PHOTPROT

The Dynamic Protein Matrix in Photosynthesis: From Disorder to Life

Coordinatore	STICHTING VU-VUMC    more Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.
Nazionalità Coordinatore	Netherlands [NL]
Totale costo	2˙864˙400 €
EC contributo	2˙864˙400 €
Programma	FP7-IDEAS-ERC Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	ERC-2010-AdG_20100224
Funding Scheme	ERC-AG
Anno di inizio	2011
Periodo (anno-mese-giorno)	2011-02-01   -   2017-01-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES  Organization address address: RUE LEBLANC 25 city: PARIS 15 postcode: 75015 contact info Titolo: Ms. Nome: Eliane Cognome: Deck-Chaumont Email: send email Telefono: +33 169082009 Fax: +33 169083551	FR (PARIS 15)	beneficiary	691˙783.30
2	VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG  Organization address address: De Boelelaan 1105 city: AMSTERDAM postcode: 1081 HV contact info Titolo: Ms. Nome: Dirkje Cognome: Schinkelshoek Email: send email Telefono: +31 20 5987500	NL (AMSTERDAM)	beneficiary	0.00
3	STICHTING VU-VUMC  Organization address address: DE BOELELAAN 1105 city: AMSTERDAM postcode: 1081 HV contact info Titolo: Dr. Nome: Yvonne Cognome: Kops Email: send email Telefono: 31205987500	NL (AMSTERDAM)	hostInstitution	2˙172˙616.80
4	STICHTING VU-VUMC  Organization address address: DE BOELELAAN 1105 city: AMSTERDAM postcode: 1081 HV contact info Titolo: Prof. Nome: Rienk Cognome: Van Grondelle Email: send email Telefono: 31205987930	NL (AMSTERDAM)	hostInstitution	2˙172˙616.80

Mappa

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 Obiettivo del progetto (Objective)

'In photosynthesis solar light is harvested by an antenna, the energy is transferred to the photosynthetic reaction center where a charge separation occurs. These processes occur on an ultrafast timescale and result in a stable product. The photosynthetic apparatus consists of a complex set of pigment-proteins that perform these delicate processes with a quantum efficiency close to 1. Proteins are intrinsically disordered and display dynamics over a fast range oof times, from femtoseconds to seconds. In this proposal I wish to explore how this dynamic protein matrix facilitates or maybe even drives the primary events of photosynthesis. Together with my co-investigator Bruno Robert I plan to investigate four aspects of how the protein matrix may affect this important biological process. In the first project we will study if the charge separation in Photosystem 2 occurs along multiple pathways, depending on the realization of the disorder. Project 2 concerns the possible role of quantum coherence in charge separation in Photosystem 2. In project 3 we will investigate how the dynamic protein matrix maybe even actively stabilizes the early charge separation. Project 4 aims to find out how functional transitions in photosynthetic proteins are coupled to conformational changes. The latter relates to the idea that the peripheral light-harvesting complex of plants, LHCII, plays a role in photoprotection by switching between a light-harvesting state and a quenching state. The project combines a number of state-of-the-art biophysical approaches and furthermore aims to develop new techniques: 2-dimensional electronic spectroscopy and plasmon wave resonance spectroscopy. The final result will deliver a unique view on how the physics of protein matter manifests itself in biology.'