Explore the words cloud of the MASSTRPLAN project. It provides you a very rough idea of what is the project "MASSTRPLAN" about.
The following table provides information about the project.
Coordinator |
ASTON UNIVERSITY
Organization address contact info |
Coordinator Country | United Kingdom [UK] |
Project website | http://www.masstrplan.org |
Total cost | 3˙545˙010 € |
EC max contribution | 3˙545˙010 € (100%) |
Programme |
1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers) |
Code Call | H2020-MSCA-ITN-2015 |
Funding Scheme | MSCA-ITN-ETN |
Starting year | 2015 |
Duration (year-month-day) | from 2015-10-01 to 2019-09-30 |
Take a look of project's partnership.
MASSTRPLAN will train the next generation of interdisciplinary research leaders in advanced molecular analytical techniques to detect oxidized phospholipids & proteins in biological & clinical samples, evaluate their biochemical roles in inflammation, and translate these findings to develop new diagnostic tools. Chronic inflammatory diseases such as diabetes, cardiovascular disease (CVD) & cancer are major causes of mortality and cost the EU economy dearly in healthcare and lost working time; CVD alone is estimated to be responsible for 47% of deaths and to cost the EU €196 billion a year. Scientists able to develop advanced analytical tools for detecting oxidative biomolecule modifications and assessing their contribution to cell dysfunction & disease are urgently needed. The objectives of MASSTRPLAN are to 1) train early stage researchers (ESRs) in advanced and novel chromatography, mass spectrometry, and complementary techniques including microscopy and bioinformatics to detect challenging heterogeneous biomolecule modifications and determine their functional effects; 2) give ESRs a broad perspective on relevance & mechanisms of oxidative modifications in pathophysiology and biotechnology; 3) enable ESRs trained in technology development to engage effectively with the clinical sector; and 4) train ESRs in translational and development skills to produce new protocols, materials and commercializable diagnostic tools. The ETN will achieve this by bringing together 10 beneficiaries and 15 partners from academic, industrial and healthcare organizations working in analytical, bioinformatic, biological, clinical & biotech fields to provide multidisciplinary, cross-sector training. Extensive mobility, industrial secondments and network-wide training will yield a cohort of analytical scientists with the unique theoretical, technological, and entrepreneurial skill set to yield new understanding of oxidative inflammatory disorders, leading to better tools and therapies.
Joint Public Engagement Event | Other | 2020-03-13 11:18:19 |
Special Issue on Lipoxidation Targets | Documents, reports | 2020-03-13 11:18:27 |
Annual Management Reports | Documents, reports | 2020-03-13 11:18:21 |
Network Summer School 2 | Other | 2020-03-13 11:18:20 |
Database of (lip)oxPTM Fragmentation | Other | 2020-03-13 11:18:27 |
Special Issue on Novel MS Methodology | Documents, reports | 2020-03-13 11:18:27 |
Bioinformatics Tool for oxPLs | Demonstrators, pilots, prototypes | 2020-03-13 11:18:26 |
Joint Training Certificates Awarded | Documents, reports | 2020-03-13 11:18:20 |
All ESR projects completed and reports submitted | Documents, reports | 2020-03-13 11:18:26 |
1st publication All ESRs | Documents, reports | 2020-03-13 11:18:25 |
Database of (lip)oxidation targets | Other | 2020-03-13 11:18:27 |
Final Technical Training Reports | Documents, reports | 2020-03-13 11:18:26 |
Open Conference | Other | 2020-03-13 11:18:24 |
Protocols for novel chemical labeling | Demonstrators, pilots, prototypes | 2020-03-13 11:18:25 |
Set of LC-MS Protocols for ox biomols | Demonstrators, pilots, prototypes | 2020-03-13 11:18:27 |
Technical Training Reports | Documents, reports | 2019-07-09 19:55:41 |
Project Website | Websites, patent fillings, videos etc. | 2019-07-09 19:55:40 |
Bioinformatics Tool for oxPTMs | Demonstrators, pilots, prototypes | 2019-07-09 19:55:41 |
Network Summer School 1 | Other | 2019-07-09 19:55:41 |
Mutant Protein Constructs | Other | 2019-07-09 19:55:41 |
Data Management Plan Agreed | Documents, reports | 2019-07-09 19:55:40 |
ESR Recruitment | Other | 2019-07-09 19:55:41 |
Database of oxPL/NO2PL Fragmentation | Other | 2019-07-09 19:55:41 |
Take a look to the deliverables list in detail: detailed list of MASSTRPLAN deliverables.
