The page lists 62 projects related to the topic "ubiquitin".
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1 | 20SComplexity | An integrative approach to uncover the multilevel regulation of 20S proteasome degradation | 2015 |
2 | Autophagy in vitro | Reconstituting Autophagosome Biogenesis in vitro | 2015 |
3 | RINGE3 | Structural and mechanistic insights into RING E3-mediated ubiquitination | 2015 |
4 | UbiProPox | Modulation of the Ubiquitin Proteasome System During Multiple Stages of the Poxvirus Lifecycle | 2015 |
5 | OTULINVIVO | The role of OTULIN and Met1-linked ubiquitin in immune signaling and host defense in vivo | 2015 |
6 | SYNPT | The role of autophagy in presynaptic protein turnover | 2015 |
7 | EMCOP9CRL | Structural basis of Cullin-RING ligase regulation by the COP9 signalosome | 2015 |
8 | APCINTERACTIONS | Molecular basis for securin and cyclin ubiquitylation by the anaphase-promoting complex (APC/C) | 2016 |
9 | YIELDFACTOR | Using SP1 to control plastid development and yield in cereals | 2016 |
10 | REALISM | Reducing Early Atrophy with Leucine during Immobilization of Skeletal Muscle | 2015 |
11 | IntestineUb | The role of Ubiquitin System on the homeostatic control of stem cell maintenance and differentiation in crypt stem cells | 2016 |
12 | UbiGABA | The role of ubiquitination in stability and plasticity of the GABAergic synapse | 2015 |
13 | SUMOblock | Blocking SUMO conjugation as drug discovery strategy. | 2015 |
14 | AutoRecon | Molecular mechanisms of autophagosome formation during selective autophagy | 2016 |
15 | AUROMYC | N-Myc and Aurora A: From Protein Stability to Chromosome TopologyN-Myc and Aurora A: From Protein Stability to Chromosome TopologyMyc and Aurora A: From Protein Stability to Chromosome Topology | 2015 |
16 | DUB-DECODE | Systematic Decoding of Deubiquitylase-Regulated Signaling Networks | 2015 |
17 | CsnCRL | The molecular basis of CULLIN E3 ligase regulation by the COP9 signalosome | 2016 |
18 | IMMUNE-EXPRESS | Proteasome-Mediated Gene Expression in Plant Immunity | 2016 |
19 | RELYUBL | Regulation of lymphocyte biology by ubiquitin and ubiquitin like modifiers | 2016 |
20 | SynDegrade | The Role of Local Protein Degradation in Neurotransmitter Release and Homeostatic Plasticity | 2016 |
21 | ANCHOR E3s | Anchoring ligandable binding sites at E3 ligase surfaces for plug-and-play PROTACs. | 2016 |
22 | ChondUb | Identification and characterisation of novel WWP2 substrates and their role in chondrogenesis and osteoarthritis | 2016 |
23 | SiCMetabol | Signaling Cascades in Metabolic Diseases | 2016 |
24 | Ubl-Code | Revealing the ubiquitin and ubiquitin-like modification landscape in health and disease | 2016 |
25 | ICLUb | Regulation of DNA interstrand crosslink repair by ubiquitin. | 2016 |
26 | pArg_deg_signal | No stress with pArg: Mechanisms of a distinct phospho-mark to coordinate stress response and protein quality control | 2016 |
27 | BCM-UPS | Dissecting the role of the ubiquitin proteasome system in the pathogenesis and therapy of B-cell malignancies | 2016 |
28 | ERCOPE | The ER located master regulation of endosomal positioning and further movements | 2016 |
29 | DIAL-IN | Dynamic Integrated structural and proteomic Analysis of the LUBAC complex and its involvement in NF-κB and inflammation | 2016 |
30 | LIGER | Identification of novel substrates for ubiquitin ligases involved in cell cycle and cell migration | 2017 |
31 | Cytokineproteomics | Investigating inflammatory signaling by combining phospho- and ubiquitin proteomics with CRISPR/Cas9 technology | 2017 |
