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MiCoBion SIGNED

Microbial Communities in Biomedical and Environmental Areas, and Systems Biology

Total Cost €

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EC-Contrib. €

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Partnership

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MiCoBion project word cloud

Explore the words cloud of the MiCoBion project. It provides you a very rough idea of what is the project "MiCoBion" about.

viromes twinning promotion viruses multiomics organization area pillars lectures biotechnology generate establishing reinforce environmental scientists center data big voluminous excellence seminars identification young leuven catholic diderot edge charles eukaryotic health innovative bioinformatics exchange laboratory complementary molecular updiderot communities capacity community limited tackle multidisciplinary paris added cuni biological biomedicine microbial biology biomarkers biocev pipeline drug scientist basic expertise environment profiling jacques monod bacterial weakness animal supervision human strength cutting innovation microbioms industries computation pathogens joint excellent scientific microbiology strengthen throughput transfer courses kul embl public implementing model ijm technologies discovery disease team competitiveness university participation datasets

Project "MiCoBion" data sheet

The following table provides information about the project.

Coordinator	UNIVERZITA KARLOVA Organization address address: OVOCNY TRH 560/5 city: PRAHA 1 postcode: 116 36 website: www.cuni.cz contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Czech Republic [CZ]
Total cost	998˙205 €
EC max contribution	998˙205 € (100%)
Programme	1. H2020-EU.4.b. (Twinning of research institutions)
Code Call	H2020-WIDESPREAD-05-2017-Twinning
Funding Scheme	CSA
Starting year	2018
Duration (year-month-day)	from 2018-09-01 to 2021-08-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERZITA KARLOVA UNIVERZITA KARLOVA Organization address address: OVOCNY TRH 560/5 city: PRAHA 1 postcode: 116 36 website: www.cuni.cz contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CZ (PRAHA 1)	coordinator	587˙156.00
2	EUROPEAN MOLECULAR BIOLOGY LABORATORY EUROPEAN MOLECULAR BIOLOGY LABORATORY Organization address address: Meyerhofstrasse 1 city: HEIDELBERG postcode: 69117 website: http://www.embl.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (HEIDELBERG)	participant	144˙068.00
3	UNIVERSITE DE PARIS UNIVERSITE DE PARIS Organization address address: 85 BD SAINT GERMAIN city: PARIS postcode: 75006 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	135˙730.00
4	KATHOLIEKE UNIVERSITEIT LEUVEN KATHOLIEKE UNIVERSITEIT LEUVEN Organization address address: OUDE MARKT 13 city: LEUVEN postcode: 3000 website: www.kuleuven.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LEUVEN)	participant	131˙250.00
5	UNIVERSITE PARIS DIDEROT - PARIS 7 UNIVERSITE PARIS DIDEROT - PARIS 7 Organization address address: RUE THOMAS MANN 5 city: PARIS postcode: 75205 website: www.univ-paris-diderot.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	0.00

Map

Project objective

'The main goal of the proposed project is to strengthen scientific excellence and innovation capacity at Charles University and its Biotechnology and Biomedicine Center (CUNI-BIOCEV) via collaboration with Catholic University of Leuven (KUL), European Molecular Biology Laboratory (EMBL), and University Paris Diderot-Institute Jacques Monod (UPDiderot-IJM) in the field of high throughput molecular profiling of biological systems that will foster innovative research of complex microbial communities and their impact on health and environment. This research area includes the analysis of viromes, eukaryotic and bacterial microbioms, and selected defined model microbial communities to tackle challenges such as discovery of new pathogens (viruses), identification of new biomarkers for disease, drug targets and their applications. The research of complex microbial communities is based on three pillars: excellent knowledge in microbiology, high throughput technologies that generate voluminous datasets, and computation of these 'big data'. Strength of CUNI is an excellent knowledge of microbial systems important for human and animal health, and environmental issues. Weakness is the research capacity in analysis of 'big data', limited experience in innovative research and technology transfer. Thus, twinning activities will be focused on promotion of knowledge and research capacity of a multidisciplinary team at CUNI in the defined area of bioinformatics, implementing cutting edge multiomics technologies, and establishing a pipeline from an excellent basic research to high value-added applications. Activities include exchange of scientists, joint supervision of young scientist, organization of seminars and lectures, participation in EMBL and CUNI courses, and dissemination in scientific community, industries and public. The project aim will be achieved via a complementary expertise of EU leading partners, which will reinforce an excellent research and competitiveness of CUNI.'