year | authors and title | journal | last update |
---|---|---|---|
2018 |
M. Rosário Domingues, Ana Campos, Simone Colombo, Tânia Melo, Pedro Domingues Radical induced oxidation of di-oleoyl phosphatidylserine using mass spectrometry revealed preferential oxydation of Sn-2 oleoyl chain published pages: S118, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2018.04.390 |
Free Radical Biology and Medicine 120 | 2019-12-16 |
2018 |
Javier-Fernando Montero-Bullón, Tânia Melo, M Rosário M Domingues, Pedro Domingues Study of covalent adduction of nitrated phospholipids to peptides using tandem mass spectrometry in different instruments published pages: S121, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2018.04.399 |
Free Radical Biology and Medicine 120 | 2019-12-16 |
2019 |
Elisabete Maciel, Bruno M. Neves, João Martins, Simone Colombo, Maria Teresa Cruz, Pedro Domingues, M. Rosário M. Domingues Oxidized phosphatidylserine mitigates LPS-triggered macrophage inflammatory status through modulation of JNK and NF-kB signaling cascades published pages: 30-38, ISSN: 0898-6568, DOI: 10.1016/j.cellsig.2019.04.015 |
Cellular Signalling 61 | 2019-12-16 |
2019 |
Gabriele Cruciani, Pedro Domingues, Maria Fedorova, Francesco Galli, Corinne M. Spickett Redox lipidomics and adductomics - Advanced analytical strategies to study oxidized lipids and lipid-protein adducts published pages: 1-5, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2019.07.027 |
Free Radical Biology and Medicine 144 | 2019-12-16 |
2019 |
Mike Lange, Zhixu Ni, Angela Criscuolo, Maria Fedorova Liquid Chromatography Techniques in Lipidomics Research published pages: 77-100, ISSN: 0009-5893, DOI: 10.1007/s10337-018-3656-4 |
Chromatographia 82/1 | 2019-12-16 |
2019 |
Florian Füssl, Angela Criscuolo, Ken Cook, Kai Scheffler, Jonathan Bones Cracking Proteoform Complexity of Ovalbumin with Anion-Exchange Chromatography–High-Resolution Mass Spectrometry under Native Conditions published pages: 3689-3702, ISSN: 1535-3893, DOI: 10.1021/acs.jproteome.9b00375 |
Journal of Proteome Research 18/10 | 2019-11-26 |
2019 |
Isabel Campos-Pinto, LucÃa Méndez, James Schouten, John Wilkins, Maria Fedorova, Andrew R. Pitt, Paul Davis, Corinne M. Spickett Epitope mapping and characterization of 4-hydroxy-2-nonenal modified-human serum albumin using two different polyclonal antibodies published pages: 234-244, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2019.05.008 |
Free Radical Biology and Medicine 144 | 2019-11-26 |
2019 |
Zhixu Ni, Bebiana C. Sousa, Simone Colombo, Catarina B. Afonso, Tania Melo, Andrew R. Pitt, Corinne M. Spickett, Pedro Domingues, M. Rosário Domingues, Maria Fedorova, Angela Criscuolo Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS published pages: 156-166, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2019.06.013 |
Free Radical Biology and Medicine 144 | 2019-11-26 |
2018 |
Javier-Fernando Montero-Bullon, Tânia Melo, Maria Rosário Domingues, Pedro Domingues Characterization of Nitrophospholipid-Peptide Covalent Adducts by Electrospray Tandem Mass Spectrometry: A First Screening Analysis Using Different Instrumental Platforms published pages: 1800101, ISSN: 1438-7697, DOI: 10.1002/ejlt.201800101 |
European Journal of Lipid Science and Technology 120/12 | 2019-11-26 |
2019 |
Zhixu Ni, Laura Goracci, Gabriele Cruciani, Maria Fedorova Computational solutions in redox lipidomics – Current strategies and future perspectives published pages: 110-123, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2019.04.027 |
Free Radical Biology and Medicine 144 | 2019-11-26 |
2019 |
Dolores Pérez-Sala, Rosário Domingues Lipoxidation targets: From basic mechanisms to pathophysiology published pages: 101208, ISSN: 2213-2317, DOI: 10.1016/j.redox.2019.101208 |
