MCCYC
METAL CATALYZED STRATEGIES FOR C-H BOND ACTIVATION AND CYCLOADDITION. SYNTHETIC APPLICATIONS AND DISCOVERY OF NON CONVETIONAL TRANSFORMATIONS
| Coordinatore | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
Organization address
address: "PAZO DE SAN XEROME, PRAZA DO OBRADOIRO S/N" contact info |
| Nazionalità Coordinatore | Spain [ES] |
| Totale costo | 45˙000 € |
| EC contributo | 45˙000 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-2009-RG |
| Funding Scheme | MC-ERG |
| Anno di inizio | 2010 |
| Periodo (anno-mese-giorno) | 2010-04-01 - 2013-03-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
Organization address
address: "PAZO DE SAN XEROME, PRAZA DO OBRADOIRO S/N" contact info |
ES (SANTIAGO DE COMPOSTELA) | coordinator | 45˙000.00 |
Mappa
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Obiettivo del progetto (Objective)
'Metal catalyzed C-H bond functionalization reactions is an area of organic synthesis having an exponential development and a great acceptation in the chemist community because meets the ideals of green chemistry. In this proposal we present a project research based on the development of new strategies of C-H bond activation/cycloaddition that leads to the formation of functionalized heterocycles. Furthermore the methodology is proposed to be applied to the synthesis of piperidine acid analogs, known prenyltransferase inhibitors. The inhibition of prenyltransferases could prevent the proper functioning of the Ras (protein), which is commonly abnormally active in cancer, and it could be key for the development of new therapeutics in the fight against this widespread illness.'