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VPH-CaSE SIGNED

VPH-Cardiovascular Simulation and Experimentation for Personalised Medical Devices

Total Cost €

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EC-Contrib. €

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Partnership

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 VPH-CaSE project word cloud

Explore the words cloud of the VPH-CaSE project. It provides you a very rough idea of what is the project "VPH-CaSE" about.

scenarios    truly    combine    individual    presented    medicine    innovation    translation    tissue    quality    breadth    assurance    experts    beneficiaries    intervention    foundations    image    experimentation    faced    building    ultimate    technological    expertise    sme    tangible    engage    sectors    position    simulation    competitive    scientific    virtual    life    cardiac    acceptance    physiological    sectoral    clinic    outputs    equipping    clusters    leverage    training    personalised    edge    diagnosis    cutting    delivers    haemodynamics    function    environment    secondments    medical    nine    clinical    tight    innovative    disciplinary    inclusion    strategic    enviable    postgraduate    recruited    domain    skills    underpinned    translational    core    14    vph    exchange    integration    biomedical    directed    healthcare    pathology    designed    informed    skill    themselves    accelerating    cardiovascular    bias    industry    vision    benefits    human    esrs    career    collaborative    industrial    academic    eg    scientists    imaging   

Project "VPH-CaSE" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF SHEFFIELD 

Organization address
address: FIRTH COURT WESTERN BANK
city: SHEFFIELD
postcode: S10 2TN
website: www.shef.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website http://www.vph-case.eu
 Total cost 3˙700˙187 €
 EC max contribution 3˙700˙187 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2014
 Funding Scheme MSCA-ITN-ETN
 Starting year 2015
 Duration (year-month-day) from 2015-01-01   to  2018-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF SHEFFIELD UK (SHEFFIELD) coordinator 546˙575.00
2    UNIVERSITY COLLEGE LONDON UK (LONDON) participant 546˙575.00
3    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) participant 525˙751.00
4    POLITECNICO DI MILANO IT (MILANO) participant 516˙122.00
5    TECHNISCHE UNIVERSITEIT EINDHOVEN NL (EINDHOVEN) participant 510˙748.00
6    LEEDS TEST OBJECTS LIMITED UK (ROECLIFFE YORK) participant 273˙287.00
7    ANSYS FRANCE SAS FR (MONTIGNY LE BRETONNEUX) participant 262˙875.00
8    THERENVA FR (RENNES) participant 262˙875.00
9    LIFETEC GROUP BV NL (EINDHOVEN) participant 255˙374.00
10    CENTRE HOSPITALIER UNIVERSITAIRE DE RENNES FR (RENNES CEDEX 9) partner 0.00
11    ESAOTE EUROPE B.V. NL (MAASTRICHT) partner 0.00
12    Medtronic Invatec IT (Roncadelle) partner 0.00
13    SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST UK (SHEFFIELD) partner 0.00
14    Siemens FR (Saint Denis) partner 0.00
15    Sorin Group IT (Milano) partner 0.00
16    STICHTING CATHARINA ZIEKENHUIS NL (EINDHOVEN) partner 0.00
17    UNIVERSITE LAVAL CA (QUEBEC) partner 0.00
18    University Hospital, St Etienne FR (St Etienne) partner 0.00
19    University of Szeged US (CAMBRIDGE) partner 0.00

Map

 Project objective

VPH-CaSE is focused on state-of-the-art developments in personalised cardiovascular support, underpinned by simulation and experimentation, building on the foundations of the Virtual Physiological Human (VPH) Initiative. The Individual Research Projects of 14 ESRs provide knowledge exchange across three research clusters (i) Cardiac tissue function and cardiac support (ii) Cardiovascular haemodynamics - pathology and intervention (iii) Image-based diagnosis and imaging quality assurance. The work will be directed by the needs of industrial and clinical Beneficiaries and Partners, providing a truly multi-disciplinary, multi-sectoral environment for the ESRs. This will combine the expertise of nine core Beneficiaries (5 academic, 4 industrial) and 10 Partners (5 clinical, 4 industrial, 1 academic) to provide scientific support, secondments and training. VPH-CaSE will foster the development of ESRs within a collaborative environment. The recruited researchers will find themselves in an enviable position to leverage the expertise of a strategic sector of the European medical devices/simulation industry and engage with the issues faced by clinical experts in the domain of cardiac medicine and cardiovascular support. Their postgraduate studies will be informed by a translational bias that delivers a competitive skill-set, equipping them to address the challenges presented by a career at the cutting edge of technological innovation in healthcare delivery. The inclusion of a technology translation SME within the consortium is designed to promote the delivery of novel, tangible research outputs, providing benefits to a breadth of European sectors (eg. biomedical, clinical, VPH). The ultimate vision is the production of VPH-capable scientists with experience of tight integration of academic/industrial/clinical areas, able to apply their skills to real life scenarios, accelerating the acceptance of innovative and effective healthcare in the clinic.