Redox Biology 23 | 2019-11-26 |
2017 |
Javier Egea, Isabel Fabregat, Yves M. Frapart, Pietro Ghezzi, Agnes Görlach, Thomas Kietzmann, Kateryna Kubaichuk, Ulla G. Knaus, Manuela G. Lopez, Gloria Olaso-Gonzalez, Andreas Petry, Rainer Schulz, Jose Vina, Paul Winyard, Kahina Abbas, Opeyemi S. Ademowo, Catarina B. Afonso, Ioanna Andreadou, Haike Antelmann, Fernando Antunes, Mutay Aslan, Markus M. Bachschmid, Rui M. Barbosa, Vsevolod Belous European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) published pages: 94-162, ISSN: 2213-2317, DOI: 10.1016/j.redox.2017.05.007 |
Redox Biology 13 | 2019-11-26 |
2019 |
Javier-Fernando Montero-Bullon, Tânia Melo, Rita Ferreira, Ana Isabel Padrão, Paula A. Oliveira, M. Rosário M. Domingues, Pedro Domingues Exercise training counteracts urothelial carcinoma-induced alterations in skeletal muscle mitochondria phospholipidome in an animal model published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-019-49010-6 |
Scientific Reports 9/1 | 2019-11-26 |
2019 |
Sofia Duarte, Tânia Melo, Rosário Domingues, Juan de Dios Alché, Dolores Pérez-Sala Insight into the cellular effects of nitrated phospholipids: Evidence for pleiotropic mechanisms of action published pages: 192-202, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2019.06.003 |
Free Radical Biology and Medicine 144 | 2019-11-26 |
2019 |
Bebiana C. Sousa, Tanzim Ahmed, William L. Dann, Jed Ashman, Alexandre Guy, Thierry Durand, Andrew R. Pitt, Corinne M. Spickett Short-chain lipid peroxidation products form covalent adducts with pyruvate kinase and inhibit its activity in vitro and in breast cancer cells published pages: 223-233, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2019.05.028 |
Free Radical Biology and Medicine 144 | 2019-11-26 |
2018 |
Andreia Mónico, Sofia Duarte, Maria A. Pajares, Dolores Pérez-Sala Effects of oxidants and electrophiles on vimentin assembly published pages: S69, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2018.04.227 |
Free Radical Biology and Medicine 120 | 2019-11-26 |
2019 |
Tânia Melo, Javier-Fernando Montero-Bullón, Pedro Domingues, M. Rosário Domingues Discovery of bioactive nitrated lipids and nitro-lipid-protein adducts using mass spectrometry-based approaches published pages: 101106, ISSN: 2213-2317, DOI: 10.1016/j.redox.2019.101106 |
Redox Biology 23 | 2019-11-26 |
2019 |
Leanne C. Nye, Jonathan P. Williams, Nyasha C. Munjoma, Marine P.M. Letertre, Muireann Coen, Robbin Bouwmeester, Lennart Martens, Jonathan R. Swann, Jeremy K. Nicholson, Robert S. Plumb, Michael McCullagh, Lee A. Gethings, Steven Lai, James I. Langridge, Johannes P.C. Vissers, Ian D. Wilson A comparison of collision cross section values obtained via travelling wave ion mobility-mass spectrometry and ultra high performance liquid chromatography-ion mobility-mass spectrometry: Application to the characterisation of metabolites in rat urine published pages: 386-396, ISSN: 0021-9673, DOI: 10.1016/j.chroma.2019.06.056 |
Journal of Chromatography A 1602 | 2019-11-11 |
2019 |
Ana S C Silva, Robbin Bouwmeester, Lennart Martens, Sven Degroeve Accurate peptide fragmentation predictions allow data driven approaches to replace and improve upon proteomics search engine scoring functions published pages: , ISSN: 1367-4803, DOI: 10.1093/bioinformatics/btz383 |
Bioinformatics | 2019-11-11 |
2019 |
Sofia Duarte, Ãlvaro Viedma-Poyatos, Elena Navarro-Carrasco, Alma E. MartÃnez, MarÃa A. Pajares, Dolores Pérez-Sala Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-019-12029-4 |
Nature Communications 10/1 | 2019-10-29 |
2019 |
Dolores Pérez-Sala, Rosário Domingues Lipoxidation targets: From basic mechanisms to pathophysiology published pages: 101208, ISSN: 2213-2317, DOI: 10.1016/j.redox.2019.101208 |
Redox Biology | 2019-10-29 |