32 | UBIMAPS | Ubiquitin-dependent regulation of the microtubule cytoskeleton | 2017 |
33 | PHOSPH-UBIQ-IMMUN | Dynamic interplay between phosphorylation and ubiquitination during plant receptor kinase-mediated immunity | 2017 |
34 | HUNTINFISH | Generation of new zebrafish models for the study of the pathogenesis of Huntington´s disease and for the identification of new therapeutic targets. | 2018 |
35 | UbiArchitect | Understanding the complexity and architecture in protein ubiquitination | 2017 |
36 | IMMUNO-RQC | Role of Listerin ubiquitin ligase in MHC-I antigen presentation | 2017 |
37 | PFIMDULA | Post-translational modifications during floral initiation: molecular dissection of the UFO-dependent LFY activation | 2017 |
38 | DUBs26S | Role of a novel proteasome-associated DUB – A boon for therapeutics | 2017 |
39 | Ub-BAC | Dissecting and targeting ubiquitin networks in the course of bacterial infections | 2017 |
40 | UbiCODE | European Research Training to Decipher The Ub Code : identification of potential biomarkers and drug targets | 2018 |
41 | UBIQUITON | Development of a tool kit to investigate protein ubiquitylation in biomedical research | 2018 |
42 | GOKNOT | Modelling the formation of a gordian knot in Human Ubiquitin Hydrolase | 2018 |
43 | Alpha-Synuclein | Blocking the prion-like disease propagation in Parkinson’s disease and related disorders – model development and identification of cell-autonomous and cell non-autonomous factors. | 2019 |
44 | NEUROGUIDE | Study of neuronal sensing and migration/guidance dynamics in neurodevelopmental disorders by nano-engineered chips | 2018 |
45 | DIM | Decoding ISGylation events in Macrophages | 2018 |
46 | UB-RASDisease | The ubiquitin system in RAS-driven disease | 2018 |
47 | Nedd8Activate | How does the ubiquitin-like protein NEDD8 activate ubiquitin ligase machineries? | 2018 |
48 | HEIREC | HEI10-mediated elevations in bread wheat recombination | 2018 |
49 | DETRIMODE | DEgradation TRIggered by MOdular DEsign | 2018 |
50 | MicroMAM | The mammalian intracellular response to Microsporidia infection | 2019 |
51 | TRIM-NET | Training network in drug discovery targeting TRIM Ubiquitin ligases in disease | 2019 |
52 | CuRE | Cardiac REgeneration from within | 2019 |
53 | UbiGolD | Deciphering ubiquitin-dependent regulation of Golgi homeostasis control in neurodegeneration | 2019 |
54 | Degradation_ID | The role of protein degradation in FBXO11-related intellectual disability | 2019 |
55 | H2AH2B_Propagation | Elucidating the propagation and function of H2A and H2B modifications across DNA replication | 2020 |
56 | TargetDUBs | Targeting ubiquitin processing in cancer and fibrosis: novel probes for the Ubiquitin Carboxy-Terminal Hydrolases | 2019 |
57 | SynProAtCell | Delivery and On-Demand Activation of Chemically Synthesized and Uniquely Modified Proteins in Living Cells | 2019 |
58 | NCI-CAD | Neutrophil - Chlamydia interactions at the crossroad of adaptation and defence | 2019 |
59 | UBIMOTIF | Short linear interaction motifs as specificity determinants in the ubiquitin system – discovery, mechanisms and therapeutic opportunities | 2019 |
60 | CHANCE | Structure guided inhibition of IDOL to treat atherosclerosis and the metabolic syndrome | 2019 |
61 | PANDORA | Pandemics Outbreaks Rationalized: towards a universal therapy to eliminate intracellular pathogens and drug resistance | 2020 |
62 | CHUbVi | Ubiquitin Chains in Viral Infections | 2020 |