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Secreters SIGNED

A new generation of microbial expression hosts and tools for the production of biotherapeutics and high-value enzymes

Total Cost €

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EC-Contrib. €

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Partnership

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 Secreters project word cloud

Explore the words cloud of the Secreters project. It provides you a very rough idea of what is the project "Secreters" about.

redox    medicines    markets    team    patient    whereas    engage    recombinant    enzymes    diseases    premier    lower    innovations    biotherapeutic    chemistry    pichia    series    world    billion    disulphide    ranging    training    categories    treatment    combined    thrive    close    outreach    industry    proteins    responsible    beneficiaries    skills    express    daily    commitment    interdisciplinary    equip    producing    poised    intersectoral    trained    superbly    bonded    15    140    scientists    escherichia    enzyme    synthetic    secreters    innovation    train    difficult    ing    biotechnology    protein    esrs    species    generation    foci    quality    companies    powerful    life    partnership    critical    format    expertise    drugs    microbial    permeate    pastoris    industries    clear    bacillus    assurance    severe    coli    hosts    former    capitalises    super    latter    biology    academic    industrial    entrepreneurial    excess    biotherapeutics    pose    sectors    yeast    expression   

Project "Secreters" data sheet

The following table provides information about the project.

Coordinator
ACADEMISCH ZIEKENHUIS GRONINGEN 

Organization address
address: HANZEPLEIN 1
city: GRONINGEN
postcode: 9713 GZ
website: www.umcg.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 4˙087˙420 €
 EC max contribution 4˙087˙420 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2018
 Funding Scheme MSCA-ITN-ETN
 Starting year 2019
 Duration (year-month-day) from 2019-01-01   to  2022-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ACADEMISCH ZIEKENHUIS GRONINGEN NL (GRONINGEN) coordinator 531˙239.00
2    UNIVERSITY OF KENT UK (CANTERBURY, KENT) participant 606˙345.00
3    OULUN YLIOPISTO FI (OULU) participant 561˙611.00
4    ACIB GMBH AT (GRAZ) participant 528˙414.00
5    CELLTECH R&D LIMITED UK (SLOUGH) participant 303˙172.00
6    LONZA AG CH (BASEL) participant 281˙276.00
7    BOEHRINGER INGELHEIM RCV GMBH & CO KG AT (WIEN) participant 264˙207.00
8    AB Enzymes GmbH DE (Darmstadt) participant 252˙788.00
9    HUMBOLDT-UNIVERSITAET ZU BERLIN DE (BERLIN) participant 252˙788.00
10    UNIVERSITAET GREIFSWALD DE (GREIFSWALD) participant 252˙788.00
11    UNIVERSITATSMEDIZIN GREIFSWALD KORPERSCHAFT DES OFFENTLICHEN RECHTS DE (GREIFSWALD) participant 252˙788.00
12    UCB PHARMA SA BE (BRUXELLES) participant 0.00
13    BIOMIN HOLDING GMBH AT (GETZERSDORF BEI TRAISMAUER) partner 0.00
14    Gedeon Richter Plc. HU (Budapest) partner 0.00
15    POLYMUN SCIENTIFIC IMMUNBIOLOGISCHE FORSCHUNG GMBH AT (KLOSTERNEUBURG) partner 0.00
16    UNIVERSITAET FUER BODENKULTUR WIEN AT (WIEN) partner 0.00

Map

 Project objective

The ‘SECRETERS’ partnership aims to bring about a step change in the production of recombinant proteins, particularly Biotherapeutics and Industrial Enzymes. Both are critical products for the EU biotechnology sector, with combined markets in excess of $140 billion p.a.; the former are essential for the treatment of major diseases whereas the latter permeate every aspect of our daily life. Many proteins in these categories pose severe problems in production, especially disulphide-bonded proteins and new format 'difficult-to-express' proteins. SECRETERS will train a team of 15 ESRs to develop a new generation of super-producing microbial production hosts, including Escherichia coli, Bacillus species and the yeast Pichia pastoris. The project capitalises on a series of recent innovations and involves close collaboration between 5 academic Beneficiaries, who provide world-leading expertise in redox chemistry, synthetic biology and protein expression, and 5 non-academic Beneficiaries, who include some of the world's premier biotherapeutic and industrial enzyme companies. It will enable the biotherapeutics industry to produce challenging medicines at lower costs, resulting in new drugs and wider patient access, and allow the enzymes industry to deliver a range of powerful new products. SECRETERS will equip ESRs with the interdisciplinary and intersectoral skills required to thrive in these industries, with quality assurance systems embedded throughout the programme and a commitment to a wide-ranging dissemination/outreach programme. Based on a responsible innovation approach, with clear foci on research and entrepreneurial training, SECRETERS will deliver a team of superbly-trained scientists, poised to engage in some of Europe's most important biotechnology sectors.

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The information about "SECRETERS" are provided by the European Opendata Portal: CORDIS opendata.

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