GEOCODE

Genomic & Epigenomic Complex Disease Epidemiology

Coordinatore	UNIVERSITY OF BRISTOL    more  Organization address address: TYNDALL AVENUE SENATE HOUSE city: BRISTOL postcode: BS8 1TH contact info Titolo: Ms. Nome: Elodie Cognome: Mahieu-Wedande Email: send email Telefono: 441173000000 Fax: 441179000000
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	772˙200 €
EC contributo	772˙200 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2009-IRSES
Funding Scheme	MC-IRSES
Anno di inizio	2010
Periodo (anno-mese-giorno)	2010-03-01   -   2014-02-28

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	UNIVERSITY OF BRISTOL  Organization address address: TYNDALL AVENUE SENATE HOUSE city: BRISTOL postcode: BS8 1TH contact info Titolo: Ms. Nome: Elodie Cognome: Mahieu-Wedande Email: send email Telefono: 441173000000 Fax: 441179000000	UK (BRISTOL)	coordinator	365˙400.00
2	UNIVERSITY OF NEWCASTLE UPON TYNE  Organization address address: Kensington Terrace 6 city: NEWCASTLE UPON TYNE postcode: NE1 7RU contact info Titolo: Ms. Nome: Aleona Cognome: Blinova Email: send email Telefono: 441913000000 Fax: +44 191 282 0064	UK (NEWCASTLE UPON TYNE)	participant	171˙000.00
3	CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER  Organization address address: Cours Albert-Thomas 150 city: LYON CEDEX 08 postcode: 69372 contact info Titolo: Dr. Nome: Olaf Cognome: Kelm Email: send email Telefono: 33472738494 Fax: 33472738564	FR (LYON CEDEX 08)	participant	54˙000.00
4	UNIVERSITY OF SOUTHAMPTON  Organization address address: Highfield city: SOUTHAMPTON postcode: SO17 1BJ contact info Titolo: Prof. Nome: Caroline Cognome: Fall Email: send email Telefono: 442381000000 Fax: 442381000000	UK (SOUTHAMPTON)	participant	45˙000.00
5	ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM  Organization address address: 's Gravendijkwal 230 city: ROTTERDAM postcode: 3015CE contact info Titolo: Mr. Nome: Koos Cognome: Lubbe Email: send email Telefono: +31 10 7043405 Fax: +31 10 4089370	NL (ROTTERDAM)	participant	41˙400.00
6	THE UNIVERSITY OF EXETER  Organization address address: Northcote House, The Queen's Drive city: EXETER postcode: EX4 4QJ contact info Titolo: Dr. Nome: Enda Cognome: Clarke Email: send email Telefono: 441392000000 Fax: 441392000000	UK (EXETER)	participant	37˙800.00
7	UNIVERSITA DEGLI STUDI DI TORINO  Organization address address: Via Giuseppe Verdi 8 city: TORINO postcode: 10124 contact info Titolo: Dr. Nome: Emanuela Cognome: Ciliberto Email: send email Telefono: 390116000000 Fax: 390116000000	IT (TORINO)	participant	30˙600.00
8	FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL  Organization address address: Calle Doctor Aiguader 88 city: BARCELONA postcode: 8003 contact info Titolo: Ms. Nome: Gemma Cognome: Perelló Email: send email Telefono: +34 93 214 73 70 Fax: +34 93 214 73 02	ES (BARCELONA)	participant	27˙000.00

Mappa

 Word cloud

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 Obiettivo del progetto (Objective)

Genetic and epigenetic epidemiology are rapidly developing aspects of population-based health research that have clear translational potential. These endeavours both benefit considerably from extensive international collaborations. Establishing robust associations between genetic variation and common complex disease phenotypes requires very large sample sizes than can only realistically be generated through collaborative work. Furthermore, exploring associations in populations with different historical origins contributes to location of functional variation. Interactions of genetic variation and environmental exposures are best studied against a background of widely different environments, something that is best leveraged between, rather than within, countries. Epigenetic patterns are clearly influenced by exposures such as 1-carbon composition of the diet that differ between countries, allowing considerably greater power for establishing associations. Triangulating environmental exposures, genetic variation and epigenetic mediation offers to provide a step-change in ability to detect causal associations, of direct relevance to therapeutic and preventive activities. GeoCoDE will assemble a group of investigators who are custodians of world-leading population resources, have access to appropriate technologies and have been involved in advancing methods of data analysis. Through exchange visits of senior and junior research staff, workshops and extensive networking we will contribute to major advance in European capacity in this field.

Introduzione (Teaser)

Tackling complex diseases such as cancer and obesity requires an integrated approach. An EU-funded joint exchange programme has gathered extensive environmental, genetic and epigenetic data in Europe and third countries to strengthen research capacity for therapeutic and preventative measures.