Risk Re-search Initiative) consisting of major national bodies and research programmes that have long term commitment in low dose risk research in Europe. A Letter of Intent between the core members of MELODI has been signed in April 2009. During the project, new members are expected to join the Initiative.

The Joint Programme of Activities (JPA) of DoReMi includes: (i) a Joint Programme of Research (JPR) covering the issues outlined above and providing an overview of the needs for research infra-structures of pan-European interest and facilitating multilateral initiatives leading to better use and development of research infrastructures; (ii) a Joint Programme of Integration (JPI) to develop a coor-dinated European roadmap for the long term needs of the key players in Europe; and (iii) a Joint Pro-gramme for the Spreading of Excellence (JPSE), covering knowledge management, training and mo-bility and its implementation. The JPR focuses on the areas identified by the HLEG as the most prom-ising in terms of addressing/resolving the key policy questions, namely: the shape of dose response curve for cancer, individual susceptibilities and non-cancer effects. Radiation quality, tissue sensitivity and internal exposures will be addressed as cross cutting themes within the three main research areas. A substantial proportion of the JPA will be dedicated to the joint programme of research. The pro-gramme describes a multidisciplinary approach including interfaces with the broader biological toxico-logical and epidemiological communities. Strategic planning will be carried out in close collaboration with MELODI. The long term Strategic Research Agenda (SRA) will be developed by MELODI, whereas DoReMi research priorities are based on a shorter term Transitional Research Agenda (TRA), focusing on goals that are feasible to achieve within the 6 year project and areas where barriers need to be removed in order to proceed with the longer term strategic objectives.'

Introduzione (Teaser)

Low doses of radiation from occupational hazards, medical diagnostic procedures and the environment are an increasing health concern. A new platform with the necessary expertise and infrastructure for research will address key policy issues.

Descrizione progetto (Article)

Sustainable integration of low-dose risk research in Europe is fundamental to improving the current state of radioprotection. The 'Low dose research towards multidisciplinary integration' (http://www.doremi-noe.net/ (DOREMI)) 6-year EU-funded project that started with 12 partners in 2010 and expanded to 36 by July 2014, is facilitating joint research, integration and training.

DOREMI is supporting the development of the Multidisciplinary European Low Dose Initiative (MELODI) proposed by the High Level and Expert Group (HLEG) on low-dose risk research. The MELODI platform will represent the major national organisations and research projects concerned with low-dose radiation risk. MELODI will develop a long-term Strategic Research Agenda (SRA) to resolve key policy issues identified by HLEG. DOREMI is establishing the more detailed shorter-term Transitional Research Agenda.

Many DOREMI activities are focused on the joint programme of research covering three areas: shape of the dose-response curve, individual sensitivities and non-cancer effects. In addition, all research activities address the cross-cutting issues of radiation quality, tissue sensitivity, and internal emitters and exposure.

Scientists have significantly expanded their network to include competence in fields such as biomarker identification, stem cells and genome reorganisation. Targeted training and education of next-generation researchers will ensure continuity and long-term success.

Experimental radiation research is dependent on access to radiation sources that are reliable, robust and accurate across a range of radiations. It also requires epidemiological infrastructure, databases and biobanks as well as analytical tools. DOREMI has successfully provided access to several new infrastructures that will enhance European capabilities for addressing key radioprotection issues. The website is a forum for information dissemination that encourages visitors to join the network and participate in activities.

Much is known about the effects of ionising radiation, but uncertainties and differing viewpoints exist as to the health effects of low doses. DOREMI is supporting the establishment of the MELODI platform to ensure a sustainable joint SRA to address issues of low-dose radiation risks. In light of indications that many EU Member States have lost key competences and cannot independently maintain effective radiation research programmes, organised and targeted cooperation could not have come at a better time.