 Deliverables

List of deliverables.
3rd year report WP2 Documents, reports 2019-06-19 15:19:11
3rd year report WP4 Documents, reports 2019-06-19 15:19:11
3rd year report WP3 Documents, reports 2019-06-19 15:19:11
Exposure of project outcomes Other 2019-06-19 15:19:11
Report on TA5 Documents, reports 2019-06-19 15:19:11
Report on TA1 Documents, reports 2019-06-19 15:19:09
Skills requirements Documents, reports 2019-06-19 15:19:09
Report on TA3 Documents, reports 2019-06-19 15:19:09
1st year report WP2 Documents, reports 2019-06-19 15:19:09
Supervisory Board Documents, reports 2019-06-19 15:19:09
1st year report WP4 Documents, reports 2019-06-19 15:19:08
Report on TA2 Documents, reports 2019-06-19 15:19:09
Report on TA4 Documents, reports 2019-06-19 15:19:09
1st year report WP3 Documents, reports 2019-06-19 15:19:08

Take a look to the deliverables list in detail:  detailed list of VPH-CaSE deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Paolo Ferraiuoli, Benjamin Kappler, Sjoerd van Tuijl, Marco Stijnen, Bas A.J.M. de Mol, John W. Fenner, Andrew J. Narracott
Full-field analysis of epicardial strain in an in vitro porcine heart platform
published pages: 294-300, ISSN: 1751-6161, DOI: 10.1016/j.jmbbm.2018.11.025
Journal of the Mechanical Behavior of Biomedical Materials 91 2019-06-19
2017 Paolo Ferraiuoli, Jonathan Taylor, Emily Martin, John Fenner, Andrew Narracott
The Accuracy of 3D Optical Reconstruction and Additive Manufacturing Processes in Reproducing Detailed Subject-Specific Anatomy
published pages: 45, ISSN: 2313-433X, DOI: 10.3390/jimaging3040045
Journal of Imaging 3/4 2019-06-19
2017 Mirko Bonfanti, Stavroula Balabani, John P. Greenwood, Sapna Puppala, Shervanthi Homer-Vanniasinkam, Vanessa Díaz-Zuccarini
Computational tools for clinical support: a multi-scale compliant model for haemodynamic simulations in an aortic dissection based on multi-modal imaging data
published pages: 20170632, ISSN: 1742-5689, DOI: 10.1098/rsif.2017.0632
Journal of The Royal Society Interface 14/136 2019-06-19
2018 Carlos A. Ledezma, Benjamin Kappler, Veronique Meijborg, Bas Boukens, Marco Stijnen, P. J. Tan, Vanessa Díaz-Zuccarini
Bridging Organ- and Cellular-Level Behavior in Ex Vivo Experimental Platforms Using Populations of Models of Cardiac Electrophysiology
published pages: 41003, ISSN: 2572-7958, DOI: 10.1115/1.4040589
Journal of Engineering and Science in Medical Diagnostics and Therapy 1/4 2019-06-19
2019 Marco Bologna, Susanna Migliori, Eros Montin, Rajiv Rampat, Gabriele Dubini, Francesco Migliavacca, Luca Mainardi, Claudio Chiastra
Automatic segmentation of optical coherence tomography pullbacks of coronary arteries treated with bioresorbable vascular scaffolds: Application to hemodynamics modeling
published pages: e0213603, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0213603
PLOS ONE 14/3 2019-06-19
2018 Claudio Chiastra, Susanna Migliori, Francesco Burzotta, Gabriele Dubini, Francesco Migliavacca
Patient-Specific Modeling of Stented Coronary Arteries Reconstructed from Optical Coherence Tomography: Towards a Widespread Clinical Use of Fluid Dynamics Analyses
published pages: 156-172, ISSN: 1937-5387, DOI: 10.1007/s12265-017-9777-6
Journal of Cardiovascular Translational Research 11/2 2019-06-19
