TENDON REGENERATION

Targeting Functional Tendon Regeneration Using a Loaded Biomimetic Scaffold. An Integrated Pan-European Approach

Coordinatore	NATIONAL UNIVERSITY OF IRELAND, GALWAY    more  Organization address address: University Road - city: GALWAY contact info Titolo: Ms. Nome: Mari Cognome: Vahey Email: send email Telefono: 35391495939
Nazionalità Coordinatore	Ireland [IE]
Totale costo	2˙256˙627 €
EC contributo	2˙256˙627 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2009-IAPP
Funding Scheme	MC-IAPP
Anno di inizio	2010
Periodo (anno-mese-giorno)	2010-09-01   -   2014-08-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	NATIONAL UNIVERSITY OF IRELAND, GALWAY  Organization address address: University Road - city: GALWAY contact info Titolo: Ms. Nome: Mari Cognome: Vahey Email: send email Telefono: 35391495939	IE (GALWAY)	coordinator	706˙438.00
2	Vornia Limited  Organization address address: "UPPER NEWCASTLE ROAD, BUSINESS INNOVATION CENTRE, NATIONAL UNIVERSITY OF IRELAND GALWAY" city: GALWAY postcode: 0 contact info Titolo: Mr. Nome: Colm Cognome: O'dowd Email: send email Telefono: 353877000000	IE (GALWAY)	participant	865˙856.00
3	THE HEBREW UNIVERSITY OF JERUSALEM.  Organization address address: GIVAT RAM CAMPUS city: JERUSALEM postcode: 91904 contact info Titolo: Ms. Nome: Jane Cognome: Turner Email: send email Telefono: +972 2 6586676 Fax: +972 2 6513205	IL (JERUSALEM)	participant	323˙606.00
4	CollPlant Ltd.  Organization address address: "SAPIR STREET, WEIZMANN SCIENCE Park 3" city: NESS ZIONA postcode: 74140 contact info Titolo: Mr. Nome: Adi Cognome: Rittner Ben-Zion Email: send email Telefono: +972 73 2325 600 Fax: +972 73 2325 602	IL (NESS ZIONA)	participant	270˙335.00
5	NORTH WEST TEXTILES NETWORK LIMITED  Organization address address: CHORLEY ROAD - PEEL HOUSE 2 city: BOLTON postcode: BL1 3AA contact info Titolo: Mr. Nome: Steve Cognome: Kay Email: send email Telefono: 441205000000	UK (BOLTON)	participant	90˙392.00
6	THE UNIVERSITY OF BOLTON  Organization address address: DEANE ROAD city: BOLTON postcode: BL3 5AB contact info Titolo: Ms. Nome: Donna Cognome: Zarei Email: send email Telefono: +44 01204 903101 Fax: +44 01204 903422	UK (BOLTON)	participant	0.00

Mappa

 Word cloud

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 Obiettivo del progetto (Objective)

'This industry-academia proposal addresses the development of technology which will enable understanding of regeneration of injured or degenerated tendons. Biomimetic fibrous composites will be designed and developed that will mimic the structure of native tendons. The project objectives are to fabricate an optimally stabilised and effectively functionalised three-dimensional collagen-resilin composite scaffold to match the properties of native tendons. Evaluation of the optimally stabilised and effectively functionalised biomimetic constructs will be conducted in vitro (cell studies, structural and mechanical properties) and in vivo (small and large animal studies). Using textile technologies, we aim to fabricate fibre extrusions that will allow future commercialisation of the three-dimensional biomimetic construct. In meeting the scientific and technological objectives of the IAPP Programme, an inter-sectorial academic industry multidisciplinary approach will be taken which maximises the potential offered by contemporary technologies This IAPP Programme will foster increased scientific dialogue between academics, industry and clinicians. One of the key benefits will be the transfer of key scientific and experimental knowledge between the institutions enabling the consortium to widen the scope of their work, beyond what is available within their own institution and merge the available technologies. This programme will provide training of both seconded and recruited staff, both in the host and parent institutions. This training will include experimental, communication and project management skills. Platform technologies developed during the lifetime of this project will result in future joint applications by partners in the consortium to the FP7 Health and FP7 NMP programmes.'

Introduzione (Teaser)

Tendons are fibrous connective tissues composed mostly of collagen, and connect muscle to bone to enable movement. Tendon injuries are not only painful but also disabling as they take a long time to heal.