Publications

List of publications.
year	authors and title	journal	last update
2019	Tien Le, VojtÄ›ch Å½Ã¡rskÃ½, Eva NÃ½vltovÃ¡, Petr Rada, Karel Harant, Marie VancovÃ¡, ZdenÄ›k Verner, Ivan HrdÃ½, Jan Tachezy Anaerobic peroxisomes in Mastigamoeba balamuthi published pages: 201909755, ISSN: 0027-8424, DOI: 10.1073/pnas.1909755117	Proceedings of the National Academy of Sciences	2020-02-18
2019	Ivo Florin Scheiber, Jana PilÃ¡tovÃ¡, Ronald Malych, Eva Kotabova, MatyÃ¡Å¡ Krijt, Daniel Vyoral, Jan Mach, Thibaut LÃ©ger, Jean-Michel Camadro, OndÅ™ej PrÃ¡Å¡il, Emmanuel Lesuisse, Robert Sutak Copper and iron metabolism in Ostreococcus tauri â€“ the role of phytotransferrin, plastocyanin and a chloroplast copper-transporting ATPase published pages: 1657-1666, ISSN: 1756-5901, DOI: 10.1039/c9mt00078j	Metallomics 11/10	2020-02-18
2019	VÃ¡clav VopÃ¡lenskÃ½, Michal SÃ½kora, TomÃ¡Å¡ MaÅ¡ek, Martin PospÃÅ¡ek Messenger RNAs of Yeast Virus-Like Elements Contain Non-templated 5â€² Poly(A) Leaders, and Their Expression Is Independent of eIF4E and Pab1 published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2019.02366	Frontiers in Microbiology 10	2020-02-18
2016	Anna Karnkowska, VojtÄ›ch Vacek, Zuzana ZubÃ¡ÄovÃ¡, Sebastian C. Treitli, Romana PetrÅ¾elkovÃ¡, Laura Eme, LukÃ¡Å¡ NovÃ¡k, VojtÄ›ch Å½Ã¡rskÃ½, Lael D. Barlow, Emily K. Herman, Petr Soukal, MiluÅ¡e HroudovÃ¡, Pavel DoleÅ¾al, Courtney W. Stairs, Andrew J. Roger, Marek EliÃ¡Å¡, Joel B. Dacks, ÄŒestmÃr VlÄek, VladimÃr Hampl A Eukaryote without a Mitochondrial Organelle published pages: 1274-1284, ISSN: 0960-9822, DOI: 10.1016/j.cub.2016.03.053	Current Biology 26/10	2020-02-18
2015	Eva NÃ½vltovÃ¡, Courtney W. Stairs, Ivan HrdÃ½, Jakub RÃdl, Jan Mach, Jan PaÄes, Andrew J. Roger, Jan Tachezy Lateral Gene Transfer and Gene Duplication Played a Key Role in the Evolution of Mastigamoeba balamuthi Hydrogenosomes published pages: 1039-1055, ISSN: 0737-4038, DOI: 10.1093/molbev/msu408	Molecular Biology and Evolution 32/4	2020-02-18
2017	Lan-Feng Dong, Jaromira Kovarova, Martina Bajzikova, Ayenachew Bezawork-Geleta, David Svec, Berwini Endaya, Karishma Sachaphibulkij, Ana R Coelho, Natasa Sebkova, Anna Ruzickova, An S Tan, Katarina Kluckova, Kristyna Judasova, Katerina Zamecnikova, Zuzana Rychtarcikova, Vinod Gopalan, Ladislav Andera, Margarita Sobol, Bing Yan, Bijay Pattnaik, Naveen Bhatraju, Jaroslav Truksa, Pavel Stopka, Pavel Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells published pages: , ISSN: 2050-084X, DOI: 10.7554/eLife.22187	eLife 6	2020-02-18
