GEOCODE
Genomic & Epigenomic Complex Disease Epidemiology
| Coordinatore | UNIVERSITY OF BRISTOL
Organization address
address: TYNDALL AVENUE SENATE HOUSE contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Totale costo | 772˙200 € |
| EC contributo | 772˙200 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-2009-IRSES |
| Funding Scheme | MC-IRSES |
| Anno di inizio | 2010 |
| Periodo (anno-mese-giorno) | 2010-03-01 - 2014-02-28 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
UNIVERSITY OF BRISTOL
Organization address
address: TYNDALL AVENUE SENATE HOUSE contact info |
UK (BRISTOL) | coordinator | 365˙400.00 |
| 2 |
UNIVERSITY OF NEWCASTLE UPON TYNE
Organization address
address: Kensington Terrace 6 contact info |
UK (NEWCASTLE UPON TYNE) | participant | 171˙000.00 |
| 3 |
CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER
Organization address
address: Cours Albert-Thomas 150 contact info |
FR (LYON CEDEX 08) | participant | 54˙000.00 |
| 4 |
UNIVERSITY OF SOUTHAMPTON
Organization address
address: Highfield contact info |
UK (SOUTHAMPTON) | participant | 45˙000.00 |
| 5 |
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Organization address
address: 's Gravendijkwal 230 contact info |
NL (ROTTERDAM) | participant | 41˙400.00 |
| 6 |
THE UNIVERSITY OF EXETER
Organization address
address: Northcote House, The Queen's Drive contact info |
UK (EXETER) | participant | 37˙800.00 |
| 7 |
UNIVERSITA DEGLI STUDI DI TORINO
Organization address
address: Via Giuseppe Verdi 8 contact info |
IT (TORINO) | participant | 30˙600.00 |
| 8 |
FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL
Organization address
address: Calle Doctor Aiguader 88 contact info |
ES (BARCELONA) | participant | 27˙000.00 |
Mappa
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Obiettivo del progetto (Objective)
Genetic and epigenetic epidemiology are rapidly developing aspects of population-based health research that have clear translational potential. These endeavours both benefit considerably from extensive international collaborations. Establishing robust associations between genetic variation and common complex disease phenotypes requires very large sample sizes than can only realistically be generated through collaborative work. Furthermore, exploring associations in populations with different historical origins contributes to location of functional variation. Interactions of genetic variation and environmental exposures are best studied against a background of widely different environments, something that is best leveraged between, rather than within, countries. Epigenetic patterns are clearly influenced by exposures such as 1-carbon composition of the diet that differ between countries, allowing considerably greater power for establishing associations. Triangulating environmental exposures, genetic variation and epigenetic mediation offers to provide a step-change in ability to detect causal associations, of direct relevance to therapeutic and preventive activities. GeoCoDE will assemble a group of investigators who are custodians of world-leading population resources, have access to appropriate technologies and have been involved in advancing methods of data analysis. Through exchange visits of senior and junior research staff, workshops and extensive networking we will contribute to major advance in European capacity in this field.
Introduzione (Teaser)
Tackling complex diseases such as cancer and obesity requires an integrated approach. An EU-funded joint exchange programme has gathered extensive environmental, genetic and epigenetic data in Europe and third countries to strengthen research capacity for therapeutic and preventative measures.