2019 |
Alma Martinez Fernandez, Luca Regazzoni, Maura Brioschi, Erica Gianazza, Piergiuseppe Agostoni, Giancarlo Aldini, Cristina Banfi Pro-oxidant and pro-inflammatory effects of glycated albumin on cardiomyocytes published pages: , ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2019.06.023 |
Free Radical Biology and Medicine | 2019-10-03 |
2018 |
Marco Mol, Genny Degani, Crescenzo Coppa, Giovanna Baron, Laura Popolo, Marina Carini, Giancarlo Aldini, Giulio Vistoli, Alessandra Altomare Advanced lipoxidation end products (ALEs) as RAGE binders: Mass spectrometric and computational studies to explain the reasons why published pages: 101083, ISSN: 2213-2317, DOI: 10.1016/j.redox.2018.101083 |
Redox Biology | 2019-10-03 |
2017 |
Bebiana C. Sousa, Andrew R. Pitt, Corinne M. Spickett Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds published pages: 294-308, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2017.02.003 |
Free Radical Biology and Medicine 111 | 2019-07-09 |
2018 |
Ãlvaro Viedma-Poyatos, Yolanda de Pablo, Milos Pekny, Dolores Pérez-Sala The cysteine residue of glial fibrillary acidic protein is a critical target for lipoxidation and required for efficient network organization published pages: 380-394, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2018.04.007 |
Free Radical Biology and Medicine 120 | 2019-07-09 |
2018 |
Simone Colombo, Carmen MartÃn-Sierra, Tânia Melo, Paula Laranjeira, Artur Paiva, Pedro Domingues, M. Rosário Domingues Modulation of the inflammatory response of immune cells in human peripheral blood by oxidized arachidonoyl aminophospholipids published pages: 64-71, ISSN: 0003-9861, DOI: 10.1016/j.abb.2018.10.003 |
Archives of Biochemistry and Biophysics 660 | 2019-08-05 |
2019 |
Andreia Mónico, Sofia Duarte, MarÃa A. Pajares, Dolores Pérez-Sala Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics published pages: 101098, ISSN: 2213-2317, DOI: 10.1016/j.redox.2019.101098 |
Redox Biology | 2019-08-05 |
2019 |
Carmen MartÃn-Sierra, Ricardo Martins, Paula Laranjeira, A. Margarida Abrantes, R. Caetano Oliveira, J. Guilherme Tralhão, M. Filomena Botelho, Emanuel Furtado, Rosário Domingues, Artur Paiva Functional Impairment of Circulating FcεRI + Monocytes and Myeloid Dendritic Cells in Hepatocellular Carcinoma and Cholangiocarcinoma Patients published pages: , ISSN: 1552-4949, DOI: 10.1002/cyto.b.21777 |
Cytometry Part B: Clinical Cytometry | 2019-08-05 |
2019 |
Silvia Zorrilla, Andreia Mónico, Sofia Duarte, Germán Rivas, Dolores Pérez-Sala, MarÃa A. Pajares Integrated approaches to unravel the impact of protein lipoxidation on macromolecular interactions published pages: , ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2019.04.011 |
Free Radical Biology and Medicine | 2019-08-05 |
2019 |
Giulia Coliva, Sofia Duarte, Dolores Pérez-Sala, Maria Fedorova Impact of inhibition of the autophagy-lysosomal pathway on biomolecules carbonylation and proteome regulation in rat cardiac cells published pages: 101123, ISSN: 2213-2317, DOI: 10.1016/j.redox.2019.101123 |
Redox Biology | 2019-08-05 |
2018 |
Julita Pietrzak, Corinne M. Spickett, Tomasz Płoszaj, László Virág, Agnieszka Robaszkiewicz PARP1 promoter links cell cycle progression with adaptation to oxidative environment published pages: 1-5, ISSN: 2213-2317, DOI: 10.1016/j.redox.2018.05.017 |
Redox Biology 18 | 2019-07-09 |
2018 |
Simone Colombo, Tânia Melo, Marta MartÃnez-López, M. Jesús Carrasco, M. Rosário Domingues, Dolores Pérez-Sala, Pedro Domingues Phospholipidome of endothelial cells shows a different adaptation response upon oxidative, glycative and lipoxidative stress published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-30695-0 |
Scientific Reports 8/1 | 2019-07-09 |
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