2015	Anas Khawaja, Vaclav Vopalensky, Martin Pospisek Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function published pages: 211-224, ISSN: 1757-7004, DOI: 10.1002/wrna.1268	Wiley Interdisciplinary Reviews: RNA 6/2	2020-02-18
2015	Steven Sijmons, Kim Thys, Mirabeau Mbong Ngwese, Ellen Van Damme, Jan Dvorak, Marnix Van Loock, Guangdi Li, Ruth Tachezy, Laurent Busson, Jeroen Aerssens, Marc Van Ranst, Piet Maes High-Throughput Analysis of Human Cytomegalovirus Genome Diversity Highlights the Widespread Occurrence of Gene-Disrupting Mutations and Pervasive Recombination published pages: 7673-7695, ISSN: 0022-538X, DOI: 10.1128/JVI.00578-15	Journal of Virology 89/15	2020-02-18
2015	Joe Morrissey, Robert Sutak, Javier Paz-Yepes, Atsuko Tanaka, Ahmed Moustafa, Alaguraj Veluchamy, Yann Thomas, Hugo Botebol, FranÃ§ois-Yves Bouget, JeffreyÂ B. McQuaid, Leila Tirichine, AndrewÂ E. Allen, Emmanuel Lesuisse, Chris Bowler A Novel Protein, Ubiquitous in Marine Phytoplankton, Concentrates Iron at the Cell Surface and Facilitates Uptake published pages: 364-371, ISSN: 0960-9822, DOI: 10.1016/j.cub.2014.12.004	Current Biology 25/3	2020-02-18
2017	LuboÅ¡ Voleman, VladimÃra NajdrovÃ¡, Ãsgeir Ãstvaldsson, Pavla TÅ¯movÃ¡, Elin Einarsson, ZdenÄ›k Å vindrych, Guy M. Hagen, Jan Tachezy, Staffan G. SvÃ¤rd, Pavel DoleÅ¾al Giardia intestinalis mitosomes undergo synchronized fission but not fusion and are constitutively associated with the endoplasmic reticulum published pages: , ISSN: 1741-7007, DOI: 10.1186/s12915-017-0361-y	BMC Biology 15/1	2020-02-18
2016	Zdena PalkovÃ¡, LibuÅ¡e VÃ¡chovÃ¡ Yeast cell differentiation: Lessons from pathogenic and non-pathogenic yeasts published pages: 110-119, ISSN: 1084-9521, DOI: 10.1016/j.semcdb.2016.04.006	Seminars in Cell & Developmental Biology 57	2020-02-18
2017	Junie Hovsepian, Quentin DefenouillÃ¨re, VÃ©ronique AlbanÃ¨se, LibuÅ¡e VÃ¡chovÃ¡, Camille Garcia, Zdena PalkovÃ¡, SÃ©bastien LÃ©on Multilevel regulation of an Î±-arrestin by glucose depletion controls hexose transporter endocytosis published pages: 1811-1831, ISSN: 0021-9525, DOI: 10.1083/jcb.201610094	The Journal of Cell Biology 216/6	2020-02-18
2018	Phu Van Nguyen, Otakar HlavÃ¡Äek, Jana MarÅ¡ÃkovÃ¡, LibuÅ¡e VÃ¡chovÃ¡, Zdena PalkovÃ¡ Cyc8p and Tup1p transcription regulators antagonistically regulate Flo11p expression and complexity of yeast colony biofilms published pages: e1007495, ISSN: 1553-7404, DOI: 10.1371/journal.pgen.1007495	PLOS Genetics 14/7	2020-02-18

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