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MAST4HEALTH SIGNED

Mastiha treatment for healthy obese with NAFLD diagnosis (MAST4HEALTH).

Total Cost €

EC-Contrib. €

Partnership

Views

Outcomes and
results

MAST4HEALTH project word cloud

Explore the words cloud of the MAST4HEALTH project. It provides you a very rough idea of what is the project "MAST4HEALTH" about.

interactions shown explore supplement strategy cooperation lipid diabetes antioxidant parallel interaction academic bioactive gene disease correlate complications patients mastiha 50 mellitus effect designed approximately phytochemicals plants post personalized substances intestinal multidisciplinary populations genetic mast4health trial western vegetables nafld fruits pharmacological microbiota metabolomic double possess randomized anti obese sectors diet train students pharmacologic survey intervention therapies phd greece markers clinical 76 epigenetic inflammatory lowering blind natural limitations nash effectiveness profiles diabetics dietary obesity arm laboratory efforts meanwhile multicenter exploring treatment placebo

Project "MAST4HEALTH" data sheet

The following table provides information about the project.

Coordinator	CHAROKOPEIO PANEPISTIMIO Organization address address: ELEFTHERIOU VENIZELOU 70 city: ATHINA postcode: 17671 website: www.hua.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Greece [EL]
Project website	http://www.mast4health.eu/en/
Total cost	2˙124˙000 €
EC max contribution	2˙124˙000 € (100%)
Programme	1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
Code Call	H2020-MSCA-RISE-2015
Funding Scheme	MSCA-RISE
Starting year	2016
Duration (year-month-day)	from 2016-03-01 to 2020-02-29

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	CHAROKOPEIO PANEPISTIMIO CHAROKOPEIO PANEPISTIMIO Organization address address: ELEFTHERIOU VENIZELOU 70 city: ATHINA postcode: 17671 website: www.hua.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (ATHINA)	coordinator	441˙000.00
2	ENOSIS MASTICHOPARAGOGON CHIOU ENOSIS MASTICHOPARAGOGON CHIOU Organization address address: 1 K. MONOMACHOU ST city: CHIOS postcode: 82100 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (CHIOS)	participant	297˙000.00
3	QUEEN MARY UNIVERSITY OF LONDON QUEEN MARY UNIVERSITY OF LONDON Organization address address: 327 MILE END ROAD city: LONDON postcode: E1 4NS website: http://www.qmul.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	162˙000.00
4	BIOTECH VANA SL BIOTECH VANA SL Organization address address: CALLE CATEDRATICO AGUSTIN ESCARDINO 9, EDIFICIO 1.17, VIVERO PARC CIENTIFIC DE LA UNIVERSITAT DE VALENCIA city: PATERNA (VALENCIA) postcode: 46980 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (PATERNA (VALENCIA))	participant	157˙500.00
5	PERSPECTUM LTD PERSPECTUM LTD Organization address address: GEMINI ONE, 5520 JOHN SMITH DRIVE OXFORD BUSINESS PARK SOUTH city: OXFORD postcode: OX4 2LL website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (OXFORD)	participant	157˙500.00
6	Randox Laboratories Ltd Randox Laboratories Ltd Organization address address: Diamond Road 55 city: Crumlin postcode: BT29 4QY website: www.randox.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (Crumlin)	participant	153˙000.00
7	INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE Organization address address: RUE DE TOLBIAC 101 city: PARIS postcode: 75654 website: www.inserm.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	135˙000.00
8	CONSIGLIO NAZIONALE DELLE RICERCHE CONSIGLIO NAZIONALE DELLE RICERCHE Organization address address: PIAZZALE ALDO MORO 7 city: ROMA postcode: 185 website: www.cnr.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (ROMA)	participant	121˙500.00
9	FUNDACION PARA EL FOMENTO DE LA INVESTIGACION SANITARIA Y BIOMEDICA DE LA COMUNITAT VALENCIANA FUNDACION PARA EL FOMENTO DE LA INVESTIGACION SANITARIA Y BIOMEDICA DE LA COMUNITAT VALENCIANA Organization address address: CALLE MICER MASCO 31 city: VALENCIA postcode: 46010 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (VALENCIA)	participant	117˙000.00
10	MARASCIO FERNANDO MARASCIO FERNANDO Organization address address: VIA SANTA LOMENICA 57 city: CATANZARO postcode: 88100 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (CATANZARO)	participant	108˙000.00
11	Univerzitet u Novom Sadu - Medicinski fakultet Univerzitet u Novom Sadu - Medicinski fakultet Organization address address: Hajduk Veljkova Street 3 city: Novi Sad postcode: 21000 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	RS (Novi Sad)	participant	108˙000.00
12	SANOFI-AVENTIS DEUTSCHLAND GMBH SANOFI-AVENTIS DEUTSCHLAND GMBH Organization address address: BRUNINGSTRASSE 50 city: FRANKFURT AM MAIN postcode: 65929 website: www.sanofi.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (FRANKFURT AM MAIN)	participant	81˙000.00
13	UNIVERSITA DEGLI STUDI DI MILANO UNIVERSITA DEGLI STUDI DI MILANO Organization address address: Via Festa Del Perdono 7 city: MILANO postcode: 20122 website: www.unimi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	participant	63˙000.00
14	UNIVERZITET U ISTOCNOM SARAJEVU UNIVERZITET U ISTOCNOM SARAJEVU Organization address address: VUKA KARADZICA 30 city: ISTOCNO SARAJEVO postcode: 71123 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BA (ISTOCNO SARAJEVO)	participant	13˙500.00
15	FONDAZIONE IRCCS CA' GRANDA - OSPEDALE MAGGIORE POLICLINICO FONDAZIONE IRCCS CA' GRANDA - OSPEDALE MAGGIORE POLICLINICO Organization address address: VIA FRANCESCO SFORZA 28 city: MILANO postcode: 20122 website: www.policlinico.mi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	participant	9˙000.00

