EUROBATS
Identifying biomarkers of ageing using whole transcriptomic sequencing
| Coordinatore | KING'S COLLEGE LONDON
Organization address
address: Strand contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Sito del progetto | http://www.eurobats.eu |
| Totale costo | 3˙920˙729 € |
| EC contributo | 2˙998˙649 € |
| Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
| Code Call | FP7-HEALTH-2010-two-stage |
| Funding Scheme | CP-FP |
| Anno di inizio | 2011 |
| Periodo (anno-mese-giorno) | 2011-01-01 - 2014-06-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
KING'S COLLEGE LONDON
Organization address
address: Strand contact info |
UK (LONDON) | coordinator | 1˙179˙286.00 |
| 2 |
UNIVERSITE DE GENEVE
Organization address
address: Rue du General Dufour 24 contact info |
CH (GENEVE) | participant | 1˙094˙400.00 |
| 3 |
FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III
Organization address
address: CALLE MELCHOR FERNANDEZ ALMAGRO 3 contact info |
ES (MADRID) | participant | 381˙179.75 |
| 4 |
GENOME RESEARCH LIMITED
Organization address
address: THE GIBBS BUILDING, EUSTON ROAD 215 contact info |
UK (LONDON) | participant | 237˙728.00 |
| 5 |
LIFE LENGTH SL
Organization address
address: CALLE AGUSTIN DE BETANCOURT 21 contact info |
ES (MADRID) | participant | 106˙056.00 |
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Obiettivo del progetto (Objective)
'Ageing is a fundamental biological process that defines all aspects of life, yet the understanding of the basic biological interactions leading to ageing and how genetic and environmental variation contributes to this processes are still largely unknown. We propose to use the most up to date genomic and epidemiological methodologies to shed light in some of the key questions in ageing research. We will use whole transcriptome sequencing, and telomere length assays in three cell types of 855 twins for which a large set of phenotypic measurements relating to ageing are available. These datasets will be integrated with genome-wide association studies in a systems genetics framework to infer causal interactions (genetic or environmental). The combination of these unique datasets together with the expertise of the participants is likely to provide novel insights to ageing research and uncover currently unknown factors that contribute to variation in the ageing process in human populations.'