Explore the words cloud of the BetaDropNMR project. It provides you a very rough idea of what is the project "BetaDropNMR" about.
The following table provides information about the project.
Coordinator |
EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH
Organization address contact info |
Coordinator Country | Switzerland [CH] |
Total cost | 1˙500˙000 € |
EC max contribution | 1˙500˙000 € (100%) |
Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
Code Call | ERC-2014-STG |
Funding Scheme | ERC-STG |
Starting year | 2015 |
Duration (year-month-day) | from 2015-10-01 to 2021-09-30 |
Take a look of project's partnership.
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1 | EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH | CH (GENEVA 23) | coordinator | 1˙500˙000.00 |
'The nuclear magnetic resonance spectroscopy (NMR) is a versatile and powerful tool, especially in chemistry and in biology. However, its limited sensitivity and small amount of suitable probe nuclei pose severe constraints on the systems that may be explored. This project aims at overcoming the above limitations by giving NMR an ultra-high sensitivity and by enlarging the NMR 'toolbox' to dozens of nuclei across the periodic table. This will be achieved by applying the β-NMR method to the soft matter samples. The method relies on anisotropic emission of β particles in the decay of highly spin-polarized nuclei. This feature results in 10 orders of magnitude more sensitivity compared to conventional NMR and makes it applicable to elements which are otherwise difficult to investigate spectroscopically. β-NMR has been successfully applied in nuclear physics and material science in solid samples and high-vacuum environments, but never before to liquid samples placed in atmospheric pressure. With this novel approach I want to create a new universal and extremely sensitive tool to study various problems in biochemistry. The first questions which I envisage addressing with this ground-breaking and versatile method concern the interaction of essential metal ions, which are spectroscopically silent in most techniques, Mg2, Cu, and Zn2, with proteins and nucleic acids. The importance of these studies is well motivated by the fact that half of the proteins in our human body contain metal ions, but their interaction mechanism and factors influencing it are still not fully understood. In this respect NMR spectroscopy is of great help: it provides information on the structure, dynamics, and chemical properties of the metal complexes, by revealing the coordination number, oxidation state, bonding situation and electronic configuration of the interacting metal. My long-term aim is to establish a firm basis for β-NMR in soft matter studies in biology, chemistry and physics.'
year | authors and title | journal | last update |
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2018 |
M. Jankowski Enabling beta-Decay Asymmetry Measurements onLiquid Samples at the Versatile Ion-PolarizationTechniques Online (VITO) Beam Line published pages: , ISSN: , DOI: |
Bachelor Thesis | 2019-10-07 |
2018 |
M. Bissell1, R.F. Garcia-Ruiz1, W. Gins, M. Kowalska, G. Neyens2, S. Pallada, N. Severijns2, P.
Velten2, F. Wienholtz, D. Zakoucky4, X.F. Yang2 Online commissioning of the laser-polarization setup at VITO published pages: , ISSN: , DOI: |
Letter of Intent to the ISOLDE and Neutron Time-of-Flight Committee CERN-INTC-2016-026 / INTC-I-168 | 2019-10-07 |
2017 |
M. Kowalska1, V. Araujo Escalona2, M. Baranowski3, L. Cerato4, M. Bissell4, W. Gins2, R. Grzywacz6, F. Gustafsson2, R. Harding, L. Hemmingsen8, F. Hofmann8, H. Heylen9, A. Kanellakopoulos2, V. Kocman10, M. Kozak3, M. Madurga Flores6, G. Neyens2, S. Pallada, J. Plavec10, N. Severijns2, D. Szunyogh8, K. Szutkowski3, P. Thulstrup8, M. Walczak11, F. Wienholtz, J. Wolak3, X.F. Yang2, D. Zakoucky12 Interaction of Na ions with DNA G-quadruplex structuresstudied directly with Na beta-NMR spectroscopy published pages: , ISSN: , DOI: |
Proposal to the ISOLDE and Time-of-Flight Committee CERN-INTC-2017-071 / INTC-P-521 | 2019-10-07 |
2018 |
M. Kowalska1, V. Araujo Escalona2, M. Baranowski3, J. Croese1,4, L. Cerato4, M. Bissell4, W.
Gins2, F. Gustafsson2, R. Harding, L. Hemmingsen8, H. Heylen1, F. Hofmann8, A.