2017 Claudio Chiastra, Eros Montin, Marco Bologna, Susanna Migliori, Cristina Aurigemma, Francesco Burzotta, Simona Celi, Gabriele Dubini, Francesco Migliavacca, Luca Mainardi
Reconstruction of stented coronary arteries from optical coherence tomography images: Feasibility, validation, and repeatability of a segmentation method
published pages: e0177495, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0177495
PLOS ONE 12/6 2019-06-19
2017 Susanna Migliori, Claudio Chiastra, Marco Bologna, Eros Montin, Gabriele Dubini, Cristina Aurigemma, Roberto Fedele, Francesco Burzotta, Luca Mainardi, Francesco Migliavacca
A framework for computational fluid dynamic analyses of patient-specific stented coronary arteries from optical coherence tomography images
published pages: 105-116, ISSN: 1350-4533, DOI: 10.1016/j.medengphy.2017.06.027
Medical Engineering & Physics 47 2019-06-19
2018 Susanna Migliori, Rajiv Rampat, Marco Bologna, Eros Montin, Francesco Burzotta, David Hildick-Smith, Gabriele Dubini, Luca Mainardi, Francesco Migliavacca, James Cockburn, Claudio Chiastra
A Patient-Specific Study Investigating the Relation between Coronary Hemodynamics and Neo-Intimal Thickening after Bifurcation Stenting with a Polymeric Bioresorbable Scaffold
published pages: 1510, ISSN: 2076-3417, DOI: 10.3390/app8091510
Applied Sciences 8/9 2019-06-19
2018 Benjamin Kappler
Optical Strain Measurements in a Passive Heart Simulator Loaded with different haemodynamic conditions
published pages: , ISSN: , DOI:
Researchers’ Conference “Frontiers of Simulation and Experimentation for Personalised Cardiovascular Management and Treatment 2018 2019-06-19
2018 Benjamin Kappler
Ex vivo cardiac physiology of isolated hemoperfused hearts - the need for dialysis
published pages: , ISSN: , DOI:
ESAO Winter School 2018 2019-06-19
2018 Allard van der Wal, Bas de Mol
Feasibility of mapping and cannulation of the porcine epicardial lymphatic system for sampling and decompression in heart failure research
published pages: 105-112, ISSN: 2424-810X, DOI: 10.18053/jctres.04.201802.002
Journal of Clinical and Translational Research 4(2) 2019-06-19
2019 Paolo Ferraiuoli, Benjamin Kappler, Sjoerd van Tuijl, Marco Stijnen, Bas A.J.M. de Mol, John W. Fenner, Andrew J. Narracott
Full-field analysis of epicardial strain in an in vitro porcine heart platform
published pages: 294-300, ISSN: 1751-6161, DOI: 10.1016/j.jmbbm.2018.11.025
Journal of the Mechanical Behavior of Biomedical Materials 91 2019-06-19
2018 Benjamin Kappler
Prediction of post-storage cardiac function
published pages: , ISSN: , DOI:
XLV Annual ESAO Congress 2018 2019-06-19
2018 Benjamin Kappler
Biochemical changes in an ex vivo hemoperfused porcine heart model
published pages: , ISSN: , DOI:
Young ESAO Congress 2018 2019-06-19
2017 Ferrari, S. and Ambrogio, S., and Walker, A. and Verma, P. and Narracott, A.J. and Wilkinson, I. and Fenner, J.W.
The Ring Vortex: concepts for a novel complex flow phantom for medical imaging
published pages: , ISSN: 2164-2788, DOI:
Open Journal of Medical Imaging 2017 2017 2019-06-19
2016 Gerardo Kenny Rumindo, Jacques Ohayon, Magalie Viallon-Croisille, Matthias Stuber, Pierre Croisille, Patrick Clarysse
Comparison of different strain-based parameters to identify human left ventricular myocardial infarct: a three-dimensional finite element study
published pages: , ISSN: , DOI:
2016 Int. Symposium on Computer Methods in Biomechanics and Biomedical Engineering 20 - 22 September 2016 2019-06-19
2016 S. Migliori, C. Chiastra, M. Bologna, E. Montin, C. Aurigemma, C. Credi, R. Fedele, M. Levi, F. Burzotta, L. Mainardi and F. Migliavacca
A robust OCT-based reconstruction of coronary bifurcation.
published pages: , ISSN: , DOI:
2019-06-19
2017 P.Ferraiuoli, JW Fenner, AJ Narracott
Uncertainty of 3D-DIC in cardiac strain measurements using numerically deformed stereo images
published pages: , ISSN: , DOI:
iDICs Conference 2017 iDICs Conference 2017 2019-06-19
2017 Paolo Ferraiuoli, John W. Fenner, Andrew J. Narracott
Analysis of speckle pattern quality and uncertainty for cardiac strain measurements using 3D digital image correlation
published pages: 883-892, ISSN: , DOI: 10.1007/978-3-319-68195-5_96
VipIMAGE 2017 Conference VipIMAGE 2017 Conference 2019-06-19
2017 Simone Ferrari, Simone Ambrogio, Adrian Walker, Prashant Verma, Andrew J Narracott, Iain Wilkinson John W Fenner
The ring vortex: concepts for a novel complex flow phantom for medical imaging
published pages: , ISSN: 2164-2796, DOI:
Open Journal of Medical Imaging (Mar 17) Open Journal of Medical Imaging 2019-06-19
2018 P.Ferraiuoli, JW Fenner, AJ Narracott
3D shape and full-field strain measurement in a coronary artery using 3D-DIC
published pages: , ISSN: , DOI:
12th International Conference on Advances in Experimental Mechanics 12th International Conference o 2019-06-19
2016 Gerardo Kenny Rumindo, Jacques Ohayon, Magalie Viallon, Mathias Stuber, Pierre Croisille, Patrick Clarysse
Comparison of different strain-based parameters to identify human left ventricular myocardial infarct during diastole: a 3D finite element study.
published pages: , ISSN: , DOI:
CMBBE, Tel Aviv, Israel. Sept 2016 CMBBE, Tel Aviv, Israel. Sept 2 2019-06-19
2017 Gerardo Kenny Rumindo, Nicolas Duchateau, Magalie Viallon, Pierre Croisille, Jacques Ohayon, Patrick Clarysse
Generation of a synthetic database of heart models to evaluate strain-based infarct detection algorithms
published pages: , ISSN: , DOI:
RITS, Lyon, France. March 2017 RITS, Lyon, France. March 2017 2019-06-19
2018 Mirko Bonfanti, Stavroula Balabani, Mona Alimohammadi, Obiekezie Agu, Shervanthi Homer-Vanniasinkam, Vanessa Díaz-Zuccarini
A simplified method to account for wall motion in patient-specific blood flow simulations of aortic dissection: Comparison with fluid-structure interaction
published pages: , ISSN: 1350-4533, DOI: 10.1016/j.medengphy.2018.04.014
Medical Engineering & Physics 2019-06-19
2017 Paolo Ferraiuoli, Jonathan Taylor, Emily Martin, John Fenner, Andrew Narracott
The Accuracy of 3D Optical Reconstruction and Additive Manufacturing Processes in Reproducing Detailed Subject-Specific Anatomy
published pages: 45, ISSN: 2313-433X, DOI: 10.3390/jimaging3040045
Journal of Imaging 3/4 2019-06-19
2018 Mirko Bonfanti, Stavroula Balabani, Mona Alimohammadi, Obiekezie Agu, Shervanthi Homer-Vanniasinkam, Vanessa Díaz-Zuccarini
A simplified method to account for wall motion in patient-specific blood flow simulations of aortic dissection: Comparison with fluid-structure interaction
published pages: , ISSN: 1350-4533, DOI: 10.1016/j.medengphy.2018.04.014
Medical Engineering & Physics 2019-06-19

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