SINGLESENS

Single metal nanoparticles as molecular sensors

Coordinatore	JOHANNES GUTENBERG UNIVERSITAET MAINZ    more Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.
Nazionalità Coordinatore	Germany [DE]
Totale costo	1˙510˙000 €
EC contributo	1˙510˙000 €
Programma	FP7-IDEAS-ERC Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	ERC-2010-StG_20091028
Funding Scheme	ERC-SG
Anno di inizio	2011
Periodo (anno-mese-giorno)	2011-01-01   -   2015-12-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	JOHANNES GUTENBERG UNIVERSITAET MAINZ  Organization address address: SAARSTRASSE 21 city: MAINZ postcode: 55099 contact info Titolo: Ms. Nome: Julia Cognome: Doré Email: send email Telefono: +49 6131 3926865 Fax: +49 6131 3924741	DE (MAINZ)	hostInstitution	1˙510˙000.00
2	JOHANNES GUTENBERG UNIVERSITAET MAINZ  Organization address address: SAARSTRASSE 21 city: MAINZ postcode: 55099 contact info Titolo: Prof. Nome: Carsten Cognome: Sönnichsen Email: send email Telefono: +49 6131 3924313 Fax: +49 6131 3926747	DE (MAINZ)	hostInstitution	1˙510˙000.00

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 Obiettivo del progetto (Objective)

'Optical spectroscopy of single plasmonic nanoparticles (NPs) has evolved into a recognized tool for nanoscopic sensing applications, using the sensitivity to the NP's environment,charge, size, shape, and proximity to other NPs. Here, I propose taking advantage of the nanoparticle s minuscule size approaching molecular dimensions in novel ways. Single particle plasmon sensors are in many ways the smallest possible giving unprecedented access to molecular events. The small size amplifies fluctuations by molecular events, allows massive parallel detection of analytes within tiny devices, and to monitor single nanoparticle formation and electrochemical surface reactions in real time. The objective of this project is therefore to develop and explore single-particle plasmon spectroscopy as a novel tool to study such molecular processes. The objective will be reached by (1) building three new setups progressing far beyond current technology and increasing time resolution, spectral sensitivity, and parallelization capability many orders of magnitude, (2) synthesizing nanoparticles with optimal plasmon sensing properties, and (3) simulating plasmon properties to guide the experiments and understand the physics behind the observed phenomena. The single-particle plasmon spectroscopy technique will be applied in four scientific directions to demonstrate its potential: (4) analyzing distance fluctuations of particle pairs linked by (bio-)polymers, (5) recording coverage fluctuations of biomolecules bound to nanoparticles, (6) demonstrating parallel detection of many analytes in multiplexed microfluidic devices, and (7) following particle formation and chemical reactions in a single particle reactor . Single-particle plasmon spectroscopy has the potential to provide a revolutionary new tool to study molecular processes and to become a major commercial analytical tool, especially for pharmaceutical research and development.'