Map

Project objective

MAST4HEALTH is set on the concept of a multidisciplinary approach to assess a non-pharmacological intervention for managing NAFLD/NASH, one of the most common complications of obesity and diabetes mellitus in Western populations affecting approximately 50% of diabetics and 76% of obese patients. Because of limitations in current NAFLD treatment therapies, many new efforts focus on exploring non-pharmacologic means for managing the disease and in particular through dietary substances or bioactive phytochemicals in fruits, vegetables, and plants or their products. MAST4HEALTH aims at exploring the effect of Mastiha, a natural product of Greece which was recently shown to possess antioxidant/anti-inflammatory and lipid lowering properties. We designed a multicenter randomized double blind placebo controlled (parallel arm) clinical trial to test the effectiveness of Mastiha supplement as new non-pharmacologic strategy for NAFLD/NASH treatment. MAST4HEALTH will explore gene-diet interactions, more specifically the potential personalized activity of the Mastiha, and correlate genetic and epigenetic markers with metabolomic and intestinal microbiota profiles pre- and post-intervention. The effectiveness of the proposed intervention will be evaluated via clinical and laboratory markers of the disease. To this end, MAST4HEALTH will train a number of researchers and PhD students in multidisciplinary approaches of this survey. MAST4HEALTH is expected to build and enhance cooperation among partners meanwhile strengthening the interaction between our academic and non-academic sectors

Deliverables

List of deliverables.
Organization of all Meetings	Other	2020-03-11 12:59:20
Acceptance for publication of manuscripts	Documents, reports	2020-03-11 12:59:20
Abstract submission to conferences	Other	2020-03-11 12:59:20
E-newsletter publication	Websites, patent fillings, videos etc.	2020-03-11 12:59:20
Web page creation	Websites, patent fillings, videos etc.	2020-03-11 12:59:20
Progress report P1	Other	2020-03-11 12:59:20
Public engagement and outreach plan	Other	2020-03-11 12:59:20

Take a look to the deliverables list in detail: detailed list of MAST4HEALTH deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Aimo Kannt, Efstathia Papada, Claire Kammermeier, Giuseppe D\'Auria, Nuria JimÃ©nezâ€HernÃ¡ndez, Martin Stephan, Uwe Schwahn, Andreas Nygaard Madsen, Mette Viberg Ã˜stergaard, George Dedoussis, M. Pilar Francino Mastiha ( Pistacia lentiscus ) Improves Gut Microbiota Diversity, Hepatic Steatosis, and Disease Activity in a Biopsyâ€Confirmed Mouse Model of Advanced Nonâ€Alcoholic Steatohepatitis and Fibrosis published pages: 1900927, ISSN: 1613-4125, DOI: 10.1002/mnfr.201900927	Molecular Nutrition & Food Research 63/24	2020-03-11

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The information about "MAST4HEALTH" are provided by the European Opendata Portal: CORDIS opendata.