Explore the words cloud of the PFIMDULA project. It provides you a very rough idea of what is the project "PFIMDULA" about.
The following table provides information about the project.
Coordinator |
COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
Organization address contact info |
Coordinator Country | France [FR] |
Project website | http://www.lpcv.fr/Flo_Re |
Total cost | 185˙076 € |
EC max contribution | 185˙076 € (100%) |
Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
Code Call | H2020-MSCA-IF-2016 |
Funding Scheme | MSCA-IF-EF-ST |
Starting year | 2017 |
Duration (year-month-day) | from 2017-06-08 to 2019-06-07 |
Take a look of project's partnership.
# | ||||
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1 | COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES | FR (PARIS 15) | coordinator | 185˙076.00 |
Flowering plants are the most successful plant group on Earth and provide the basis for most human and animal food. The development of flowers is dependent on a gene regulatory network orchestrated by LEAFY (LFY), the master transcription factor. In Arabidopsis as in other flowering plants, LFY activity is dependent upon its interaction with UFO, a member of the Skp1–Cullin–F-box E3 ubiquitin ligase complex. The goal of this project is to understand why LFY requires interacting with UFO to build flowers. For this, we will apply state-of-the-art technologies including mass-spectrometry, crystallography, biochemistry and plant developmental genetics to identify and characterize the function of Post-Translational Modifications (PTM) on LFY or LFY interacting proteins, with special emphasis on ubiquitination. After identifying key residues involved in the LFY-UFO interaction or targeted by PTM, their functional importance will be assayed in planta. This project should facilitate better understanding of the mechanism of LFY activation. LEAFY and the development of flower will be used here as a model to understand the “activation by degradation” mechanism, still elusive in most organisms and poorly studied in plants. Moreover, understanding the principles governing LFY activation should provide means to modify at will the architecture of plant inflorescences. This project builds on the current background of the applicant in the field of Mass-Spectrometry combined with the outstanding expertise at Grenoble and high-throughput facilities in Structural biology and plant developmental genetics. Notably, the applicant will work within one of the top French Research Centers and in a multidisciplinary environment that will allow the fellow to acquire complementary ‘new knowledge and skills’ in structural biology and developmental genetics. This will re-enforce the fellow’s background and professional maturity for employment opportunities in both academia and industry sectors.
year | authors and title | journal | last update |
---|---|---|---|
2018 |
Claudius Marondedze, Xinyun Liu, Shihui Huang, Cynthia Wong, Xuan Zhou, Xutong Pan, Huiting An, Nuo Xu, Xuechen Tian, Aloysius Wong Towards a tailored indoor horticulture: a functional genomics guided phenotypic approach published pages: , ISSN: 2052-7276, DOI: 10.1038/s41438-018-0065-7 |
Horticulture Research 5/1 | 2019-08-05 |
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The information about "PFIMDULA" are provided by the European Opendata Portal: CORDIS opendata.
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