Kanellakopoulos2, V. Kocman9, M. Kozak3, M. Madurga Flores6, G. Neyens1,2, S. Pallada, J.
Plavec9, K. Szutkowski3, M. Walczak10, F. Wienholtz, J. Wolak3, X.F. Yang11, D. Zakoucky12 Interaction of Na+ ions with DNA G-quadruplex structures studied directlywith Na beta-NMR spectroscopy published pages: , ISSN: , DOI: |
Addendum to P-521 to the ISOLDE and Neutron Time-of-Flight Commit CERN-INTC-2018-019 / INTC-P-521 | 2019-10-07 |
2018 |
W. Gins, R. Harding, M. Baranowski, M. L. Bissell, M. Kowalska, G.
Neyens, S. Pallada, N. Severijns, Ph. Velten, M. Walczak, F. Wienholtz, Z. Y. Xu, X. F.
Yang, D. Zakoucky The setup for laser spin-polarization at VITO-ISOLDE published pages: , ISSN: , DOI: |
To be submitted to: Nuclear Instruments and Methods in Physics A | 2019-10-07 |
2018 |
S. Pallada, for IS645 First β-NMR experiments with liquids at VITO published pages: 23, ISSN: , DOI: |
ISOLDE Newsletter 2018 | 2019-10-07 |
2017 |
M Kowalska, P Aschenbrenner, M Baranowski, M L Bissell, W Gins, R D Harding, H Heylen, G Neyens, S Pallada, N Severijns, Ph Velten, M Walczak, F Wienholtz, Z Y Xu, X F Yang, D Zakoucky New laser polarization line at the ISOLDE facility published pages: 84005, ISSN: 0954-3899, DOI: 10.1088/1361-6471/aa77d7 |
Journal of Physics G: Nuclear and Particle Physics 44/8 | 2019-10-07 |
2017 |
Attila Jancso, Joao G Correia, Alexander Gottberg, Juliana Schell, Monika Stachura, Dániel Szunyogh, Stavroula Pallada, Doru C Lupascu, Magdalena Kowalska, Lars Hemmingsen TDPAC and β -NMR applications in chemistry and biochemistry published pages: 64003, ISSN: 0954-3899, DOI: 10.1088/1361-6471/aa666b |
Journal of Physics G: Nuclear and Particle Physics 44/6 | 2019-10-07 |
2018 |
W. Gins, R. D. Harding, M. Baranowski, M. L. Bissell, R. F. Garcia Ruiz, M. Kowalska, G.
Neyens, S. Pallada, N. Severijns, Ph. Velten, F. Wienholtz, Z. Y. Xu, X. F. Yang, D.
Zakoucky A new beamline for laser spin-polarization at ISOLDE published pages: , ISSN: 0168-9002, DOI: |
Nuclear Instruments and Methods A | 2019-10-07 |
2018 |
M. Kowalska, V. Araujo Escalona, M. Baranowski3, J. Croese1,4, L. Cerato4, M. Bissell4, W. Gins2, F. Gustafsson2, R. Harding, L. Hemmingsen8, H. Heylen1, F. Hofmann, A. Kanellakopoulos, V. Kocman, M. Kozak, M. Madurga Flores, G. Neyens, S. Pallada, J. Plavec9, K. Szutkowski3, M. Walczak10, F. Wienholtz1, J. Wolak3, X.F. Yang11, D. Zakoucky1 Interaction of Na+ ions with DNA G-quadruplex structures studied directly with Na beta-NMR spectroscopy published pages: , ISSN: , DOI: |
CERN INTC Addendum to Proposal | 2019-10-07 |
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